Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Valérie, Haurie"'
1
Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation
Autor: Daniel Da Silva, Hélène Dumay-Odelot, Martina Prochazkova, Robert G. Roeder, Martin Teichmann, Stéphanie Durrieu-Gaillard, Valérie Haurie, Christophe Rey, Daniel Besser
Publikováno v: Proceedings of the National Academy of Sciences. 107:4176-4181
Transcription in eukaryotic nuclei is carried out by DNA-dependent RNA polymerases I, II, and III. Human RNA polymerase III (Pol III) transcribes small untranslated RNAs that include tRNAs, 5S RNA, U6 RNA, and some microRNAs. Increased Pol III transc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848fc814d916afe18679f8a3e16c8f9a
https://doi.org/10.1073/pnas.0914980107
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2
Pontin and Reptin, Two Related ATPases with Multiple Roles in Cancer
Autor: Otmar Huber, Alexandra Nicou, Valérie Haurie, Danièle Taras, Ludovic Ménard, Jean Rosenbaum
Publikováno v: Cancer Research
Cancer Research, American Association for Cancer Research, 2008, 68 (17), pp.6873-6. ⟨10.1158/0008-5472.CAN-08-0547⟩
Studies in model organisms or cultured human cells suggest potential implications in carcinogenesis for the AAA+ ATPases Pontin and Reptin. Both proteins are associated with several chromatin-remodeling complexes and have many functions including tra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae809c27ee02b4cbc4c2be465a75ae9
https://doi.org/10.1158/0008-5472.can-08-0547
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3
Protease-activated receptor 1 knockout reduces experimentally induced liver fibrosis
Autor: Anne Rullier, Nathalie Dugot-Senant, Jean Rosenbaum, Jennifer Gillibert-Duplantier, Gérard Déléris, Cyril Petibois, Pierre Costet, Gaelle Cubel, Valérie Haurie, Paulette Bioulac-Sage, Danièle Taras
Publikováno v: AJP-Gastrointestinal and Liver Physiology
AJP-Gastrointestinal and Liver Physiology, 2008, 294 (1), pp.G226-35. ⟨10.1152/ajpgi.00444.2007⟩
Thrombin inhibition protects against liver fibrosis. However, it is not known whether the thrombin profibrogenic effect is due to effects on blood coagulation or to signaling via protease-activated receptors (PARs). We took advantage of the lack of b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d43669519b81c8d6853c718c7987ecf
https://doi.org/10.1152/ajpgi.00444.2007
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4
Un peu moins de répit pour les cancers du foie ?
Autor: Jean Rosenbaum, Danièle Taras, Valérie Haurie, Ludovic Ménard
Publikováno v: médecine/sciences. 23:1029-1031
> Malgre d’importants progres recents, les mecanismes moleculaires de la carcinogenese hepatique restent tres imparfaitement connus. Plus encore, les perspectives therapeutiques sont extremement minces. C’est pour cette raison que notre equipe a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::485de1768e3540779ae8b8530fc1b425
https://doi.org/10.1051/medsci/200723111029
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5
Adenosine triphosphatase pontin is overexpressed in hepatocellular carcinoma and coregulated with reptin through a new posttranslational mechanism
Autor: Jean Rosenbaum, Philippe Metzler, Hervé Prats, Christian Touriol, Jessica Zucman-Rossi, Paulette Bioulac-Sage, Alexandra Nicou, Patrick Lestienne, Jérémy Fernandez, Danièle Taras, Ludovic Ménard, Valérie Haurie, Charles Balabaud
Publikováno v: Hepatology
Hepatology, Wiley-Blackwell, 2009, 50 (6), pp.1871-83. 〈10.1002/hep.23215〉
Hepatology, Wiley-Blackwell, 2009, 50 (6), pp.1871-83. ⟨10.1002/hep.23215⟩
Hepatology, 2009, 50 (6), pp.1871-83. ⟨10.1002/hep.23215⟩
International audience; Reptin and Pontin are related ATPases associated with stoichiometric amounts in several complexes involved in chromatin remodeling, transcriptional regulation, and telomerase activity. We found that Reptin was up-regulated in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae1c59ad0ab57d4e4a5adbee0667268
http://www.hal.inserm.fr/inserm-00408518/document
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6
In vivo silencing of Reptin blocks the progression of human hepatocellular carcinoma in xenografts and is associated with replicative senescence
Autor: Danièle Taras, Nathalie Dugot-Senant, Jean Rosenbaum, Benoit Rousseau, Ludovic Ménard, Pierre Costet, Aude Grigoletto, Valérie Haurie, Alexandra Nicou
Publikováno v: Journal of hepatology. 52(5)
Background & Aims We previously showed that Reptin is overexpressed in hepatocellular carcinoma (HCC), and that in vitro depletion of Reptin with siRNAs led to HCC cell growth arrest and apoptosis. Here, we asked whether in vivo targeting of Reptin i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c617bdd668ccf49ea98dfc353ef6368
https://pubmed.ncbi.nlm.nih.gov/20334944
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8
Dissecting regulatory networks by means of two-dimensional gel electrophoresis: application to the study of the diauxic shift in the yeast Saccharomyces cerevisiae
Autor: Valérie Haurie, Francis Sagliocco, Hélian Boucherie
Publikováno v: Proteomics. 4(2)
Using a proteomic approach based on the two-dimensional (2-D) gel analysis of synthesized proteins, we investigated the involvement of the Snf1 kinase pathway in the regulation of gene expression during the diauxic shift in Saccharomyces cerevisiae.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446cfc30f5a71a5a152e9887d0621f45
https://pubmed.ncbi.nlm.nih.gov/14760706
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9
The Snf1 protein kinase controls the induction of genes of the iron uptake pathway at the diauxic shift in Saccharomyces cerevisiae
Autor: Valérie Haurie, Francis Sagliocco, Hélian Boucherie
Publikováno v: The Journal of biological chemistry. 278(46)
In Saccharomyces cerevisiae the transition between the fermentative and the oxidative metabolism, called the diauxic shift, is associated with major changes in gene expression. In this study, we characterized a novel family of five genes whose expres
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c39180bbcbbe3b9d09c50240a7b1fe
https://pubmed.ncbi.nlm.nih.gov/12960168
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10
The transcriptional activator Cat8p provides a major contribution to the reprogramming of carbon metabolism during the diauxic shift in Saccharomyces cerevisiae
Autor: Francis Sagliocco, Paul Jenö, Hélian Boucherie, Valérie Haurie, Michel Perrot, Thierry Mini
Publikováno v: The Journal of biological chemistry. 276(1)
In yeast, the transition between the fermentative and the oxidative metabolism, called the diauxic shift, is associated with major changes in gene expression and protein synthesis. The zinc cluster protein Cat8p is required for the derepression of ni
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1976310b7366174ad4354eb69d4ad70
https://pubmed.ncbi.nlm.nih.gov/11024040
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