Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Vahan Simonyan"'
Autor:
Laura Elisabeth Gressler, Terrie Cowley, Marti Velezis, Suvekshya Aryal, Deanne Clare, John W. Kusiak, Allen W. Cowley, Art Sedrakyan, Danica Marinac-Dabic, Michelle Reardon, Lisa Schmidt, Jennifer Ginsburg Feldman, Vincent DiFabio, Suzie Bergman, Vahan Simonyan, Yelena Yesha, Ingrid Vasiliu-Feltes, Justin Durham, Andrew I. Steen, Phillip Woods, Flavia P. Kapos, Nilsa Loyo-Berrios
Publikováno v:
Frontiers in Digital Health, Vol 5 (2023)
BackgroundConflicting reports from varying stakeholders related to prognosis and outcomes following placement of temporomandibular joint (TMJ) implants gave rise to the development of the TMJ Patient-Led RoundTable initiative. Following an assessment
Externí odkaz:
https://doaj.org/article/192a9103aaf845cf829420f0aa6c0062
Autor:
Wen-Wei Zhang, Subir Karmakar, Sreenivas Gannavaram, Ranadhir Dey, Patrick Lypaczewski, Nevien Ismail, Abid Siddiqui, Vahan Simonyan, Fabiano Oliveira, Iliano V. Coutinho-Abreu, Thiago DeSouza-Vieira, Claudio Meneses, James Oristian, Tiago D. Serafim, Abu Musa, Risa Nakamura, Noushin Saljoughian, Greta Volpedo, Monika Satoskar, Sanika Satoskar, Pradeep K. Dagur, J. Philip McCoy, Shaden Kamhawi, Jesus G. Valenzuela, Shinjiro Hamano, Abhay R. Satoskar, Greg Matlashewski, Hira L. Nakhasi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Here, the authors engineer an attenuated knock-out Leishmania (LmCen −/−) vaccine that is safe in immunocompromised mice and induces an immune response and protection similar to leishmanization with wild-type Leishmania. Since LmCen −/− is an
Externí odkaz:
https://doaj.org/article/a50605a064c049859dfcd1fb76a10dad
Autor:
Stefan Dabic, Yasameen Azarbaijani, Tigran Karapetyan, Nilsa Loyo‐Berrios, Vahan Simonyan, Terrie Kitchner, Murray Brilliant, Yelizaveta Torosyan
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 1, Pp 98-109 (2020)
Translational multidisciplinary research is important for the Center for Devices and Radiological Health's efforts for utilizing real‐world data (RWD) to enhance predictive evaluation of medical device performance in patient subpopulations. As part
Externí odkaz:
https://doaj.org/article/357d1b0b6b814fcc8590878689c69065
Autor:
Lai Xu, Helen Luo, Rong Wang, Wells W. Wu, Je-Nie Phue, Rong-Fong Shen, Hartmut Juhl, Leihong Wu, Wei-lun Alterovitz, Vahan Simonyan, Lorraine Pelosof, Amy S. Rosenberg
Publikováno v:
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Reference genes are often interchangeably called housekeeping genes due to 1) the essential cellular functions their proteins provide and 2) their constitutive expression across a range of normal and pathophysiological conditions.
Externí odkaz:
https://doaj.org/article/4139dfba11ea48ae9b6493a2f0e9f38d
Autor:
Bhavna Hora, Naila Gulzar, Yue Chen, Konstantinos Karagiannis, Fangping Cai, Chang Su, Krista Smith, Vahan Simonyan, Sharaf Ali Shah, Manzoor Ahmed, Ana M. Sanchez, Mars Stone, Myron S. Cohen, Thomas N. Denny, Raja Mazumder, Feng Gao
Publikováno v:
mSphere, Vol 5, Iss 5 (2020)
ABSTRACT High-throughput sequencing (HTS) has been widely used to characterize HIV-1 genome sequences. There are no algorithms currently that can directly determine genotype and quasispecies population using short HTS reads generated from long genome
Externí odkaz:
https://doaj.org/article/ad53339e65e5434399222e31b258226c
Autor:
John Athey, Aikaterini Alexaki, Ekaterina Osipova, Alexandre Rostovtsev, Luis V. Santana-Quintero, Upendra Katneni, Vahan Simonyan, Chava Kimchi-Sarfaty
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract Background Due to the degeneracy of the genetic code, most amino acids can be encoded by multiple synonymous codons. Synonymous codons naturally occur with different frequencies in different organisms. The choice of codons may affect protein
Externí odkaz:
https://doaj.org/article/8465e5709807407f9bb996393f34ae42
Autor:
Sreenivas Gannavaram, John Torcivia, Lusine Gasparyan, Amit Kaul, Nevien Ismail, Vahan Simonyan, Hira L. Nakhasi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract No licensed human vaccines are currently available against leishmaniasis. Several anti-leishmanial vaccines are currently undergoing testing, including genetically modified live-attenuated parasite vaccines. Studies with live attenuated Leis
Externí odkaz:
https://doaj.org/article/d976c0ed5ec047e4a8b50c73f5058f1b
Autor:
Trent J Bosma, Konstantinos Karagiannis, Luis Santana-Quintero, Natalia Ilyushina, Tatiana Zagorodnyaya, Svetlana Petrovskaya, Majid Laassri, Raymond P Donnelly, Steven Rubin, Vahan Simonyan, Christian J Sauder
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216944 (2019)
Most viruses are known to spontaneously generate defective viral genomes (DVG) due to errors during replication. These DVGs are subgenomic and contain deletions that render them unable to complete a full replication cycle in the absence of a co-infec
Externí odkaz:
https://doaj.org/article/21d18c0f908a4ec790262c8d12cf6b0a
Autor:
Ashley D Smith, Elissa D Foss, Irma Zhang, Jessica L Hastie, Nicole P Giordano, Lusine Gasparyan, Lam Phuc VinhNguyen, Alyxandria M Schubert, Deepika Prasad, Hannah L McMichael, Jinchun Sun, Richard D Beger, Vahan Simonyan, Siobhán C Cowley, Paul E Carlson
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0223025 (2019)
Clostridium difficile (Cd) infection (CDI) typically occurs after antibiotic usage perturbs the gut microbiota. Mucosa-associated invariant T cells (MAIT) are found in the gut and their development is dependent on Major histocompatibility complex-rel
Externí odkaz:
https://doaj.org/article/6661098026ec44cda89025df50cdf9de
Autor:
Charles H King, Hiral Desai, Allison C Sylvetsky, Jonathan LoTempio, Shant Ayanyan, Jill Carrie, Keith A Crandall, Brian C Fochtman, Lusine Gasparyan, Naila Gulzar, Paul Howell, Najy Issa, Konstantinos Krampis, Lopa Mishra, Hiroki Morizono, Joseph R Pisegna, Shuyun Rao, Yao Ren, Vahan Simonyan, Krista Smith, Sharanjit VedBrat, Michael D Yao, Raja Mazumder
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0206484 (2019)
A comprehensive knowledge of the types and ratios of microbes that inhabit the healthy human gut is necessary before any kind of pre-clinical or clinical study can be performed that attempts to alter the microbiome to treat a condition or improve the
Externí odkaz:
https://doaj.org/article/f1404c71905a4888a51f757bd3a82748