Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Vahram Arakelov"'
Autor:
Nelli Muradyan, Vahram Arakelov, Arsen Sargsyan, Adrine Paronyan, Grigor Arakelov, Karen Nazaryan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The nucleocapsid (N) protein of SARS-CoV-2 is known to participate in various host cellular processes, including interferon inhibition, RNA interference, apoptosis, and regulation of virus life cycles. Additionally, it has potential as a dia
Externí odkaz:
https://doaj.org/article/0f75505402364d328b7d4436ee71250e
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221532 (2019)
Starting from 1972, colchicine is known as the most useful drug for prevention of familial Mediterranean fever attacks. However, some patients do not respond to colchicine treatment, even taken in high doses. Despite the fact, that different hypothes
Externí odkaz:
https://doaj.org/article/28a891bfefcc4c14b828922a1362eb72
Autor:
Mher Matevosyan, Vardan Harutyunyan, Narek Abelyan, Hamlet Khachatryan, Irina Tirosyan, Yeva Gabrielyan, Valter Sahakyan, Smbat Gevorgyan, Vahram Arakelov, Grigor Arakelov, Hovakim Zakaryan
Publikováno v:
Journal of biomolecular structuredynamics.
Influenza virus remains a major public health challenge due to its high morbidity and mortality and seasonal surge. Although antiviral drugs against the influenza virus are widely used as a first-line defense, the virus undergoes rapid genetic change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5161ec0fe3126c1d798792e6a7276b81
https://pubmed.ncbi.nlm.nih.gov/36541127
https://pubmed.ncbi.nlm.nih.gov/36541127
Autor:
Haifa E. Alsharari, Nasser Hadal Alotaibi, Mohamed A. Abdelgawad, Grigor Arakelov, Nouf Q. Albilasi, Mohammad M. Al-Sanea, Narek Abelyan, Harutyun Sahakyan, Vahram Arakelov, Abdulaziz A. S. Alsaleh, Atiah H. Almalki, Gharam M. Alazmi, Turki M. Alazmi, Garri Chilingaryan, Shaimaa Hussein, Faten S. Alruwaili, Karen Nazaryan, Tahani S. Alsharari, Waad M. Al-faraj
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Human carbonic anhydrase XII (hCA XII) isozyme is of high therapeutic value as a pharmacological target and biomarker for different types of cancer. The hCA XII is one of the crucial effectors that regulates extracellular and intracellular pH and aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952b361447b36e610a68f936d1af5f91
https://doaj.org/article/2c1d4ac6a4d343049a08b2c705fe9f50
https://doaj.org/article/2c1d4ac6a4d343049a08b2c705fe9f50
Autor:
Gharam M. Alazmi, Mohammad M. Al-Sanea, Turki M. Alazmi, Grigor Arakelov, Shaimaa Hussein, Nouf Q. Albilasi, Vahram Arakelov, Atiah H. Almalki, Tahani S. Alsharari, Narek Abelyan, Harutyun Sahakyan, Nasser Hadal Alotaibi, Mohamed A. Abdelgawad, Haifa E. Alsharari, Faten S. Alruwaili, Abdulaziz A. S. Alsaleh, Waad M. Al-faraj, Garri Chilingaryan
Human carbonic anhydrase XII (hCA XII) has gained therapeutic value in the field of medicinal chemistry as a pharmacological target and biomarker for different types of cancer. Despite the fact that interaction features of hCAs inhibitors with the ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::463c95ce6b6076cc2ebbb30782adbc2b
https://doi.org/10.21203/rs.3.rs-394808/v1
https://doi.org/10.21203/rs.3.rs-394808/v1
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 86:676-683
Pyrin protein is the product of the MEFV gene, mutations in which cause manifestation of familial Mediterranean fever (FMF). Functions of pyrin are not completely clear. The secondary structure of the pyrin is represented with four domains and two mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5791b52ec01df8b8d6312e5fa466ad6
https://doi.org/10.1002/prot.25494
https://doi.org/10.1002/prot.25494
Autor:
Fernando Ferreira, Harutyun Sahakyan, Erik Arabyan, Vahram Arakelov, Astghik Hakobyan, Karen Nazaryan, Armen Kotsinyan, Zaven Karalyan, Hovakim Zakaryan
Publikováno v:
Antiviral research. 167
African swine fever virus (ASFV) is the causative agent of an economically important disease of pigs for which no effective vaccines or antiviral drugs are available. Recent outbreaks in EU countries and China have highlighted the critical role of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ccfde7d2749e52a232b1556774ae10
https://pubmed.ncbi.nlm.nih.gov/30991087
https://pubmed.ncbi.nlm.nih.gov/30991087
Autor:
Hovakim Zakaryan, Zaven Karalyan, Astghik Hakobyan, Erik Arabyan, Vahram Arakelov, Anna Simonyan, Fernando Ferreira, Rouben Aroutiounian, Karen Nazaryan, Grigor Arakelov, Armen Kotsinyan
Publikováno v:
Antiviral Research
African swine fever virus (ASFV) is the causal agent of a highly-contagious and fatal disease of domestic pigs, leading to serious socio-economic consequences in affected countries. Once, neither an anti-viral drug nor an effective vaccines are avail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2bd298fa710c4593e123c17047b7a09
https://pubmed.ncbi.nlm.nih.gov/29940214
https://pubmed.ncbi.nlm.nih.gov/29940214
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 8, p e0221532 (2019)
PLoS ONE, Vol 14, Iss 8, p e0221532 (2019)
Starting from 1972, colchicine is known as the most useful drug for prevention of familial Mediterranean fever attacks. However, some patients do not respond to colchicine treatment, even taken in high doses. Despite the fact, that different hypothes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e294e15458ab82ffbb39627ed1b4443
https://doi.org/10.1371/journal.pone.0221532
https://doi.org/10.1371/journal.pone.0221532
Autor:
Sahakyan, Harutyun1, Abelyan, Narek1,2, Arakelov, Vahram1,2, Arakelov, Grigor1,2, Nazaryan, Karen1,2 karen.nazaryan@rau.am
Publikováno v:
PLoS ONE. 8/23/2019, Vol. 14 Issue 8, p1-9. 9p.