Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Vagmita Pabuwal"'
Autor:
Tzintzuni I Garcia, Isa Matos, Yingjia Shen, Vagmita Pabuwal, Maria Manuela Coelho, Yuko Wakamatsu, Manfred Schartl, Ronald B Walter
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100250 (2014)
Assessing allele-specific gene expression (ASE) on a large scale continues to be a technically challenging problem. Certain biological phenomena, such as X chromosome inactivation and parental imprinting, affect ASE most drastically by completely shu
Externí odkaz:
https://doaj.org/article/b166183400e948aca7935a061d24f7fe
Autor:
Vagmita Pabuwal, Mikki Boswell, Amanda Pasquali, Sandra S. Wise, Suresh Kumar, Yingjia Shen, Tzintzuni Garcia, Carolyne LaCerte, John Pierce Wise, Wesley Warren, Ronald B. Walter
Publikováno v:
Aquatic Toxicology. :74-81
Hexavalent chromium Cr(VI) is known to produce cytotoxic effects in humans and is a highly toxic environmental contaminant. Interestingly, it has been shown that free ranging sperm whales (Phyester macrocephalus) may have exceedingly high levels of C
Autor:
Vagmita Pabuwal, Zhijun Li
Publikováno v:
Biopolymers. 95:31-38
Seven-helix transmembrane proteins, including the G-protein coupled receptors, mediate a broad range of fundamental cellular activities through binding to a wide range of ligands. Understanding the structural basis for the ligand-binding selectivity
Publikováno v:
Current Proteomics. 5:181-190
Autor:
Yingjia Shen, Tzintzuni Garcia, Ronald B. Walter, Wes Warren, Vagmita Pabuwal, Amanda Pasquali, William A. Cresko, Mikki Boswell, Manfred Schartl, Ion Beldorth
In recent years RNA-Seq technology has been used not only to quantify differences in gene expression but also to understand the underlying mechanisms that lead to these differences. Nucleotide sequence variation arising through evolution may differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b46051b253cb3e54fa2e8bcb58c81e7
https://europepmc.org/articles/PMC3746558/
https://europepmc.org/articles/PMC3746558/
Autor:
Vagmita Pabuwal, Zhijun Li
Publikováno v:
Protein engineering, designselection : PEDS. 22(2)
Elucidating the distinct topology of residue packing in transmembrane proteins is essential for developing high-quality computational tools for their structure prediction. Network approaches transforming a protein's three-dimensional structure into a
Autor:
Zhijun Li, Vagmita Pabuwal
Publikováno v:
Protein engineering, designselection : PEDS. 21(1)
De novo protein structure prediction plays an important role in studies of helical membrane proteins as well as structure-based drug design efforts. Developing an accurate scoring function for protein structure discrimination and validation remains a
Autor:
Yingjia Shen, I. Matos, Manfred Schartl, Vagmita Pabuwal, Tzintzuni Garcia, Wakamatsu Yuko, Ronald B. Walter, Maria M. Coelho
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100250 (2014)
PLoS ONE
PLoS ONE
Assessing allele-specific gene expression (ASE) on a large scale continues to be a technically challenging problem. Certain biological phenomena, such as X chromosome inactivation and parental imprinting, affect ASE most drastically by completely shu
Autor:
Vagmita Pabuwal, Zhijun Li
Publikováno v:
Biophysical Journal. (3):9a
Seven-helix transmembrane proteins, including the G-protein coupled receptors, mediate a broad range of fundamental cellular activities through binding to a wide range of ligands. Understanding the structural basis for the ligand-binding selectivity
Publikováno v:
Biophysical Journal. (3):203a
Transmembrane (TM) proteins are estimated to account for ∼20-30% of the human genome and serve as important drug targets. Despite the significant progress in experimental techniques, TM protein structure determination remains a challenge in general