Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Vadithe, Lakshma Nayak"'
Autor:
Tunki, Lakshmi a, c, Kulhari, Hitesh b, Vadithe, Lakshma Nayak a, Kuncha, Madhusudana a, Bhargava, Suresh c, Pooja, Deep a, ⁎, Sistla, Ramakrishna a, ⁎
Publikováno v:
In European Journal of Pharmaceutical Sciences 1 September 2019 137
Autor:
Chitrakar, Ravi a, Rawat, Deepa a, Sistla, Ramakrishna b, ⁎, Vadithe, Lakshma Nayak b, Subbarayappa, Adimurthy a, ⁎
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1 October 2021 49
Autor:
Abdullah Alarifi, Ahmed Kamal, Syed Mohammed Ali Hussaini, B. Sridevi, Faria Sultana, Siddiq Pasha Shaik, Debanjan Bhattacharjee, Vadithe Lakshma Nayak, Kanakaraju Marumudi, Thokhir Basha Shaik
Publikováno v:
ChemistrySelect. 2:9901-9910
A series of 2-anilinopyridyl linked oxindole conjugates (6 a-ad) were synthesized andevaluated for their antiproliferative activity against a panel of four human cancer cell lines viz., HeLa, DU-145, A549 and MCF-7. All the compounds showed very good
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff54e07500bda49c8e279e51007eeb26
https://doi.org/10.1002/slct.201701787
https://doi.org/10.1002/slct.201701787
Publikováno v:
Chemical Biology & Drug Design. 91:220-233
A series of novel menadione-based triazole hybrids were designed and synthesized by employing copper-catalyzed azide-alkyne cycloaddition (CuAAC). All the synthesized hybrids were characterized by their spectral data (1 H NMR, 13 C NMR, IR, and HRMS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a4cbb5190ddd4cf4066e94fe098a35
https://doi.org/10.1111/cbdd.13073
https://doi.org/10.1111/cbdd.13073
Autor:
Madasu Chandrashekhar, Uppuluri Venkata Mallavadhani, Vadithe Lakshma Nayak, Sistla Ramakrishna
Publikováno v:
European Journal of Medicinal Chemistry. 114:293-307
The 3-keto functionality in ring A of myrrhanone C, a natural bicyclic triterpene has been chemically modified and synthesized 27 novel triazole hybrids belonging to two different series in very good to excellent yields (66-83%). The synthesized comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3134c5243a2f1c632aa3d38dcbea2e2
https://doi.org/10.1016/j.ejmech.2016.03.013
https://doi.org/10.1016/j.ejmech.2016.03.013
Autor:
Narayana Nagesh, Vadithe Lakshma Nayak, Nandhagopal Raja, Gajendra Gupta, Bruno Therrien, Neelakandan Devika, Ahmed Kamal
Publikováno v:
Journal of Organometallic Chemistry. 794:104-114
Pyrenyl-derived thiosemicarbazone half-sandwich complexes of the types [(η6-p-MeC6H4Pri)Ru(Ln)Cl]+ and [(η5-C5Me5)M(Ln)Cl]+ (M = Rh, Ir; L1 = pyrenecarboxaldehyde-3-thiosemicarbazone, L2 = pyrenecarboxaldehyde-4-methyl-3-thiosemicarbazone, L3 = pyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cba62b94763929b2924bf39d05a64f0e
https://doi.org/10.1016/j.jorganchem.2015.06.036
https://doi.org/10.1016/j.jorganchem.2015.06.036
Autor:
Balasubramanian Sridhar, Vadithe Lakshma Nayak, Feroz Khan, Kakaraparthi Pandu Sastry, Kvn Satya Srinivas, Ponnam Devendar, Jonnala Kotesh Kumar, Sistla Ramakrishna, Dharmendra Kumar Yadav, Arigari Niranjana Kumar
Publikováno v:
MedChemComm. 6:898-904
A series of 3,19-O-acetal derivatives of andrographolide (1) have been synthesized by protecting the hydroxyls at C-3 and C-19 through a novel route. All the derivatives were evaluated for in vitro anticancer activity. Among the synthesized derivativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbdd5e26cde57da8390c677e62188e10
https://doi.org/10.1039/c4md00566j
https://doi.org/10.1039/c4md00566j
Autor:
Jedy Jose, Ahmed Kamal, Vadithe Lakshma Nayak, Korrapati Suresh Babu, Prema L. Mallipeddi, Kunta Chandra Shekar, Rasala Mahesh, Thokhir Basha Shaik, Syed Riyaz, Gajjela Bharth Kumar, Narayana Nagesh, Challa Ratna Reddy
Publikováno v:
ChemMedChem. 12(9)
Newer therapeutics can be developed in drug discovery by adopting the strategy of scaffold hopping of the privileged scaffolds from known bioactive compounds. This strategy has been widely employed in drug-discovery processes. Structure-based docking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55be2a7affb56dc6ecef59f3e39b51d
https://pubmed.ncbi.nlm.nih.gov/28276645
https://pubmed.ncbi.nlm.nih.gov/28276645
Publikováno v:
Bioorganic chemistry. 68
Ring-C of oleanolic acid was chemically modified by treating with NBS under a variety of experimental conditions. The structures of the synthesized compounds were established by spectral analysis (1H &13C NMR and Mass). All the compounds were evaluat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a66db7432cab8cc97adbe465218591ab
https://pubmed.ncbi.nlm.nih.gov/27522460
https://pubmed.ncbi.nlm.nih.gov/27522460
Autor:
Shreekant Deshpande, Vadithe Lakshma Nayak, Anila Dwivedi, Vishal Chandra, Yenamandra S. Prabhakar, Devi Prasad Sahu, Shailesh Kumar, Shakti Kitchlu, Rituraj Konwar
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:6832-6840
A novel class of 2,3,4-triarylbenzopyrans has been synthesized and were evaluated for their selective estrogen receptor modulation activity and as a therapeutic agent for breast cancer. Among the compounds synthesized, compounds 11a and 12c exhibited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6a0bc8a567ff771a4c9171efc15bdd
https://doi.org/10.1016/j.bmc.2009.08.034
https://doi.org/10.1016/j.bmc.2009.08.034