Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vaiva Petrenaite"'
Publikováno v:
Epilepsy research. 182
To evaluate the impact of genetic polymorphisms of UGT enzymes (UGT1A4, UGT2B7, UGT2B15 and UGT 2B17) and the transporter protein ABCB1 on Lamotrigine (LTG) metabolism.Single nucleotide polymorphisms UGT1A4*2 (P24T, c.70CA), UGT1A4*3 (L48V c.142TG),
Autor:
Birgitte Forsom Sondal, Zarouhi Hertz, Brenda Diputado, Meritxell Martinez Ferri, Odo Hildenhagen, Aldo Paggi, Gerhard Luef, Jakob Christensen, John Craig, Jana Zárubová, Gordana Kiteva-Trencevska, Raffaele Rocchi, Erik Tauboll, Lisa Gordon, Terttu Heikinheimo-Connell, Uden Navn, Ketevan Khomeriki, Iva Marečková, Erminio Bonizzoni, Michela Cecconi, Lone Rodam, Astrid Carius, Ineke Hogenesch, Katarzyna Miesczanleh, Angelo Labate, Eva Kumlien, Claus Albretsen, Torbjörn Tomson, Chiara Pantaleoni, David Sopelana Garay, Albertina Franza, Imad Halawa, Stefan Juhl, Emilio Perucca, Pia Gellert, Daniela Marino, Aline Russell, E. Kluck, Eylert Brodtkorb, Luigi Maria Specchio, Isabel Pires, Pietro Pignatta, Frank J.E. Vajda, Anette Huuse Farmen, Hans Lindsten, Boštjan Čebular, Maria Paola Canevini, Jens Arentsen, Francesca Faravelli, Bettina Schmitz, Noémi Becser Andersen, Birgit Müffelmann, Petr Bušek, T.-Y. Chang, Alma Sikiric, Judith Osseforth, Elias Zakharia, Elsebeth Bruun Christensen, Gemma Sansa Fayos, Vaiva Petrenaite, Alessandra Pistelli, Eliana Pastor, Hana Krijtová, Tim Hendgen, Leonor Cabral-Lim, Marina Trivisano, Hsiang-Yu Yu, Renata Listonova, Torleiv Svendsen, Vladimír Safcák, Nicoletta Foschi, Kristina Malmgren, Reetta Kälviäinen, Dag Aurlien, Martin J. Brodie, Maria Dolores Castro Vilanova, Anders Nilsson, Jesús Antonio Riuz Gimenez, Christian Samsonsen, Katsuyuki Fukushima, Maria Strandberg, Masaaki Kato, Giovanni De Maria, Katrine Haggag, Anna Maija Saukkonen, Maja Milovanovic, Masahiro Mizobuchi, Peter Mattsson, Bernhard Oehl, Anne Sabers, Juan Luis Becerra Cuñat, Mogens Worm, Antonio Gambardella, Miri Neufeld, Reina Roivainen, Kiyohito Terada, Janne Marit Ertresvåg, Birthe Pedersen, Gisela Rytířová, Claudia Cagnetti, Sanjeev V Thomas, Dick Lindhout, Silvia Kochen, Katherine Turner, Dieter Dennig, Luisa Antonini, Dina Battino, Laura Broglio, Aileen McGonigal, Helena Gauffin, Andrea Ortenzi, Ismael Barzinji, Hideyuki Ohtani, Rasmus Lossius, Elisabeth Robert-Gnansia, Morteza Zarifi-Oskoie, Leif Gjerstad, Barbara Tettenborn, Stephanie Hödl, Martin Kurthen, Barbara Mostacci, Alejandro De Marinis, Natalia Bohorquez Morera, Karl O. Nakken, Yushi Inoue, Germaine Kenou Van Rijckevorssel, Theresa Lasch, Iñigo Garamendi Ruiz, Silje Alvestad, Eugène van Puijenbroek, Anders Lundgren, Elena Zambrelli, Toni Escartin, Bernhard J. Steinhoff, Dominique Flügel
Publikováno v:
Lancet Neurology, 17(6), 530-538. ELSEVIER SCIENCE INC
Christensen, J, Brændgaard, H & EURAP Study Group 2018, ' Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry ', Lancet Neurology, vol. 17, no. 6, pp. 530-538 . https://doi.org/10.1016/S1474-4422(18)30107-8
Epilepsy Currents
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Christensen, J, Brændgaard, H & EURAP Study Group 2018, ' Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry ', Lancet Neurology, vol. 17, no. 6, pp. 530-538 . https://doi.org/10.1016/S1474-4422(18)30107-8
Epilepsy Currents
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Background: Evidence for the comparative teratogenic risk of antiepileptic drugs is insufficient, particularly in relation to the dosage used. Therefore, we aimed to compare the occurrence of major congenital malformations following prenatal exposure
Autor:
Inger Öhman, Anne Sabers, Torbjörn Tomson, Vaiva Petrenaite, Lena Ekström, Ditte Sæbye, Thomas Hansen
Publikováno v:
Epilepsy Research. 140:199-208
Objective To evaluate the impact of maternal UGT1A4 and UGT2B7 genetic polymorphisms and sex of foetus on gestation-induced changes in lamotrigine (LTG) clearance during pregnancy and post-partum (PP). Methods Single nucleotide polymorphisms UGT1A4 1
Publikováno v:
Seizure. 53
Eslicarbazepine acetate (ESL) is indicated for treatment of focal epilepsy. Our aim was to evaluate the effect and tolerability of ESL in elderly and younger adults. The primary objective was to measure changes in seizure frequency before and after a
Autor:
Vaiva Petrenaite, Anne Sabers
Publikováno v:
Epilepsia. 50:2163-2166
Summary Previous studies have demonstrated that the pharmacokinetics of the new antiepileptic drug (AED) lamotrigine (LTG) are substantially influenced by pregnancy and are more likely to be associated with seizure deterioration in pregnancy compared
Autor:
Anne Sabers, Vaiva Petrenaite
Publikováno v:
Expert Review of Clinical Pharmacology. 1:129-136
A substantial proportion of women with epilepsy experience seizure deterioration during pregnancy. This is most likely explained by a drop in plasma levels of antiepileptic drugs (AEDs) as a consequence of altered drug pharmacokinetics. It has been k
Autor:
Jørn Atterman, Per Sidenius, Torbjörn Tomson, Vaiva Petrenaite, Inger Öhman, Anne Sabers, Jakob Christensen
Publikováno v:
Christensen, J, Petrenaite, V, Attermann, J, Sidenius, P, Öhman, I, Tomson, T & Sabers, A 2007, ' Oral contraceptives induce lamotrigine metabolism: evidence from a double-blind, placebo-controlled trial ', Epilepsia, vol. 48, no. 3, pp. 484-9 . https://doi.org/10.1111/j.1528-1167.2007.00997.x
PURPOSE: This study evaluates the effect of oral contraceptives on lamotrigine (LTG) plasma concentrations and urine excretion of LTG metabolites in a double-blind, placebo-controlled, crossover study in patients with epilepsy. METHODS: Women with ep
Publikováno v:
Epilepsy research. 84(2-3)
Thirteen pregnancies in ten women on oxcarbazepine (OXC) monotherapy and one pregnancy in a woman on OXC and topiramate therapy were retrospectively analyzed. A significant decrease of ratio plasma concentration of 10-monohydroxy derivate (MHD) of ox