Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Vahitha B. Abdul-Salam"'
Autor:
Fisayo Olotu, Encarnacion Medina-Carmona, Angela Serrano-Sanchez, Felipe Ossa, Abdelaziz El-Hamdaoui, Özlem Tastan Bishop, Jose L. Ortega-Roldan, Vahitha B. Abdul-Salam
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 688-701 (2023)
The use of computer-aided methods have continued to propel accelerated drug discovery across various disease models, interestingly allowing the specific inhibition of pathogenic targets. Chloride Intracellular Channel Protein 4 (CLIC4) is a novel cla
Externí odkaz:
https://doaj.org/article/6eee98be897b4998ba4e965cd2a5c06a
Autor:
Giusy Russomanno, Kyeong Beom Jo, Vahitha B. Abdul-Salam, Claire Morgan, Jens Endruschat, Ute Schaeper, Ahmed H. Osman, Mai M. Alzaydi, Martin R. Wilkins, Beata Wojciak-Stothard
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 142-153 (2021)
Circulating levels of endothelial miR-150 are reduced in pulmonary arterial hypertension (PAH) and act as an independent predictor of patient survival, but links between endothelial miR-150 and vascular dysfunction are not well understood. We studied
Externí odkaz:
https://doaj.org/article/1ef7e3ae6a3743cb92c264e332ebbdb8
Autor:
Hebah A. Sindi, Giusy Russomanno, Sandro Satta, Vahitha B. Abdul-Salam, Kyeong Beom Jo, Basma Qazi-Chaudhry, Alexander J. Ainscough, Robert Szulcek, Harm Jan Bogaard, Claire C. Morgan, Soni S. Pullamsetti, Mai M. Alzaydi, Christopher J. Rhodes, Roberto Piva, Christina A. Eichstaedt, Ekkehard Grünig, Martin R. Wilkins, Beata Wojciak-Stothard
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Pulmonary arterial hypertension is a severe lung disease characterised by progressive vascular remodelling. Here, the authors show that reduced signalling of flow-activated transcription factor KLF2 is a common feature of human PAH and that KLF2-regu
Externí odkaz:
https://doaj.org/article/4eebb969beec4b25a1d7906be6c74e47
Autor:
Hebah A. Sindi, Giusy Russomanno, Sandro Satta, Vahitha B. Abdul-Salam, Kyeong Beom Jo, Basma Qazi-Chaudhry, Alexander J. Ainscough, Robert Szulcek, Harm Jan Bogaard, Claire C. Morgan, Soni S. Pullamsetti, Mai M. Alzaydi, Christopher J. Rhodes, Roberto Piva, Christina A. Eichstaedt, Ekkehard Grünig, Martin R. Wilkins, Beata Wojciak-Stothard
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/fa8a888d88b04f9885e436a2355e805e
Autor:
Fisayo Olotu, Encarnacion Medina-Carmona, Angela Serrano-Sanchez, Felipe Ossa, Abdelaziz El-Hamdaoui, Özlem Tastan Bishop, Jose L. Ortega-Roldan, Vahitha B. Abdul-Salam
Supplementary data associated with this article can be found in the online version at doi:10.1016/j.csbj.2022.12.040.
Acknowledgment We would like to thank the Center for High-Performance Computing, Cape Town, South Africa for providing computat
Acknowledgment We would like to thank the Center for High-Performance Computing, Cape Town, South Africa for providing computat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7854f354b368eb2db4da2344c0230c96
https://hdl.handle.net/10481/80036
https://hdl.handle.net/10481/80036
Autor:
Sunday O. Olatunji, Abdussalam Alshehri, Abdullah Alqahtani, Abdullah M. Almuhaideb, Mohammed Alshahrani, Waad Sami O Atiyah, Nahier Aldhafferi, Subhodeep Dey, Fatema S. Shaikh, Saema Abdulhamid, Sara Mhd. Bachar Chrouf, Yousof Zohair Almunsour, Areej Buker, Dalal Ali Mahaii AlBuhairi, Raha Saud Abdulaziz Alkabour, Vahitha B Abdul-Salam
Publikováno v:
Journal of Multidisciplinary Healthcare
Fatema S Shaikh,1 Nahier Aldhafferi,1 Areej Buker,1 Abdullah Alqahtani,1 Subhodeep Dey,2 Saema Abdulhamid,1 Dalal Ali Mahaii AlBuhairi,1 Raha Saud Abdulaziz Alkabour,1 Waad Sami O Atiyah,1 Sara Bachar Chrouf,1 Abdussalam Alshehri,3 Sunday Olusanya Ol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06cbf041c7225e413eafb67d12648ae
https://doi.org/10.2147/jmdh.s317884
https://doi.org/10.2147/jmdh.s317884
Autor:
