Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Vaishali Bagalkot"'
Autor:
Kim, Sang Kyoon, Vaishali, Bagalkot, Lee, Eunhye, Lee, Seulki, Lee, Yong-kyu, Kumar, Tadiparthi Suresh, Moon, Hyun Tae, Byun, Youngro
Publikováno v:
In Thrombosis Research 2006 117(4):419-427
Autor:
Kim, Sang Kyoon, Lee, Eun Hye, Vaishali, Bagalkot, Lee, Seulki, Lee, Yong-kyu, Kim, Choong-Yong, Moon, Hyun Tae, Byun, Youngro
Publikováno v:
In Journal of Controlled Release 2005 105(1):32-42
Publikováno v:
Advanced Drug Delivery Reviews. 99:2-11
Clearance of apoptotic debris is a vital role of the innate immune system. Drawing upon principles of apoptotic clearance, convenient delivery vehicles including intrinsic anti-inflammatory characteristics and specificity to immune cells can be engin
Publikováno v:
Advanced Drug Delivery Reviews. 65:703-718
Nanoparticle-based drug delivery (NDD) has emerged as a promising approach to improving upon the efficacy of existing drugs and enabling the development of new therapies. Proof-of-concept studies have demonstrated the potential for NDD systems to sim
Autor:
Xiaohu Gao, Vaishali Bagalkot
Publikováno v:
ACS Nano. 5:8131-8139
SiRNA-aptamer chimeras are emerging as a highly promising approach for cell-type specific delivery of siRNA due to the outstanding targeting capability of aptamers and the compatibility of chimeras with native ribonuclease (Dicer) processing. For eff
Autor:
Robert Langer, Michael J. Cima, Philip W. Kantoff, Vaishali Bagalkot, Sangyong Jon, Mariam R Shaikh, Liangfang Zhang, Kai P. Yuet, Frank Alexis, Omid C. Farokhzad, Frank X. Gu, Neil H. Bander, Andrew Z. Wang, Christophoros C. Vasilliou
Publikováno v:
ChemMedChem. 3:1311-1315
ThemajorshortcomingofCombidexisitsinabilitytodetectPCadiseaseoutsideofthelymphnodes.Herein, we report the development of a novel, multifunc-tional, thermally cross-linked SPION (TCL-SPION) that can bothdetect PCa cells, and deliver targeted chemother
Autor:
Vaishali Bagalkot, Sangyong Jon, Liangfang Zhang, Robert Langer, Omid C. Farokhzad, Philip W. Kantoff, Etgar Levy-Nissenbaum
Publikováno v:
Nano Letters. 7:3065-3070
We report a novel quantum dot (QD)-aptamer(Apt)-doxorubicin (Dox) conjugate [QD-Apt(Dox)] as a targeted cancer imaging, therapy, and sensing system. By functionalizing the surface of fluorescent QD with the A10 RNA aptamer, which recognizes the extra
Autor:
Vaishali Bagalkot, Omid C. Farokhzad, Frank X. Gu, Liangfang Zhang, Aleksandar Filip Radovic-Moreno, Robert Langer, Frank Alexis, Pamela Basto, Sangyong Jon
Publikováno v:
ChemMedChem. 2:1268-1271
Apromisingapplicationofnanoparticle(NP)drugdeliverysystemsisthetargeteddeliveryoftherapeuticagentsinacell-,tissue-,ordisease-specificmanner.Thisgoalmaybeachieved by the surface-modification of NPs with antibodies,nucleic acid ligands (aptamers; Apt),
Autor:
Chaoneng Wu, Andrei Maiseyeu, Jeffrey A Deiuliis, Jixin Zhong, Xiaoquan Rao, Zhekang Ying, Vaishali Bagalkot, Sanjay Rajagopalan
Publikováno v:
Circulation. 132
Objective: Leptin has been previously shown to play an important role in maintaining insulin sensitivity and energy balance via catecholamine and cAMP dependent pathways. Since inhibition of phosphodiesterase 4 (PDE4), an enzyme that potently modulat
Autor:
Chaoneng Wu, Sanjay Rajagopalan, Zhekang Ying, Andrei Maiseyeu, Jixin Zhong, Vaishali Bagalkot, Xiaoquan Rao, Jeffrey A. Deiuliis
Publikováno v:
Circulation. 132
Objective: Recent evidence suggests an important role for cAMP-dependent pathways in modulation of innate immune function. Phosphodiesterase 4 (PDE4) is widely expressed in innate immune cells such as macrophages/dendritic cells with potent anti-infl