Výsledky vyhledávání - "Vadim Pivniouk"

The OM-85 bacterial lysate: A new tool against SARS-CoV-2?

Publikováno v: Multidisciplinary Respiratory Medicine. 18

The emergence of SARS-CoV-2, a novel coronavirus, caused the global Coronavirus disease of 2019 (COVID-19) pandemic. Because SARS-CoV-2 mutates rapidly, vaccines that induce immune responses against viral components critical for target cell infection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b3e8fab507292d6bad3d8f0ca92a0a1e
https://doi.org/10.4081/mrm.2023.906

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Airway administration of OM-85, a bacterial lysate, blocks experimental asthma by targeting dendritic cells and the epithelium/IL-33/ILC2 axis

Autor: Sydney R. VanLinden, Dayna Anderson, Seongmin Hahn, Justyna Gozdz, Fernando D. Martinez, Sean P. Malone, Avery DeVries, Peace C. Ezeh, Vadim Pivniouk, Oksana Pivniouk, Donata Vercelli, Joao A. Gimenes-Junior, Ashley Michael, Christian Pasquali, Amir Abidov

Publikováno v: J Allergy Clin Immunol

Background Microbial interventions against allergic asthma have robust epidemiologic underpinnings and the potential to recalibrate disease-inducing immune responses. Oral administration of OM-85, a standardized lysate of human airways bacteria, is w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44894e1dc585afceb0871e97f563fe4
https://europepmc.org/articles/PMC8901455/

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Intra-Nasal Administration of the OM-85 Bacterial Lysate Strongly Protects from Experimental Asthma by Targeting Multiple Innate and Adaptive Immune Processes

Autor: A.N. Michael, A. Abidov, Vadim Pivniouk, Oksana Pivniouk, J.A. Gimenes, Avery DeVries, Peace C. Ezeh, Justyna Gozdz, Donata Vercelli, C. Pasquali

Publikováno v: A21. AIRWAY IMMUNOLOGY.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d033e0106bdd0c2460f56485d9660f09
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1058

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The role of innate immunity in asthma development and protection: Lessons from the environment

Autor: Donata Vercelli, Joao Antonio Gimenes Junior, Vadim Pivniouk, Linnea K. Honeker

Publikováno v: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyREFERENCES. 50(3)

Asthma, a complex, chronic disease characterized by airway inflammation, hyperresponsiveness and remodelling, affects over 300 million people worldwide. While the disease is typically associated with exaggerated allergen-induced type 2 immune respons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7370d4315031fd34987433d38f55aed2
https://pubmed.ncbi.nlm.nih.gov/31581343

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Gut Microbiota from Amish but Not Hutterite Children Protect Germ-Free Mice from Experimental Asthma

Autor: Ashokkumar M. Sharma, Vadim Pivniouk, B. Theriault, Jack A. Gilbert, Catherine Igartua, J.A. Gimenes, E. von Mutius, K. Patil, Justyna Gozdz, Mark Holbreich, Linnea K. Honeker, Donata Vercelli, Michelle M. Stein, C. Ober, A. Horner

Publikováno v: D92. THE MICROBIOME AND LUNG DISEASE.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::69f2b578d6e816b98bd3d240c06af263
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7022

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Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children

Publikováno v: New England Journal of Medicine. 375:411-421

BackgroundThe Amish and Hutterites are U.S. agricultural populations whose lifestyles are remarkably similar in many respects but whose farming practices, in particular, are distinct; the former follow traditional farming practices whereas the latter

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https://doi.org/10.1056/nejmoa1508749

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Impaired signaling via the high-affinity IgE receptor in Wiskott-Aldrich syndrome protein-deficient mast cells

Autor: Harri Alenius, Vadim Pivniouk, Raif S. Geha, Scott B. Snapper, Frederick W. Alt, Alexander Kettner, Hervé Falet, Dhafer Laouini, John H. Hartwig

Publikováno v: International Immunology. 15:1431-1440

Wiskott-Aldrich syndrome protein (WASP) is the product of the gene deficient in boys with X-linked Wiskott-Aldrich syndrome. We assessed the role of WASP in signaling through the high-affinity IgE receptor (FcepsilonRI) using WASP-deficient mice. IgE

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https://doi.org/10.1093/intimm/dxg148

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The Binding Site for TRAF2 and TRAF3 but Not for TRAF6 Is Essential for CD40-Mediated Immunoglobulin Class Switching

Autor: Scott R. Brodeur, Haifa H. Jabara, Atul K. Bhan, Emanuela Castigli, Vadim Pivniouk, Fatma Dedeoglu, Raif S. Geha, Emiko Mizoguchi, Dhafer Laouini, Erdyni N. Tsitsikov

Publikováno v: Immunity. 17(3):265-276

To define the role of TRAF proteins in CD40-dependent isotype switching in B cells, we introduced wild-type (WT) and mutant CD40 transgenes that lacked the binding motifs for TRAF6 (CD40deltaTRAF6), TRAF2 and TRAF3 (CD40deltaTRAF2/3), or both (CD40de

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The role of SLP-76 and LAT in lymphocyte development

Autor: Raif S. Geha, Vadim Pivniouk

Publikováno v: Current Opinion in Immunology. 12:173-178

SLP-76 and LAT are two recently identified adapter proteins that are involved in the signal transduction cascade initiated by engagement of the TCR. The role of these two molecules in thymocyte development has become clearer following studies of gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce405a41dc70829a50ac1263406b4c47
https://doi.org/10.1016/s0952-7915(99)00068-0

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