Beata Wojciak-Stothard, Vahitha B. Abdul-Salam, Giuseppe Faggian, Michele Miragoli, Roman Y. Medvedev, Julia Gorelik, Anita Alvarez-Laviada, Jose L. Sanchez-Alonso, Eef Dries, Natalia A. Trayanova, Stefano Rossi, Tilo Schorn
Publikováno v:
Hypertension
Pulmonary hypertension is a complex disorder characterized by pulmonary vascular remodeling and right ventricular hypertrophy, leading to right heart failure. The mechanisms underlying this process are not well understood. We hypothesize that the str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69749498ed5a496fdcd1a460bb090727
https://doi.org/10.1161/hypertensionaha.120.14858
https://doi.org/10.1161/hypertensionaha.120.14858
Autor:
Fisayo Olotu, Encarnacion Medina-Carmona, Abdelaziz El-Hamdaoui, Özlem Tastan Bishop, Jose L. Ortega-Roldan, Vahitha B. Abdul-Salam
Chloride Intracellular Channel Protein 4 (CLIC4) is a novel class of intracellular ion channel highly implicated in tumour and vascular biology. It regulates cell proliferation, apoptosis and angiogenesis; and is involved in multiple pathologic signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bde7ccf0c661dce55712da9d98ff1827
https://doi.org/10.1101/2022.04.21.489122
https://doi.org/10.1101/2022.04.21.489122
Autor:
Jens Endruschat, Claire Morgan, Martin R. Wilkins, Ahmed H. Osman, Beata Wojciak-Stothard, Giusy Russomanno, Mai M. Alzaydi, Kyeong Beom Jo, Ute Schaeper, Vahitha B. Abdul-Salam
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 23, Iss, Pp 142-153 (2021)
MOLECULAR THERAPY-NUCLEIC ACIDS
Molecular Therapy: Nucleic Acids, Vol 23, Iss, Pp 142-153 (2021)
MOLECULAR THERAPY-NUCLEIC ACIDS
Circulating levels of endothelial miR-150 are reduced in pulmonary arterial hypertension (PAH) and act as an independent predictor of patient survival, but links between endothelial miR-150 and vascular dysfunction are not well understood. We studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e85508e36a8368394eb31071187ddae
http://europepmc.org/articles/PMC7733016
http://europepmc.org/articles/PMC7733016
Autor:
Sandro Satta, Christopher J. Rhodes, Kyeong Beom Jo, Hebah A. Sindi, Martin R. Wilkins, Mai M. Alzaydi, Alexander J. Ainscough, Basma Qazi-Chaudhry, Harm Jan Bogaard, Giusy Russomanno, Beata Wojciak-Stothard, Soni Savai Pullamsetti, Robert Szulcek, Claire Morgan, Roberto Piva, Christina A. Eichstaedt, Ekkehard Grünig, Vahitha B. Abdul-Salam
Publikováno v:
Nature Communications, 11(1):1185. Nature Publishing Group UK
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
NATURE COMMUNICATIONS
Sindi, H A, Russomanno, G, Satta, S, Abdul-Salam, V B, Jo, K B, Qazi-Chaudhry, B, Ainscough, A J, Szulcek, R, Jan Bogaard, H, Morgan, C C, Pullamsetti, S S, Alzaydi, M M, Rhodes, C J, Piva, R, Eichstaedt, C A, Grünig, E, Wilkins, M R & Wojciak-Stothard, B 2020, ' Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension ', Nature Communications, vol. 11, no. 1, 1185 . https://doi.org/10.1038/s41467-020-14966-x
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
NATURE COMMUNICATIONS
Sindi, H A, Russomanno, G, Satta, S, Abdul-Salam, V B, Jo, K B, Qazi-Chaudhry, B, Ainscough, A J, Szulcek, R, Jan Bogaard, H, Morgan, C C, Pullamsetti, S S, Alzaydi, M M, Rhodes, C J, Piva, R, Eichstaedt, C A, Grünig, E, Wilkins, M R & Wojciak-Stothard, B 2020, ' Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension ', Nature Communications, vol. 11, no. 1, 1185 . https://doi.org/10.1038/s41467-020-14966-x
Nature Communications
Pulmonary arterial hypertension (PAH) is a severe disorder of lung vasculature that causes right heart failure. Homoeostatic effects of flow-activated transcription factor Krüppel-like factor 2 (KLF2) are compromised in PAH. Here, we show that KLF2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff2d0f7a264a7a3a9a16f23e72f3402b
https://research.vumc.nl/en/publications/049dd2cd-5692-4828-b334-1f78c2e52991
https://research.vumc.nl/en/publications/049dd2cd-5692-4828-b334-1f78c2e52991