Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Vaishali R, Moulton"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cytotoxic CD8 T cells are crucial for the host antigen-specific immune response to viral pathogens. Here we report the identification of an essential role for the serine/arginine-rich splicing factor (SRSF) 1 in CD8 T cell homeostasis and function. S
Externí odkaz:
https://doaj.org/article/4eb2b3e7290e4f54a2a753933679b638
Autor:
Hao Li, Iannis E. Adamopoulos, Vaishali R. Moulton, Isaac E. Stillman, Zach Herbert, James J. Moon, Amir Sharabi, Suzanne Krishfield, Maria G. Tsokos, George C. Tsokos
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Splenic marginal zone macrophages can establish immune tolerance and limit the development of systemic lupus erythematosus (SLE). Here the authors show that these cells do this by clearing apoptotic cells, and defects in these cells result in the gen
Externí odkaz:
https://doaj.org/article/e6b55468c2854d60ac861be67cb25f57
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/c493bb6fe74c4db5abf34c40c3e80228
Autor:
Varnica Bajaj, Nirupa Gadi, Allison P. Spihlman, Samantha C. Wu, Christopher H. Choi, Vaishali R. Moulton
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
The novel coronavirus severe acute respiratory syndrome coronavirus 2 causing the Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total cases and over 1.6 million deaths worldwide as of early December 2020. An overw
Externí odkaz:
https://doaj.org/article/6968d5727b99462989998ed9ba42ac06
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The SARS-CoV-2 novel coronavirus has caused the COVID-19 pandemic with over 35 million cases and over a million deaths worldwide as of early October 2020. The populations most affected are the elderly and especially those with underlying comorbiditie
Externí odkaz:
https://doaj.org/article/0bdfd8db4db64d498ba5f9eabe45349c
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The novel severe acute respiratory syndrome coronavirus 2, the cause of the coronavirus disease 2019 (COVID-19) pandemic, has ravaged the world, with over 22 million total cases and over 770,000 deaths worldwide as of August 18, 2020. While the elder
Externí odkaz:
https://doaj.org/article/d57d724e53b14059ba8dc2ef6c916dd4
Publikováno v:
Molecular Immunology. 152:140-152
Regulatory T cells (Tregs) are vital for maintaining immune self-tolerance, and their impaired function leads to autoimmune disease. Mutations in FoxP3, the master transcriptional regulator of Tregs, leads to immune dysregulation, polyendocrinopathy,
Autor:
Vaishali R. Moulton
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Women have stronger immune responses to infections and vaccination than men. Paradoxically, the stronger immune response comes at a steep price, which is the high incidence of autoimmune diseases in women. The reasons why women have stronger immunity
Externí odkaz:
https://doaj.org/article/7c8fdfa335c04d9f96268d81103e1faa
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Systemic lupus erythematosus (SLE) is a chronic multi-organ debilitating autoimmune disease, which mainly afflicts women in the reproductive years. A complex interaction of genetics, environmental factors and hormones result in the breakdown of immun
Externí odkaz:
https://doaj.org/article/0a0f0d004c454b078018c76c4e0123c4
Autor:
Suzanne Krishfield, Elena N Cravens, Suruchi A Ramanujan, Vaishali R. Moulton, Vasileios C. Kyttaris
Publikováno v:
Arthritis & Rheumatology (Hoboken, N.j.)
Objective Autoimmune diseases affect women disproportionately more than men. Estrogen is implicated in immune cell dysfunction, yet its precise molecular roles are not fully known. We recently identified new roles for serine/arginine‐rich splicing