Výsledky vyhledávání

A hydrogel platform for co‐delivery of immunomodulatory proteins for pancreatic islet allografts

Autor: Juan D, Medina, Graham F, Barber, Maria M, Coronel, Michael D, Hunckler, Stephen W, Linderman, Michelle J, Quizon, Vahap, Ulker, Esma S, Yolcu, Haval, Shirwan, Andrés J, García

Publikováno v: Journal of Biomedical Materials Research Part A. 110:1728-1737

Type 1 diabetes (T1D), an autoimmune disorder in which the insulin-producing β-cells in the islets of Langerhans in the pancreas are destroyed, afflicts over 1.6 million Americans. Although pancreatic islet transplantation has shown promise in treat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22dc73bb240a86158a9c0f510b1b2652
https://doi.org/10.1002/jbm.a.37429

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Abstract A007: Assessing immunoprevention efficacy of an agonist of CD137 pathway in a tobacco carcinogen-induced lung cancer preclinical model

Autor: Ayse Ece Gulen, Mohammad Tarique, Vahap Ulker, Evrim Agca, Haval Shirwan, Esma S. Yolcu

Publikováno v: Cancer Prevention Research. 15:A007-A007

Purpose: Lung cancer is the leading cause of cancer-related deaths worldwide. Cigarette smoking is the primary risk factor for lung cancer and is linked to 80-90% of lung cancer deaths according to the Centers for Disease Control (CDC). The most carc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e69d106f068cecbc4c194aa24c6f0d0
https://doi.org/10.1158/1940-6215.tacpad22-a007

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FasL microgels induce immune acceptance of islet allografts in nonhuman primates

Publikováno v: Science advances. 8(19)

Islet transplantation to treat insulin-dependent diabetes is greatly limited by the need for maintenance immunosuppression. We report a strategy through which cotransplantation of allogeneic islets and streptavidin (SA)–FasL–presenting microgels

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aded5a5445852b3a900f73d8700fe42
https://pubmed.ncbi.nlm.nih.gov/35559682

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Akademický článek

Prime-boost vaccination with SA-4-1BBL costimulatory molecule and survivin eradicates lung carcinoma in CD8+ T and NK cell dependent manner.

Autor: Abhishek K Srivastava, Rajesh K Sharma, Esma S Yolcu, Vahap Ulker, Kathryn MacLeod, Gunes Dinc, Haval Shirwan

Publikováno v: PLoS ONE, Vol 7, Iss 11, p e48463 (2012)

Subunit vaccines containing universal tumor associated antigens (TAAs) present an attractive treatment modality for cancer primarily due to their safety and potential to generate long-term immunological responses that can safeguard against recurrence

Externí odkaz: https://doaj.org/article/ada9d8891aa4404995a7a5b010953096

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