Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Vaishali I. Parekh"'
Publikováno v:
International Journal of Endocrinology, Vol 2015 (2015)
Lipoma in patients with the multiple endocrine neoplasia type 1 (MEN1) syndrome is a type of benign fat-cell tumor that has biallelic inactivation of MEN1 that encodes menin and could serve as a model to investigate normal and pathologic fat-cell (ad
Externí odkaz:
https://doaj.org/article/6ee635b583854b619852e60cb2ce4b09
Autor:
James Welch, Adel Mandl, Robert T. Jensen, Vaishali I. Parekh, Mary Walter, Lee S. Weinstein, Jaydira Del Rivero, R. Taylor Ripley, Smita Jha, Gayathri Kapoor, Sunita K. Agarwal, Jenny E Blau, William F. Simonds, David S. Schrump
Publikováno v:
Endocrine-Related Cancer
Patients with the multiple endocrine neoplasia type 1 (MEN1) syndrome carry germline heterozygous loss-of-function mutations in the MEN1 gene which predisposes them to develop various endocrine and non-endocrine tumors. Over 90% of the tumors show lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b200d4038c2dd8a9526d9ef10b4275
http://europepmc.org/articles/PMC8558845
http://europepmc.org/articles/PMC8558845
Autor:
Akua Graf, James Welch, Rashika Bansal, Adel Mandl, Vaishali I Parekh, Craig Cochran, Elliot Levy, Naris Nilubol, Dhaval Patel, Samira Sadowski, Smita Jha, Sunita K Agarwal, Corina Millo, Jenny E Blau, William F Simonds, Lee S Weinstein, Jaydira Del Rivero
Publikováno v:
J Endocr Soc
Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) may occur in 30% to 90% of patients with multiple endocrine neoplasia type 1 (MEN1). However, only 1% of GEP-NETs are grade 3 (G3). Given the rarity of these aggressive tumors, treatment of adva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6874d0484ba960ccf4ad52a18bdc91a
https://europepmc.org/articles/PMC9469921/
https://europepmc.org/articles/PMC9469921/
Autor:
Raisa Ghosh, Maya Lee, Rana Tora, James Welch, Vaishali I Parekh, Jaydira del Rivero, William F Simonds, Lee Scott Weinstein, Jenny E Blau, Sunita K Agarwal, Smita Jha
Publikováno v:
Journal of the Endocrine Society. 6:A486-A487
Multiple studies have shown that approximately 50-70% of patients with MEN1 die of causes directly related to MEN1 particularly gastroenteropancreatic (GEP) neuroendocrine tumors (NETs). While non-functional GEP-NETs are the most common in the genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65ecc8418cccace3723737087220944a
https://doi.org/10.1210/jendso/bvac150.1010
https://doi.org/10.1210/jendso/bvac150.1010
Autor:
Electron Kebebew, Sunita K. Agarwal, Sita D. Modali, William F. Simonds, Lee S. Weinstein, James Welch, Vaishali I. Parekh
Publikováno v:
Endocrine-Related Cancer. 25:L31-L35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af1ce83de92bc5eb007883ced929f326
https://doi.org/10.1530/erc-17-0311
https://doi.org/10.1530/erc-17-0311
Publikováno v:
Endocrinology
The insulin-secreting pancreatic neuroendocrine tumors, insulinomas, characterized by increased pancreatic islet β-cell proliferation, express the phosphorylated isoform of the β-cell differentiation factor HLXB9 that interacts with NONO/p54NRB, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::245c4e710bb4dc72393b57f349d7176b
http://europepmc.org/articles/PMC5793795
http://europepmc.org/articles/PMC5793795
Autor:
Lee S. Weinstein, Jaydira Del Rivero, Jenny E Blau, Sunita K. Agarwal, Craig Cochran, David S. Schrump, James Welch, Akua Graf, Adel Mandl, William F. Simonds, Smita Jha, Vaishali I. Parekh
Publikováno v:
Journal of the Endocrine Society
Background: Multiple endocrine neoplasia type 1 (MEN1) is an inherited tumor syndrome with autosomal dominant inheritance. Thymic neuroendocrine tumors (NETs) are known manifestations of MEN1 occurring in 2-8% of patients. However, thymomas, a type o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021b330e9282146f88059ec7b39538cd
https://doi.org/10.1210/jendso/bvab048.2061
https://doi.org/10.1210/jendso/bvab048.2061
Autor:
James Welch, Robert T. Jensen, Vaishali I. Parekh, Jenny E Blau, Sunita K. Agarwal, William F. Simonds, Adel Mandl, Roxanne Merkel, Lee S. Weinstein, Zahraa Abdul Sater, Jaydira Del Rivero, David S. Schrump, Craig Cochran, Gayathri Veeraraghavan
Publikováno v:
Journal of the Endocrine Society
Patients with the multiple endocrine neoplasia 1 (MEN1) syndrome develop various tumors during their lifetime. One of the rare manifestations observed in MEN1 patients is thymic neuroendocrine tumor (Th-NET) or thymic carcinoid, which is a major caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a836bbeaa87317946cfb4a0bdeb8103d
http://europepmc.org/articles/PMC6553303
http://europepmc.org/articles/PMC6553303
Autor:
Vaishali I, Parekh, Sita D, Modali, James, Welch, William F, Simonds, Lee S, Weinstein, Electron, Kebebew, Sunita K, Agarwal
Publikováno v:
Endocrine-related cancer. 25(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84c9471d9682829d00ca50739a6afd3e
https://pubmed.ncbi.nlm.nih.gov/29467239
https://pubmed.ncbi.nlm.nih.gov/29467239
Publikováno v:
Journal of Biological Chemistry. 289:5386-5398
Insulinomas (pancreatic islet β cell tumors) are the most common type of functioning pancreatic neuroendocrine tumors that occur sporadically or as a part of the MEN1 syndrome that is caused by germ line mutations in MEN1. Tissue-specific tumor pred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb29bc8194a44c0b2989509d06647bb
https://doi.org/10.1074/jbc.m113.533612
https://doi.org/10.1074/jbc.m113.533612