Výsledky vyhledávání - "Vaishali M Gambhire"

Solid Lipid Nanoparticles of Dronedarone Hydrochloride for Oral Delivery: Optimization, In Vivo Pharmacokinetics and Uptake Studies

Autor: Vaishali M Gambhire, Nisharani S. Ranpise, Makarand S Gambhire

Publikováno v: Pharmaceutical Nanotechnology. 7:375-388

Background: Dronedarone HCl (DRD), owing to its poor aqueous solubility and extensive presystemic metabolism shows low oral bioavailability of about 4% without food, which increases to approximately 15% when administered with a high fat meal. Objecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b124fb2f118e4f368379f1a9101c1bc
https://doi.org/10.2174/2211738507666190802140607

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Development and Optimization of Mirabegron Solid Lipid Nanoparticles as an Oral Drug Delivery for Overactive Bladder

Autor: Dhruvi Panchal, Prajakta Raut, Makarand S Gambhire, Vaishali M Gambhire

Publikováno v: Pharmaceutical nanotechnology. 9(2)

Background: Mirabegron (MBN), a β-3 adrenergic agent, is used in the treatment of overactive bladder. MBN has alow water solubility, high first-pass metabolism, and low bioavailability, consequently having poor absorption in the gastrointestinal tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5892fc6b0effa0f7e47c8630caf172
https://pubmed.ncbi.nlm.nih.gov/33504321

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Atorvastatin-loaded lipid nanoparticles: antitumor activity studies on MCF-7 breast cancer cells

Autor: Shital M Salunkhe, Vaishali M Gambhire, Makarand S Gambhire

Publikováno v: Drug Development and Industrial Pharmacy. 44:1685-1692

Atorvastatin is a synthetic statin commonly used in the treatment of hypercholesterolemia. Apart from this, statins appear to have pleiotropic effects, including modulation of cell growth, apoptosis. Through modulation of these pathways, statins have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46524465c4fdae272e3ba8075b4b1f2
https://doi.org/10.1080/03639045.2018.1492605

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Statistical Optimization of Sertraline Hydrochloride Loaded Solid Lipid Nanoparticles Using Box-Behnken Design

Autor: Vaishali M. Gambhire, Kishor N. Gujar, Varsharani D. Patil

Publikováno v: International Journal of PharmTech Research. 11:206-217

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f2979edd8939e6e33a38504ea7b515cd
https://doi.org/10.20902/ijptr.2018.11302

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Statistical optimization of dithranol-loaded solid lipid nanoparticles using factorial design

Autor: Vaishali M Gambhire, Mangesh R. Bhalekar, Makarand Suresh Gambhire

Publikováno v: Brazilian Journal of Pharmaceutical Sciences; Vol. 47 No. 3 (2011); 503-511
Brazilian Journal of Pharmaceutical Sciences; Vol. 47 Núm. 3 (2011); 503-511
Brazilian Journal of Pharmaceutical Sciences; v. 47 n. 3 (2011); 503-511
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Volume: 47, Issue: 3, Pages: 503-511, Published: SEP 2011
Brazilian Journal of Pharmaceutical Sciences, Vol 47, Iss 3, Pp 503-511 (2011)

This study describes a 3² full factorial experimental design to optimize the formulation of dithranol (DTH) loaded solid lipid nanoparticles (SLN) by the pre-emulsion ultrasonication method. The variables drug: lipid ratio and sonication time were s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c86c4299c2ad54addd1b24999cdec9
https://www.revistas.usp.br/bjps/article/view/10911

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