Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Vadim Y Bolshakov"'
Autor:
Elif Engin, Kiersten S Smith, Yudong Gao, David Nagy, Rachel A Foster, Evgeny Tsvetkov, Ruth Keist, Florence Crestani, Jean-Marc Fritschy, Vadim Y Bolshakov, Mihaly Hajos, Scott A Heldt, Uwe Rudolph
Publikováno v:
eLife, Vol 5 (2016)
Recent findings indicate a high level of specialization at the level of microcircuits and cell populations within brain structures with regards to the control of fear and anxiety. The hippocampus, however, has been treated as a unitary structure in a
Externí odkaz:
https://doaj.org/article/36ba1eb9afb84233919d8ad50543f264
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The natural alignment of animals into social dominance hierarchies produces adaptive, and potentially maladaptive, changes in the brain that influence health and behavior. Aggressive and submissive behaviors assumed by animals through domina
Externí odkaz:
https://doaj.org/article/0245adb2834e4742b03a941185ff8ad1
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32483 (2012)
Kainate receptor (KAR) subunits are believed to be involved in abnormal GABAergic neurotransmission in the hippocampus (HIPP) in schizophrenia (SZ) and bipolar disorder. Postmortem studies have shown changes in the expression of the GluR5/6 subunits
Externí odkaz:
https://doaj.org/article/3453330dd5934f2bb35aa8b38180090e
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-12 (2023)
Abstract Mutations in the Presenilin genes (PSEN1 and PSEN2) are the major cause of familial Alzheimer’s disease (AD), highlighting the importance of Presenilin (PS) in AD pathogenesis. Previous studies of PS function in the hippocampus demonstrate
Externí odkaz:
https://doaj.org/article/1ed3f9ae389046659f943b531870fe49
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-11 (2021)
Abstract Mutations in the Presenilin genes are the major genetic cause of Alzheimer's disease (AD). Presenilin (PS) is highly expressed in the hippocampus, which is particularly vulnerable in AD. Previous studies of PS function in the hippocampus, ho
Externí odkaz:
https://doaj.org/article/79d0d79c0f2146daaf3ce090d7ed30a0
Publikováno v:
bioRxiv
The natural alignment of animals into social dominance hierarchies produces adaptive, and potentially maladaptive, changes in the brain that influence health and behavior. Aggressive and submissive behaviors assumed by animals through dominance inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d8ac0ba39cea2a542205034ac7ada6
https://europepmc.org/articles/PMC10187259/
https://europepmc.org/articles/PMC10187259/
Autor:
Rachel A Ross, Angela Kim, Priyanka Das, Yan Li, Yong Kee Choi, Andy T Thompson, Ella Douglas, Siva Subramanian, Kat Ramos, Kathryn Callahan, Vadim Y Bolshakov, Kerry J Ressler
BackgroundMelanocortin 4 receptor (MC4R) activity in the hypothalamus is crucial for regulation of metabolism and food intake. The peptide ligands for the MC4R are associated with feeding, energy expenditure, and also with complex behaviors that orch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a0c8aa3ede3ed7c5b573e8ccf7a5503
https://doi.org/10.1101/2022.06.01.494383
https://doi.org/10.1101/2022.06.01.494383
Autor:
Jeha Jeon, Bruce M. Cohen, Maria Jose Luna, Vadim Y. Bolshakov, Jeffrey Schweitzer, Hyemyung Seo, Kwang Soo Kim, Jin Hyuk Jung, Jisun Kim, Jeffrey H. Kordower, Claudia Lopes, Melissa Feitosa, Pierre Leblanc, Kyungjoon Park, Dabin Hwang, Young Joo Cha, Martin H. Teicher, Sek Won Kong, In-Hee Lee, Sanghyeok Ko, Bob S. Carter, Bin Song, Nayeon Lee
Publikováno v:
J Clin Invest
Parkinson's disease (PD) is a neurodegenerative disorder associated with loss of striatal dopamine, secondary to degeneration of midbrain dopamine (mDA) neurons in the substantia nigra, rendering cell transplantation a promising therapeutic strategy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc0ab0bd5d8f97f6fabb2546905482c
https://doi.org/10.1172/jci130767
https://doi.org/10.1172/jci130767
Autor:
Kyungjoon Park, Leonard M. Eisenberg, Fatima Arif, Alexander A. Moghadam, Vadim Y. Bolshakov, Clare Faux, John Parnevelas, Zhicheng Shao, Youxin Guan, Joshua J. Park, Haneul Noh, Sangmi Chung, Bill Andrews, Peiyan Ni, Cameron P Beaudreault, John N. Hutchinson, Patric K. Stanton, Elizabeth Berry, James M. Park, Chiderah P Abani, Joy S. Park, Qian Zhu
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss, Pp 414-430 (2019)
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss, Pp 414-430 (2019)
During development, cortical interneurons (cINs) are generated from the ventral telencephalon, robustly migrate to the dorsal telencephalon, make local synaptic connections, and critically regulate brain circuitry by inhibiting other neurons. Thus, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2eb0cf8b08e136bc42f73f91a82368
https://doi.org/10.1016/j.omtm.2019.04.002
https://doi.org/10.1016/j.omtm.2019.04.002
Publikováno v:
Translational Psychiatry, Vol 9, Iss 1, Pp 1-15 (2019)
Translational Psychiatry
Translational Psychiatry
Schizophrenia is a severe and highly heritable disorder. Dystrobrevin-binding protein 1 (DTNBP1), also known as dysbindin-1, has been implicated in the pathophysiology of schizophrenia. Specifically, dysbindin-1 mRNA and protein expression are decrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38895e6ffdc012752b8d9c8c16bb3f1a
http://link.springer.com/article/10.1038/s41398-019-0465-y
http://link.springer.com/article/10.1038/s41398-019-0465-y