Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Vaishnavi Ganti"'
Autor:
Mayur Narkhede, Nancy L. Bartlett, Sami Ibrahimi, Leslie Popplewell, Anna Seto, Jamie Bates, Yeonju Lee, Vaishnavi Ganti, Ling Han, Tianling Chen, Manish R. Patel
Publikováno v:
eJHaem, Vol 4, Iss 2, Pp 370-380 (2023)
Abstract Signal regulatory protein alpha (SIRPα) is the receptor for cluster of differentiation (CD)47, a potent “don't eat me” signal for macrophages. Disruption of CD47‐SIRPα signaling in the presence of prophagocytic signals can lead to en
Externí odkaz:
https://doaj.org/article/8470c6427c364eb6b41fe36383a68d9f
Autor:
Holger Wesche, Che-Leung Law, Patrick A. Baeuerle, Timothy Z. Yu, Laurie Tatalick, Kenneth Sexton, Purbasa Patnaik, Kathryn L. Strobel, Susan D. Jones, Adrie Jones, Vaishnavi Ganti, Wade H. Aaron, Bryan D. Lemon, Richard J. Austin, Mary Ellen Molloy
Purpose:Mesothelin (MSLN) is a glycophosphatidylinositol-linked tumor antigen overexpressed in a variety of malignancies, including ovarian, pancreatic, lung, and triple-negative breast cancer. Early signs of clinical efficacy with MSLN-targeting age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb32ac1e74423fb577ba10f3003d4017
https://doi.org/10.1158/1078-0432.c.6530192.v1
https://doi.org/10.1158/1078-0432.c.6530192.v1
Autor:
Holger Wesche, Che-Leung Law, Patrick A. Baeuerle, Timothy Z. Yu, Laurie Tatalick, Kenneth Sexton, Purbasa Patnaik, Kathryn L. Strobel, Susan D. Jones, Adrie Jones, Vaishnavi Ganti, Wade H. Aaron, Bryan D. Lemon, Richard J. Austin, Mary Ellen Molloy
Supplementary data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a58f328683170de211f22dc75c58662
https://doi.org/10.1158/1078-0432.22479320
https://doi.org/10.1158/1078-0432.22479320
Autor:
Vaishnavi Ganti
Publikováno v:
International Journal of Emerging Trends in Engineering Research. 8:1815-1818
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e1921dc8851f01e613c83a12c8695a6
https://doi.org/10.30534/ijeter/2020/54852020
https://doi.org/10.30534/ijeter/2020/54852020
Autor:
Che-Leung Law, Holger Wesche, Timothy Yu, Richard J. Austin, Vaishnavi Ganti, Mary Ellen Molloy, Kathryn L. Strobel, Susan D. Jones, Purbasa Patnaik, Laurie Tatalick, A. Jones, Kenneth Sexton, Patrick A. Baeuerle, Wade Aaron, Lemon Bryan D
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 27(5)
Purpose: Mesothelin (MSLN) is a glycophosphatidylinositol-linked tumor antigen overexpressed in a variety of malignancies, including ovarian, pancreatic, lung, and triple-negative breast cancer. Early signs of clinical efficacy with MSLN-targeting ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a05654dbacd41d8f81d7ec5c1ac869
https://pubmed.ncbi.nlm.nih.gov/33262134
https://pubmed.ncbi.nlm.nih.gov/33262134
Autor:
Holger Wesche, Tomasz M. Beer, Johanna C. Bendell, Vaishnavi Ganti, Lawrence Fong, Xin Gao, Che-Leung Law, Ashley E. Ross, Mark N. Stein, Aaron Weitzman, Johann S. de Bono, Lemon Bryan D, Richard C. Austin
Publikováno v:
Journal of Clinical Oncology. 38:5552-5552
5552 Background: HPN424 is a first-in-class, prostate-specific membrane antigen (PSMA)-targeting T-cell engager designed as a small, globular protein to enable efficient solid-tumor penetration with prolonged half-life. HPN424 is derived from the Tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56a6f66ce650d59e0305ac00632350d9
https://doi.org/10.1200/jco.2020.38.15_suppl.5552
https://doi.org/10.1200/jco.2020.38.15_suppl.5552
Autor:
SuChun Hseih, Daping Zhang, Daniel S. Spellman, Shuli Zhang, Yaoli Song, Harish Shankaran, Veronica Juan, Michael Judo, Sophia E Elie, Enrique Escandón, Vaishnavi Ganti, Divas Neupane, Wolfgang Seghezzi, Laurence Fayadat-Dilman, Mohammad Tabrizi
Publikováno v:
The AAPS journal. 21(3)
Assessment of the factors that regulate antibody exposure-response relationships in the relevant animal models is critical for the design of successful translational strategies from discovery to the clinic. Depending on the specific clinical indicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c85ebf94bfd8e0e0eba37382af7c29b
https://pubmed.ncbi.nlm.nih.gov/30868312
https://pubmed.ncbi.nlm.nih.gov/30868312
Autor:
Golzar Hemmati, Holger Wesche, Richard J. Austin, Thomas Evans, Mary Ellen Molloy, Kathryn Kwant, Llewelyn Lao, Vaishnavi Ganti, Stephen Yu, Jessica O’Rear, Che-Leung Law, Lemon Bryan D, Michael Cremin, Wade Aaron, Evan Callihan, Laura Sun, Manasi Barath, Timothy Yu, Maria Gamez
Publikováno v:
Molecular Cancer Therapeutics. 18:C033-C033
HPN328: An Anti-DLL3 T Cell Engager for Treatment of Small Cell Lung Cancer Delta-like protein 3 (DLL3) is a Notch inhibitory ligand is expressed in more than 70% of small cell lung cancers (SCLCs), while there is little to no surface expression in n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b878b5c536444ed9bad242896fa81bb
https://doi.org/10.1158/1535-7163.targ-19-c033
https://doi.org/10.1158/1535-7163.targ-19-c033
Publikováno v:
The AAPS journal. 20(4)
With the recent advances in cancer immunotherapy, it is now evident that the antigen-specific activation of the patients' immune responses can be utilized for achieving significant therapeutic benefits. Novel molecules have been developed and promisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed59bda6917524ad6eb86b3435d2133
https://pubmed.ncbi.nlm.nih.gov/29704129
https://pubmed.ncbi.nlm.nih.gov/29704129
Autor:
Mohammad Tabrizi, Vaishnavi Ganti
Publikováno v:
Development of Antibody-Based Therapeutics ISBN: 9789811304958
Biologics are one of the fastest growing subsets of pharmaceuticals today. In 2016, ten monoclonal antibodies were approved by the FDA for diverse conditions such as psoriasis and cancer. This high number of approvals followed the previous record num
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35c0ab7859bce664b193e09dce091a44
https://doi.org/10.1007/978-981-13-0496-5_2
https://doi.org/10.1007/978-981-13-0496-5_2