Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Vadim S Ten"'
Autor:
Hylde Zirpoli, Maria Eugenia Bernis, Hemmen Sabir, Denny Joseph Manual Kollareth, James A. Hamilton, Nasi Huang, Jesse Ng, Sergey A. Sosunov, Ben Gaebler, Vadim S. Ten, Richard J. Deckelbaum
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116749- (2024)
Hypoxic-ischemic encephalopathy (HIE), resulting from a lack of blood flow and oxygen before or during newborn delivery, is a leading cause of cerebral palsy and neurological disability in children. Therapeutic hypothermia (TH), the current standard
Externí odkaz:
https://doaj.org/article/09898beb26164f4ab55eb2a4d98f52a4
Publikováno v:
Frontiers in Neurology, Vol 11 (2021)
Therapeutic hypothermia (HT) is a currently accepted treatment for neonatal asphyxia and is a promising strategy in adult stroke therapy. We previously reported that acute administration of docosahexaenoic acid (DHA) triglyceride emulsion (tri-DHA) p
Externí odkaz:
https://doaj.org/article/03664fea1d354677806e16f8d2ffc468
Autor:
Vadim S. Ten, Anna A. Stepanova, Veniamin Ratner, Maria Neginskaya, Zoya Niatsetskaya, Sergey Sosunov, Anatoly Starkov
Publikováno v:
Cells, Vol 10, Iss 3, p 569 (2021)
This review discusses the potential mechanistic role of abnormally elevated mitochondrial proton leak and mitochondrial bioenergetic dysfunction in the pathogenesis of neonatal brain and lung injuries associated with premature birth. Providing suppor
Externí odkaz:
https://doaj.org/article/09e69b44062041269d375e0a97da9328
Autor:
Courtney Juliano, Zoya V. Niatsetskaya, Alexander Galkin, Veniamin Ratner, Anna A. Stepanova, Sergey A. Sosunov, Vadim S. Ten
Publikováno v:
Pediatric Research. 91:1383-1390
BACKGROUND In the developing brain, the death of immature oligodendrocytes (OLs) has been proposed to explain a developmental window for vulnerability to white matter injury (WMI). However, in neonatal mice, chronic sublethal intermittent hypoxia (IH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab2f15bb0ae63f9abbe2be9d9f496384
https://doi.org/10.1038/s41390-021-01555-x
https://doi.org/10.1038/s41390-021-01555-x
Autor:
Korapat Mayurasakorn, Zoya V Niatsetskaya, Sergey A Sosunov, Jill J Williams, Hylde Zirpoli, Iliyan Vlasakov, Richard J Deckelbaum, Vadim S Ten
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160870 (2016)
Treatment with triglyceride emulsions of docosahexaenoic acid (tri-DHA) protected neonatal mice against hypoxia-ischemia (HI) brain injury. The mechanism of this neuroprotection remains unclear. We hypothesized that administration of tri-DHA enriches
Externí odkaz:
https://doaj.org/article/25908a8bcdaf4ecc90ae9ce63fff873f
Autor:
Hylde Zirpoli, Denny Joseph Kollareth Manual, Sergey A Sosunov, Sundas Rashid, Jesse Ng, Nasi Huang, Jaroslav Lralovec, Korapat Mayurasakorn, James A Hamilton, Vadim S Ten, Richard J Deckelbaum
Publikováno v:
Stroke. 53
Introduction: Omega-3 (n-3) fatty acids (FAs), specifically docohexaenoic acid (DHA) and eicosapentaenoic acid (EPA), act as bioactive unsaturated lipids with pleiotropic effects, affording neuroprotection in ischemic brain injury. Hypothesis: We rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8feba75231e15b083d08e1007845e02d
https://doi.org/10.1161/str.53.suppl_1.tp250
https://doi.org/10.1161/str.53.suppl_1.tp250
Autor:
Sergey A Sosunov, Xavier Ameer, Zoya V Niatsetskaya, Irina Utkina-Sosunova, Veniamin I Ratner, Vadim S Ten
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120456 (2015)
This study demonstrates that in mice subjected to hypoxia-ischemia (HI) brain injury isoflurane anesthesia initiated upon reperfusion limits a release of mitochondrial oxidative radicals by inhibiting a recovery of complex-I dependent mitochondrial r
Externí odkaz:
https://doaj.org/article/432e7a840dae49aea3ffffb6dae864ae
Autor:
Helu Liu, Wellington V. Cardoso, Anna Stepanova, Wei Wang, Vadim S. Ten, Jining Lu, Jessica E. Shui, Jun Qian, Grace V. Liao, Xingbin Ai
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
The impact of prematurity on human development and neonatal diseases, such as bronchopulmonary dysplasia, has been widely reported. However, little is known about the effects of prematurity on the programs of stem cell self-renewal and differentiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8cf2d40b01df1cc49ed5333ed7b7848
http://europepmc.org/articles/PMC8144386
http://europepmc.org/articles/PMC8144386
Autor:
Sergey A, Sosunov, Zoya V, Niatsetskaya, Anna A, Stepanova, Alexander S, Galkin, Courtney E, Juliano, Veniamin I, Ratner, Vadim S, Ten
Publikováno v:
Pediatric research. 91(6)
In the developing brain, the death of immature oligodendrocytes (OLs) has been proposed to explain a developmental window for vulnerability to white matter injury (WMI). However, in neonatal mice, chronic sublethal intermittent hypoxia (IH) recapitul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::643e5139f6e1c760c3880ca4245e57f3
https://pubmed.ncbi.nlm.nih.gov/33947998
https://pubmed.ncbi.nlm.nih.gov/33947998
Autor:
Irina V Utkina-Sosunova, Zoya V Niatsetskaya, Sergey A Sosunov, Veniamin I Ratner, Dzmitry Matsiukevich, Vadim S Ten
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62448 (2013)
Nelfinavir (NLF), an antiretroviral agent, preserves mitochondrial membranes integrity and protects mature brain against ischemic injury in rodents. Our study demonstrates that in neonatal mice NLF significantly limits mitochondrial calcium influx, t
Externí odkaz:
https://doaj.org/article/28ca643e5f904cae9f3ba282b11cc326