Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Vahid H. Gazestani"'
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 2, p e0005368 (2017)
Trypanosomatid parasites cause serious infections in humans and production losses in livestock. Due to the high divergence from other eukaryotes, such as humans and model organisms, the functional roles of many trypanosomatid proteins cannot be predi
Externí odkaz:
https://doaj.org/article/e1945c5a7f07442a83e14ba706895703
Autor:
Vahid H Gazestani, Najmeh Nikpour, Vaibhav Mehta, Hamed S Najafabadi, Houtan Moshiri, Armando Jardim, Reza Salavati
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 3, p e0004533 (2016)
The functions of the majority of trypanosomatid-specific proteins are unknown, hindering our understanding of the biology and pathogenesis of Trypanosomatida. While protein-protein interactions are highly informative about protein function, a global
Externí odkaz:
https://doaj.org/article/163a076614284ffc9c954b8388182b0b
Autor:
Bokan Bao, Javad Zahiri, Vahid H. Gazestani, Linda Lopez, Yaqiong Xiao, Raphael Kim, Teresa H. Wen, Austin W. T. Chiang, Srinivasa Nalabolu, Karen Pierce, Kimberly Robasky, Tianyun Wang, Kendra Hoekzema, Evan E. Eichler, Nathan E. Lewis, Eric Courchesne
Publikováno v:
Molecular psychiatry, vol 28, iss 2
Autism Spectrum Disorder (ASD) diagnosis remains behavior-based and the median age of diagnosis is ~52 months, nearly 5 years after its first-trimester origin. Accurate and clinically-translatable early-age diagnostics do not exist due to ASD genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc1f048c8ff68350b23dcf02eba0a2c
https://pubmed.ncbi.nlm.nih.gov/36266569
https://pubmed.ncbi.nlm.nih.gov/36266569
Autor:
Vahid H Gazestani, Reza Salavati
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142342 (2015)
Trypanosoma brucei is a vector-borne parasite with intricate life cycle that can cause serious diseases in humans and animals. This pathogen relies on fine regulation of gene expression to respond and adapt to variable environments, with implications
Externí odkaz:
https://doaj.org/article/eb773de2f67e4f88b23c0e427c953a0d
Autor:
Kim R, Nathan E. Lewis, Vahid H. Gazestani, Austin W. T. Chiang, Yaqiong Xiao, Karen Pierce, Bokan Bao, Srinivasa Nalabolu, Kimberly Robasky, Eric Courchesne
ImportanceASD diagnosis remains behavior-based and the median age of the first diagnosis remains unchanged at ∼52 months, which is nearly 5 years after its first trimester origin. Long delays between ASD’s prenatal onset and eventual diagnosis li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffa6c8faa135f99d73dbb0c8624487db
https://doi.org/10.1101/2021.07.08.21260225
https://doi.org/10.1101/2021.07.08.21260225
Autor:
Linda Lopez, Eric Courchesne, Tiziano Pramparo, Sarah S. Murray, Benjamin P. Kellman, Nathan E. Lewis, Vahid H. Gazestani, Srinivasa Nalabolu, Karen Pierce
Publikováno v:
Nature neuroscience
Hundreds of genes are implicated in autism spectrum disorder (ASD) but the mechanisms through which they contribute to ASD pathophysiology remain elusive. Here, we analyzed leukocyte transcriptomics from 1-4 year-old male toddlers with ASD or typical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1351b048a97c7f46b9c8b837ed60bf
http://europepmc.org/articles/PMC6764590
http://europepmc.org/articles/PMC6764590
Autor:
Vahid H. Gazestani, Nathan E. Lewis
Publikováno v:
Curr Opin Syst Biol
Cells, as complex systems, consist of diverse interacting biomolecules arranged in dynamic hierarchical modules. Recent advances in deep learning methods now allow one to encode this rich existing knowledge in the architecture of the learning procedu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71deea2ec675524ebb8ef8f2aa1ad49c
https://doi.org/10.1016/j.coisb.2019.04.001
https://doi.org/10.1016/j.coisb.2019.04.001
Autor:
Srinivasa Nalabolu, Tiziano Pramparo, Benjamin P. Kellman, Vahid H. Gazestani, Eric Courchesne, Sarah S. Murray, Shangzhong Li, Hratch M. Baghdassarian, Arjana Begzati, Karen Pierce, Nathan E. Lewis, Isaac Shamie, Linda Lopez
Publikováno v:
BMC Genomics
BMC genomics, vol 22, iss 1
BMC Genomics, Vol 22, Iss 1, Pp 1-15 (2021)
BMC genomics, vol 22, iss 1
BMC Genomics, Vol 22, Iss 1, Pp 1-15 (2021)
Background Both RNA-Seq and sample freeze-thaw are ubiquitous. However, knowledge about the impact of freeze-thaw on downstream analyses is limited. The lack of common quality metrics that are sufficiently sensitive to freeze-thaw and RNA degradation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8abb7ef130364b83f47dec0df4d465
https://doi.org/10.1186/s12864-021-07381-z
https://doi.org/10.1186/s12864-021-07381-z
Autor:
Vahid H. Gazestani, Debra Cha, Elizabeth Bacon, Terri Cook-Clark, Linda Lopez, Eric Courchesne, Kim Gaines, Srinivasa Nalabolu, Amanda Cheng, Cynthia Carter Barnes, Kathy Karins, Gohar Gyurjyan, Karen Pierce, Christie Pham, Steven Arias
Publikováno v:
The Journal of pediatrics. 236
Objectives To examine the impact of a new approach, Get SET Early, on the rates of early autism spectrum disorder (ASD) detection and factors that influence the screen-evaluate-treat chain. Study design After attending Get SET Early training, 203 ped
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9948db4c57ae0fcb0e30fab7ba30e291
https://pubmed.ncbi.nlm.nih.gov/33915154
https://pubmed.ncbi.nlm.nih.gov/33915154
Autor:
Eric Courchesne, Tiziano Pramparo, Elizabeth Bacon, Cynthia Carter Barnes, Michael V. Lombardo, Natasha Bertelsen, Linda Lopez, Vahid H. Gazestani, Karen Pierce, Elena Maria Busuoli, Aubyn C. Stahmer, Laura Schreibman, Isotta Landi, Veronica Mandelli
Early detection and intervention are believed to be key to facilitating better outcomes in children with autism, yet the impact of age at treatment start on outcome is poorly understood. While clinical traits such as language ability have been shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b8b259607dbce3307cdc77b4b7d247a
https://doi.org/10.1101/2020.12.21.20248674
https://doi.org/10.1101/2020.12.21.20248674