Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Vakal A. P."'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Tracer antibodies, which are labelled with fluorescent or other type of reporter molecules, are widely employed in diagnostic immunoassays. Time-resolved fluorescence immunoassay (TRFIA), recognized as one of the most sensitive immunoassay t
Externí odkaz:
https://doaj.org/article/a83d4d541b8c4f58b36c53d1d34a0e41
Autor:
Hans Merlin Tsahnang Fofack, Maraf Mbah Bake, Simon Petry, Baruch A. Ateba, Pascal Amoa Onguéné, Haydar Mohammad-Salim, Fidele Ntie-Kang, Luc Meva'a Mbaze, Serhii Vakal, Cyril A Kenfack
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35191- (2024)
In this study, we screened novel dipeptidyl peptidase IV (DPP4) inhibitors from the ConMedNP library consisting of 3507 molecules. Interestingly, molecular docking, ADMET, and the anti-diabetic activity predictions suggest that three molecules, namel
Externí odkaz:
https://doaj.org/article/60434f540bfd4bf3a8958ceb87148e76
Akademický článek
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Akademický článek
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Autor:
Lin Chen, Jie Deng, Ailing Yu, Yuhan Hu, Bo Jin, Pengyuan Du, Jianhong Zhou, Lei Lei, Yuan Wang, Serhii Vakal, Xingyi Li
Publikováno v:
Bioactive Materials, Vol 10, Iss , Pp 420-429 (2022)
Boosting transcorneal permeability and pharmacological activity of drug poses a great challenge in the field of ocular drug delivery. In the present study, we propose a drug-peptide supramolecular hydrogel based on anti-inflammatory drug, dexamethaso
Externí odkaz:
https://doaj.org/article/0ae567cf3ca14845872684223abbbabd
Autor:
Wu Zheng, Yijia Feng, Zhenhai Zeng, Mengqian Ye, Mengru Wang, Xin Liu, Ping Tang, Huiping Shang, Xiaoting Sun, Xiangxiang Lin, Muran Wang, Zhengzheng Li, Yiyun Weng, Wei Guo, Sergii Vakal, Jiang-fan Chen
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background Multiple sclerosis (MS) is one of the most common autoimmune disorders characterized by the infiltration of immune cells into the brain and demyelination. The unwanted immunosuppressive side effect of therapeutically successful na
Externí odkaz:
https://doaj.org/article/24f70e097e9e4a248de68f2a47e85da5
Publikováno v:
Social Development & Security, Vol 11, Iss 1, Pp 13-21 (2021)
У статті проведено аналіз відомих конструктивних рішень, що використовуються для комплектування некерованих авіаційних ракет та некер
Externí odkaz:
https://doaj.org/article/1f6401e18f5742e78fd2992498ff8c4c
Autor:
Maycon Vinicius Damasceno de Oliveira, Renan Machado Furtado, Kauê S. da Costa, Serhii Vakal, Anderson H. Lima
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Peptidoglycan is a cross-linked polymer responsible for maintaining the bacterial cell wall integrity and morphology in Gram-negative and Gram-positive bacteria. The peptidoglycan pathway consists of the enzymatic reactions held in three steps: cytop
Externí odkaz:
https://doaj.org/article/0b4e90a1c5424abc964e5dea7203ffe8
Publikováno v:
ACS Omega, Vol 5, Iss 38, Pp 24927-24934 (2020)
Externí odkaz:
https://doaj.org/article/41f759d8fc4545d6bafbbcc0be4dcb35
Autor:
Elisabeth Gludovacz, Kornelia Schuetzenberger, Marlene Resch, Katharina Tillmann, Karin Petroczi, Markus Schosserer, Sigrid Vondra, Serhii Vakal, Gerald Klanert, Jürgen Pollheimer, Tiina A Salminen, Bernd Jilma, Nicole Borth, Thomas Boehm
Publikováno v:
eLife, Vol 10 (2021)
Background: Excessive plasma histamine concentrations cause symptoms in mast cell activation syndrome, mastocytosis, or anaphylaxis. Anti-histamines are often insufficiently efficacious. Human diamine oxidase (hDAO) can rapidly degrade histamine and
Externí odkaz:
https://doaj.org/article/d7281aa1f5af4be284b2a714515c12fb