Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vaidrius Navikas"'
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 4, Pp 652-664 (2020)
Drug development guidelines from regulatory authorities provide important information to sponsors on requirements for clinical evidence needed to support approval of new drugs. In the field of Alzheimer’s disease (AD), recently published guidelines
Externí odkaz:
https://doaj.org/article/a67c500279614ef79f81ecf95f5c2079
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 4, Pp 652-664 (2020)
Clinical and Translational Science
Clinical and Translational Science
Drug development guidelines from regulatory authorities provide important information to sponsors on requirements for clinical evidence needed to support approval of new drugs. In the field of Alzheimer's disease (AD), recently published guidelines a
Publikováno v:
Immunology & Cell Biology. 88:468-476
IFN-beta is anticipated to have an important function in mucosal tolerance, as it is one of the major cytokines produced by plasmacytoid dendritic cells, and has recently been suggested as central to the maintenance of mucosal homeostasis. Here, we h
Publikováno v:
Journal of Allergy and Clinical Immunology. 111:550-557
Background: IFN-β has been shown to be effective as therapy for multiple sclerosis. Some reports attributed its beneficial effects to the capacity to induce a T H 2 response. However, other studies have suggested that endogenous type I IFN might dow
Publikováno v:
Respiratory Research, Vol 6, Iss 1, p 25 (2005)
Respiratory Research
Respiratory Research
Background CpG oligodeoxynucleotides (CpG-ODN) are capable of inducing high amounts of type I IFNs with many immunomodulatory properties. Furthermore, type-I IFNs have been proposed to play a key role in mediating effects of CpG-ODN. The precise role
Autor:
Alexandra Treschow, Shohreh Issazadeh-Navikas, Ingrid Teige, Tomas Leanderson, Rikard Holmdahl, Anna Teige, Vaidrius Navikas, Ragnar Mattsson
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 170(9)
Since the basic mechanisms behind the beneficial effects of IFN-β in multiple sclerosis (MS) patients are still obscure, here we have investigated the effects of IFN-β gene disruption on the commonly used animal model for MS, experimental autoimmun
Publikováno v:
Immunology & Cell Biology. 88:494-495
Publikováno v:
Journal of Allergy and Clinical Immunology. 109:S69-S69