Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Valér Csernus"'
Autor:
Tamás Gaszner, József Farkas, Dániel Kun, Balázs Ujvári, Gergely Berta, Valér Csernus, Nóra Füredi, László Ákos Kovács, Hitoshi Hashimoto, Dóra Reglődi, Viktória Kormos, Balázs Gaszner
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
According to the three hit concept of depression, interaction of genetic predisposition altered epigenetic programming and environmental stress factors contribute to the disease. Earlier we demonstrated the construct and face validity of our three hi
Externí odkaz:
https://doaj.org/article/8a5afe64eaf8426e8f0dd45940d15cf6
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Corticotropin-releasing factor (CRF) immunoreactive (ir) neurons of the paraventricular nucleus of the hypothalamus (PVN) play pivotal role in the coordination of stress response. CRF-producing cells in the central nucleus of amygdala (CeA) and oval
Externí odkaz:
https://doaj.org/article/c56cdbcf5ec3410fa6b43efe2896536c
Autor:
László Ákos Kovács, Josef Andreas Schiessl, Anna Elisabeth Nafz, Valér Csernus, Balázs Gaszner
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
The hypothalamus-pituitary-adrenal axis (HPA) is the main regulator of the stress response. The key of the HPA is the parvocellular paraventricular nucleus of the hypothalamus (pPVN) controlled by higher-order limbic stress centers. The reactivity of
Externí odkaz:
https://doaj.org/article/06d7de9643604062941b4629f0c4a54f
Autor:
Viktória Kormos, Angéla Kecskés, József Farkas, Tamás Gaszner, Valér Csernus, Ammar Alomari, Dániel Hegedüs, Éva Renner, Miklós Palkovits, Dóra Zelena, Zsuzsanna Helyes, Erika Pintér, Balázs Gaszner
Publikováno v:
Journal of Psychiatry and Neuroscience. 47:E162-E175
Transient receptor potential ankyrin 1 (TRPA1), a cation channel, is expressed predominantly in primary sensory neurons, but its central distribution and role in mood control are not well understood. We investigated whether TRPA1 is expressed in the
Autor:
Viktória Kormos, Anna Elisabeth Nafz, László Gáspár, Hitoshi Hashimoto, Jozsef Farkas, Balázs Gaszner, László Á. Kovács, Valér Csernus, Balázs Ujvári, Dóra Reglődi, Tamás Gaszner
Publikováno v:
Neuroscience. 354:11-29
Major depression is a common cause of chronic disability. Despite decades of efforts, no equivocally accepted animal model is available for studying depression. We tested the validity of a new model based on the three-hit concept of vulnerability and
Autor:
Kata Csekő, Éva Borbély, Bálint Scheich, Valér Csernus, István M. Ábrahám, Balázs Gaszner, Zsuzsanna Helyes
Publikováno v:
Neuroscience. 346:320-336
The somatostatin 4 receptor (sst4) is widely expressed in stress-related brain areas (e.g. hippocampus, amygdala) and regulates the emotional behavior in acute situations. Since its importance in chronic stress-induced complex pathophysiological alte
Publikováno v:
General and Comparative Endocrinology. 188:226-231
The circadian clock in the chicken pineal model develops before hatching, at around the 17th embryonic day (ED17). By this stage, it runs in synchrony with environmental cues. To address if phase resetting mechanisms are comparable to those of post-h
Autor:
László Á. Kovács, Valér Csernus, Hitoshi Hashimoto, Dóra Reglődi, Jozsef Farkas, Zsuzsanna Helyes, László Gáspár, Tamás Gaszner, András Balogh, Viktória Kormos, Balázs Gaszner
Publikováno v:
Neuroscience. 330
Pituitary adenylate cyclase-activating polypeptide (PACAP) has been implicated in stress adaptation with potential relevance in mood disorder management. PACAP deficient (KO) mice on CD1 background were shown to have depression-like phenotype. Here w
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 84:27-36
The effect of the neurotoxic drug, 6-hydroxy-dopamine (6-OHDA) on the testicular growth, the compensatory testicular hypertrophy, the testicular cytology and the serum testosterone level was studied in immature rats. Unilateral injection of 33 microg
Autor:
Valér Csernus, János Sándor, Á Müller, Franz Halberg, Rita Jozsa, G. Cornélissen, András Oláh, Michal Zeman, Willemijntje A. Hoogerwerf
Publikováno v:
Neurotoxicity Research. 13:85-96
While certain circadian hormonal changes are prominent, their predictable assessment requires a standardization of conditions of sampling. The 24-hour rhythm in circulating corticosterone of rodents, known since the 1950s, was studied as a presumed p