Impaired beta-oxidation increases vulnerability to influenza A infection

Autor: Klaus Schughart, Diana Cabrera, Heike Kollmus, Carolin Pilzner, Sebastiaan M. Van Liempd, Juan M. Falcón-Pérez

Publikováno v: The Journal of biological chemistry
United States
The Journal of Biological Chemistry

Influenza A virus (IAV) infection casts a significant burden on society. It has particularly high morbidity and mortality rates in patients suffering from metabolic disorders. The aim of this study was to relate metabolic changes with IAV susceptibil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35df79d0e1826add7a81f0ba6216551f
https://hdl.handle.net/10033/623093

Gene interactions observed with the HDL-c blood lipid, intakes of protein, sugar and biotin in relation to circulating homocysteine concentrations in a group of black South Africans

Autor: Jacomina P. du Plessis, Lizelle Zandberg, Cornelie Nienaber-Rousseau, Alida Melse-Boonstra

Publikováno v: Molecular Genetics and Metabolism Reports, 22
Molecular Genetics and Metabolism Reports 22 (2020)
Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports, Vol 22, Iss, Pp-(2020)

Background: Elevated homocysteine (Hcy) is associated with several pathologies. Gene–diet interactions related to Hcy might be used to customize dietary advice to reduce disease incidence. To explore this possibility, we investigated interactions b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e094a32b1cc86c261c27a4bc390a2c80
https://doi.org/10.1016/j.ymgmr.2019.100556

A codon-optimized green fluorescent protein for live cell imaging in Zymoseptoria tritici

Autor: Nicholas J. Talbot, Sreedhar Kilaru, Martin Schuster, Darren M. Soanes, Congping Lin, David J. Studholme, Gero Steinberg

Publikováno v: Fungal Genetics and Biology

Highlights • We generated a Z. tritici codon-optimized gene for green fluorescent protein (ZtGFP). • In epi-fluorescence and confocal microscopy, ZtGFP is brighter and more stable than eGFP. • We provide 3 vectors that carry AcGFP, eGFP and ZtG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928c19e214a14d5cc5577371085d6841

Genetic and environmental interaction in allergy and asthma

Autor: Stephen T. Holgate

Publikováno v: The Journal of Allergy and Clinical Immunology

Asthma is an inflammatory disorder of the airways involving coordinate up-regulation of TH2-type cytokines encoded in a cluster on chromosome 5q31-33 on T cells and inflammatory cells. There is also a requirement for local airway susceptibility facto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ae1d58bfa7a7bb55a2087e2b4dde96
https://pubmed.ncbi.nlm.nih.gov/10588993

Short-chain fatty acids reprogram metabolic profiles with the induction of reactive oxygen species production in human colorectal adenocarcinoma cells.

Autor: Huang C; State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China., Deng W; Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, Hubei, China., Xu HZ; Department of Pediatrics, Division of Infectious Diseases, College of Medicine, University of Florida, Gainesville, FL, USA., Zhou C; Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, Hubei, China., Zhang F; Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China., Chen J; State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China., Bao Q; State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China.; University of Chinese Academy of Sciences, Beijing, China., Zhou X; State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China.; University of Chinese Academy of Sciences, Beijing, China.; Optics Valley Laboratory, Hubei 430074, China., Liu M; State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China.; University of Chinese Academy of Sciences, Beijing, China.; Optics Valley Laboratory, Hubei 430074, China., Li J; Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, Hubei, China.; University of Chinese Academy of Sciences, Beijing, China., Liu C; State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China.; University of Chinese Academy of Sciences, Beijing, China.; Optics Valley Laboratory, Hubei 430074, China.

Publikováno v: Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2023 Feb 13; Vol. 21, pp. 1606-1620. Date of Electronic Publication: 2023 Feb 13 (Print Publication: 2023).