Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Vadim Sagach"'
Diazoxide affects mitochondrial bioenergetics by the opening of mKATP channel on submicromolar scale
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background Cytoprotection afforded by mitochondrial ATP-sensitive K+-channel (mKATP-channel) opener diazoxide (DZ) largely depends on the activation of potassium cycle with eventual modulation of mitochondrial functions and ROS production. H
Externí odkaz:
https://doaj.org/article/01479c49d4eb4c4d8114b264c1dd9b28
Autor:
Olga Akopova, Anatoly Kotsiuruba, Yulia Korkach, Liudmila Kolchinskaya, Valentina Nosar, Bronislav Gavenauskas, Zoya Serebrovska, Iryna Mankovska, Vadim Sagach
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 1, Pp 193-204 (2016)
Background/Aims: NO and reactive nitrogen species (RNS) are thought to be physiologically important effectors of mitochondrial calcium transport, but this issue was not studied in a living organism. According to literature, the modulation of Ca2+ upt
Externí odkaz:
https://doaj.org/article/9b7eb3db901e4e628053c7bbf497eb0f
Autor:
Natalya, Dorofeyeva, Konstantin, Drachuk, Rajasekaran, Rajkumar, Omkar, Sabnis, Vadim, Sagach
Publikováno v:
European journal of clinical investigationREFERENCES. 51(1)
Diabetes dramatically increases the risk of cardiovascular complications and mortality. Hydrogen sulphide plays an important role in reducing oxidative stress. Several studies demonstrated that hydrogen sulphide protects islet beta cells from oxidant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a483cb4a56ad200f5ab4c960c978ea4
https://pubmed.ncbi.nlm.nih.gov/35699335
https://pubmed.ncbi.nlm.nih.gov/35699335
Autor:
Alexander I, Bondarenko, Konstantin, Drachuk, Olga, Panasiuk, Vadim, Sagach, Andras T, Deak, Roland, Malli, Wolfgang F, Graier
Publikováno v:
British Journal of Pharmacology
Background and Purpose N-arachidonoyl glycine (NAGly) is a lipoamino acid with vasorelaxant properties. We aimed to explore the mechanisms of NAGly's action on unstimulated and agonist-stimulated endothelial cells. Experimental Approach The effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8df20f3fa3e664b0ba07e8f36d40fb35
https://pubmed.ncbi.nlm.nih.gov/23517055
https://pubmed.ncbi.nlm.nih.gov/23517055
Publikováno v:
Experimental and clinical cardiology. 11(2)
Endothelial function is impaired in atherosclerosis, hypertension, diabetes and aging, and this may be associated with an attenuated ability of endothelial cells to generate nitric oxide (NO).To evaluate possible alterations in endothelium-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a323c5bb20f7c12f8a072d240827dd0b
https://pubmed.ncbi.nlm.nih.gov/18651045
https://pubmed.ncbi.nlm.nih.gov/18651045