Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Vaishali Handa"'
1
LPS induces pp60c-src-mediated tyrosine phosphorylation of Hsp90 in lung vascular endothelial cells and mouse lung
Autor: Christiana Dimitropoulou, Sanjiv Kumar, Connie Snead, Stephen M. Black, Gagan Thangjam, Atul Joshi, David Fulton, Nektarios Barabutis, Vaishali Handa, Vijay Patel, John D. Catravas, Ruslan Rafikov
Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 304:L883-L893
Heat shock protein 90 (Hsp90) inhibitors were initially developed as anticancer agents; however, it is becoming increasing clear that they also possess potent anti-inflammatory properties. Posttranslational modifications of Hsp90 have been reported i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0b6c9a6c509bd12b1a26880e3526346
https://doi.org/10.1152/ajplung.00419.2012
Zobrazit plný text záznamu
2
The AUUCU Repeats Responsible for Spinocerebellar Ataxia Type 10 Form Unusual RNA Hairpins
Autor: Herman J.C. Yeh, Peter McPhie, Vaishali Handa, Karen Usdin
Publikováno v: Journal of Biological Chemistry. 280:29340-29345
Spinocerebellar ataxia type 10 is an autosomal dominant disorder caused by expansion of a pentameric repeat tract (ATTCT.AGAAT)(n) in intron 9 of the gene that encodes ataxin-10. We have analyzed duplex DNA containing the repeat, the individual DNA s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af31621d1394be556dbed746e4f3c7a4
https://doi.org/10.1074/jbc.m503495200
Zobrazit plný text záznamu
3
Long CGG-repeat tracts are toxic to human cells: Implications for carriers of Fragile X premutation alleles
Autor: Vaishali Handa, Margaret C. Cam, Karen Usdin, George Poy, Deena Goldwater, Daman Kumari, David Stiles
Publikováno v: FEBS Letters. 579:2702-2708
People with 59–200 CGG · CCG-repeats in the 5′ UTR of one of their FMR1 genes are at risk for Fragile X tremor and ataxia syndrome. Females are also at risk for premature ovarian failure. These symptoms are thought to be due to the presence of t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09f50d2ae7cb62593b4ab850bab2fa7
https://doi.org/10.1016/j.febslet.2005.04.004
Zobrazit plný text záznamu
4
The fragile X syndrome repeats form RNA hairpins that do not activate the interferon-inducible protein kinase, PKR, but are cut by Dicer
Autor: Tapas Saha, Vaishali Handa, Karen Usdin
Publikováno v: Nucleic Acids Research. 31:6243-6248
We show here that under physiologically reasonable conditions, CGG repeats in RNA readily form hairpins. In contrast to its DNA counterpart that forms a complex mixture of hairpins and tetraplexes, r(CGG)22 forms a single stable hairpin with no evide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb8dac86e6bf2a7c5bcfd417b655350b
https://doi.org/10.1093/nar/gkg818
Zobrazit plný text záznamu
6
Regulation of endothelial barrier function by TGF-beta type I receptor ALK5: Potential role of contractile mechanisms and heat shock protein 90
Autor: Alexander S. Antonov, Galina Antonova, John D. Catravas, Vaishali Handa, Peter ten Dijke, Makiko Fujii, Alexander D. Verin
Publikováno v: Journal of Cellular Physiology, 227(2), 759-771
Journal of Cellular Physiology
Multifunctional cytokine transforming growth factor-beta (TGF-β1) plays a critical role in the pathogenesis of acute lung inflammation by controlling endothelial monolayer permeability. TGF-β1 regulates endothelial cell (EC) functions via two disti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b0c541972e84b0c066924f7e312a49
https://hdl.handle.net/1887/117932
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje