Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Vaibhav Chikne"'
Autor:
Nofar Atari, K. Shanmugha Rajan, Vaibhav Chikne, Smadar Cohen-Chalamish, Tirza Doniger, Odelia Orbaum, Avi Jacob, Inna Kalt, Shulamit Michaeli, Ronit Sarid
Publikováno v:
Viruses, Vol 14, Iss 8, p 1720 (2022)
The nucleolus is a subnuclear compartment whose primary function is the biogenesis of ribosomal subunits. Certain viral infections affect the morphology and composition of the nucleolar compartment and influence ribosomal RNA (rRNA) transcription and
Externí odkaz:
https://doaj.org/article/8b4fc7ddcdbe421eb177c9e1f7f42875
Autor:
Samar Aramin, Rosi Fassler, Vaibhav Chikne, Mor Goldenberg, Tal Arian, Liat Kolet Eliaz, Oded Rimon, Oren Ram, Shulamit Michaeli, Dana Reichmann
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
ATP-independent chaperones are widespread across all domains of life and serve as the first line of defense during protein unfolding stresses. One of the known crucial chaperones for bacterial survival in a hostile environment (e.g., heat and oxidati
Externí odkaz:
https://doaj.org/article/b91bef5aaf77457cb479433f948516bc
Autor:
Dror Eliaz, Sriram Kannan, Hadassa Shaked, Gil Arvatz, Itai Dov Tkacz, Lior Binder, Hiba Waldman Ben-Asher, Uthman Okalang, Vaibhav Chikne, Smadar Cohen-Chalamish, Shulamit Michaeli
Publikováno v:
PLoS Pathogens, Vol 13, Iss 3, p e1006245 (2017)
Extracellular vesicles (EV) secreted by pathogens function in a variety of biological processes. Here, we demonstrate that in the protozoan parasite Trypanosoma brucei, exosome secretion is induced by stress that affects trans-splicing. Following per
Externí odkaz:
https://doaj.org/article/6d5be7b6dfff4aee9b63fbe6eef425a2
Autor:
Kathryn Decker, Moran Shalev-Benami, Ron Unger, Sachin Kumar Gupta, K. Shanmugha Rajan, Smadar Cohen-Chalamish, Elisabetta Ullu, Hava Madmoni, Tirza Doniger, Christian Tschudi, Vaibhav Chikne, Viplov Kumar Biswas, Shulamit Michaeli
Publikováno v:
Nucleic Acids Research
In trypanosomes, in contrast to most eukaryotes, the large subunit (LSU) ribosomal RNA is fragmented into two large and four small ribosomal RNAs (srRNAs) pieces, and this additional processing likely requires trypanosome-specific factors. Here, we e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6cc0b5c87434e95bb9c0a87ebe0c0b
https://doi.org/10.1093/nar/gky1287
https://doi.org/10.1093/nar/gky1287
Autor:
Shulamit Michaeli, Nofar Atari, Inna Kalt, Smadar Cohen-Chalamish, Avi Jacob, Odelia Orbaum, Vaibhav Chikne, Ronit Sarid, K. Shanmugha Rajan
The nucleolus is a sub-nuclear compartment whose primary function is the biogenesis of ribosomal subunits. Certain viral infections affect the morphology and composition of the nucleolar compartment and influence ribosomal RNA (rRNA) transcription an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06e0457c008069d742bcfb143e4e1f8c
https://doi.org/10.1101/2020.05.15.097808
https://doi.org/10.1101/2020.05.15.097808
Autor:
Tirza Doniger, Shulamit Michaeli, Smadar Cohen-Chalamish, Nikolay G. Kolev, Elisabetta Ullu, Nasreen Hag Yahia, Sachin Kumar Gupta, Christian Tschudi, Hiba Waldman Ben-Asher, Liat Kolet, Vaibhav Chikne, K. Shanmugha Rajan, Ron Unger
Publikováno v:
Journal of Molecular Biology. 429:3301-3318
The parasite Trypanosoma brucei is the causative agent of African sleeping sickness and is known for its unique RNA processing mechanisms that are common to all the kinetoplastidea including Leishmania and Trypanosoma cruzi. Trypanosomes possess two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07420ad1b6e987cea9a0edcc521528c
https://doi.org/10.1016/j.jmb.2017.04.015
https://doi.org/10.1016/j.jmb.2017.04.015
Autor:
Hiba Waldman Ben-Asher, K. Shanmugha Rajan, Kathryn Decker, Vaibhav Chikne, Shulamit Michaeli
Publikováno v:
Trends in parasitology. 35(10)
Trypanosomatids are protozoan parasites that cycle between an insect and a mammalian host. The large-subunit rRNA of these organisms undergoes unique processing events absent in other eukaryotes. Recently, small nucleolar RNAs (snoRNAs) that mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60c50d41c3483147201f5fa2f6dd5109
https://pubmed.ncbi.nlm.nih.gov/31473096
https://pubmed.ncbi.nlm.nih.gov/31473096
Autor:
Tirza Doniger, Doron Gerber, Oz Semo, Vaibhav Chikne, K. Shanmugha Rajan, Saurav Aryal, Smadar Cohen-Chalamish, Shulamit Michaeli, Christian Tschudi, Efrat Glick Saar, Ron Unger, Dana Chen
Publikováno v:
Nucleic Acids Research
The parasite Trypanosoma brucei, the causative agent of sleeping sickness, cycles between an insect and a mammalian host. Here, we investigated the presence of pseudouridines (Ψs) on the spliceosomal small nuclear RNAs (snRNAs), which may enable gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c000e7266621c9a401270818066a282e
https://pubmed.ncbi.nlm.nih.gov/31147702
https://pubmed.ncbi.nlm.nih.gov/31147702
Autor:
Hiba Waldman Ben-Asher, Lior Binder, Shulamit Michaeli, Gil Arvatz, Vaibhav Chikne, Uthman Okalang, Dror Eliaz, Sriram Kannan, Hadassa Shaked, Smadar Cohen-Chalamish, Itai Dov Tkacz
Publikováno v:
PLoS Pathogens, Vol 13, Iss 3, p e1006245 (2017)
PLoS Pathogens
PLoS Pathogens
Extracellular vesicles (EV) secreted by pathogens function in a variety of biological processes. Here, we demonstrate that in the protozoan parasite Trypanosoma brucei, exosome secretion is induced by stress that affects trans-splicing. Following per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92511f1123cf47c8b6d1ad3bacd91f1
http://europepmc.org/articles/PMC5352147?pdf=render
http://europepmc.org/articles/PMC5352147?pdf=render
Autor:
Shulamit Michaeli, Ilana Naboishchikov, Hiba Waldman Ben-Asher, Sachin Kumar Gupta, Dror Eliaz, Itai Dov Tkacz, Vaibhav Chikne, Shai Carmi
Publikováno v:
RNA Biology. 11:715-731
In trypanosomes, mRNAs are processed by trans-splicing; in this process, a common exon, the spliced leader, is added to all mRNAs from a small RNA donor, the spliced leader RNA (SL RNA). However, little is known regarding how this process is regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d312d6443f958ced7162b27fce61a0
https://doi.org/10.4161/rna.29143
https://doi.org/10.4161/rna.29143