Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Vadim V. Tarasov"'
Autor:
Eugenia D. Namiot, Diana Smirnovová, Aleksandr V. Sokolov, Vladimir N. Chubarev, Vadim V. Tarasov, Helgi B. Schiöth
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Major depressive disorder (MDD), commonly known as depression, affects over 300 million people worldwide as of 2018 and presents a wide range of clinical symptoms. The international clinical trials registry platform (ICTRP) introduced by WHO
Externí odkaz:
https://doaj.org/article/b8df8f8d7cd54867b9542d7c81a07943
Autor:
Eugenia D. Namiot, Diana Smirnovová, Aleksandr V. Sokolov, Vladimir N. Chubarev, Vadim V. Tarasov, Helgi B. Schiöth
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Clinical trials are the gold standard for testing new therapies. Databases like ClinicalTrials.gov provide access to trial information, mainly covering the US and Europe. In 2006, WHO introduced the global ICTRP, aggregating data from C
Externí odkaz:
https://doaj.org/article/ac2e9c102ff742b58fa25e0186c1c5c8
Autor:
Timofey O. Klyucherev, Pawel Olszewski, Alena A. Shalimova, Vladimir N. Chubarev, Vadim V. Tarasov, Misty M. Attwood, Stina Syvänen, Helgi B. Schiöth
Publikováno v:
Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-24 (2022)
Abstract Alzheimer's disease (AD) is a complex, heterogeneous, progressive disease and is the most common type of neurodegenerative dementia. The prevalence of AD is expected to increase as the population ages, placing an additional burden on nationa
Externí odkaz:
https://doaj.org/article/f56a63ad026244c5a41ddc10feb525cc
Autor:
Andrey D. Bondarev, Misty M. Attwood, Jörgen Jonsson, Vladimir N. Chubarev, Vadim V. Tarasov, Wen Liu, Helgi B. Schiöth
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The phosphodiesterase (PDE) enzymes, key regulator of the cyclic nucleotide signal transduction system, are long-established as attractive therapeutic targets. During investigation of trends within clinical trials, we have identified a particularly h
Externí odkaz:
https://doaj.org/article/a72af28bc4344e818bb63535d3d11b6c
Autor:
Victoria A. Nazarova, Aleksandr V. Sokolov, Vladimir N. Chubarev, Vadim V. Tarasov, Helgi B. Schiöth
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders having a high influence on social interactions. The number of approved treatments and clinical trials for ADHD have increased markedly during the r
Externí odkaz:
https://doaj.org/article/a83d1740cffa466d85ec8e56d3c17a5a
Autor:
Farzin Zobdeh, Ivan I. Eremenko, Mikail A. Akan, Vadim V. Tarasov, Vladimir N. Chubarev, Helgi B. Schiöth, Jessica Mwinyi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9127 (2023)
Migraine is a complex neurological disorder and a major cause of disability. A wide range of different drug classes such as triptans, antidepressants, anticonvulsants, analgesics, and beta-blockers are used in acute and preventive migraine therapy. D
Externí odkaz:
https://doaj.org/article/1c0b84a992d74fc7bf27822f3ef3637b
Autor:
Oreste Affatato, Thiago C. Moulin, Claudia Pisanu, Victoria S. Babasieva, Marco Russo, Elif I. Aydinlar, Paola Torelli, Vladimir N. Chubarev, Vadim V. Tarasov, Helgi B. Schiöth, Jessica Mwinyi
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-11 (2021)
Abstract Background Migraine and depression are highly prevalent and partly overlapping disorders that cause strong limitations in daily life. Patients tend to respond poorly to the therapies available for these diseases. OnabotulinumtoxinA has been
Externí odkaz:
https://doaj.org/article/03032ccf96e04212a8bb09a1da14db3c
Autor:
Eugenia D. Namiot, Aleksandr V. Sokolov, Vladimir N. Chubarev, Vadim V. Tarasov, Helgi B. Schiöth
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 787 (2023)
Nanoparticles are heterologous small composites that are usually between 1 and 100 nanometers in size. They are applied in many areas of medicine with one of them being drug delivery. Nanoparticles have a number of advantages as drug carriers which i
Externí odkaz:
https://doaj.org/article/ed5e27d863dd479b9b3c6bd747a5d1d7
Autor:
Irina I. Belyaeva, Anna G. Subbotina, Ivan I. Eremenko, Vadim V. Tarasov, Vladimir N. Chubarev, Helgi B. Schiöth, Jessica Mwinyi
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Primary headache disorders, such as migraine, tension-type headache (TTH), and cluster headache, belong to the most common neurological disorders affecting a high percentage of people worldwide. Headache induces a high burden for the affected individ
Externí odkaz:
https://doaj.org/article/724a911e158747bc9fbfc5092844b519
Autor:
Eugenia D. Namiot, Jenni Viivi Linnea Niemi, Vladimir N. Chubarev, Vadim V. Tarasov, Helgi B. Schiöth
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11453 (2022)
Neurological diseases can significantly reduce the quality and duration of life. Stem cells provide a promising solution, not only due to their regenerative features but also for a variety of other functions, including reducing inflammation and promo
Externí odkaz:
https://doaj.org/article/1b1b5559412d4942aba36d8dc711b0ee