Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vadim L. Mett"'
Autor:
Craig M. Brackett, Catherine Burkhart, Ilia Toshkov, Andrei L. Osterman, Ivan A. Bespalov, Andrei Purmal, Vadim L. Mett, Andrei V. Gudkov, Lyudmila G. Burdelya, Yakov N. Kogan, Anatoli S. Gleiberman, Ekaterina L. Andrianova, Ivan Molodtsov, Oleg V. Kurnasov
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology
Communications Biology
The Toll-like receptor 5 (TLR5) agonist entolimod, a derivative of Salmonella flagellin, has therapeutic potential for several indications including radioprotection and cancer immunotherapy. However, in Phase 1 human studies, entolimod induced a rapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdef2dd5c9aac4df928eea9fe09e4c96
https://doaj.org/article/bcafc6dab7b74c02bc2aec45e9ac993a
https://doaj.org/article/bcafc6dab7b74c02bc2aec45e9ac993a
Autor:
Vasily I Kazey, Natalia V Eremina, Sergey V Mishugin, Roman V Leonenkov, Vadim L. Mett, Dmitry Pushkar, Andrei V. Gudkov
Publikováno v:
Oncotarget
Toll-like receptor 5 (TLR5) controls endogenous immune responses to pathogens and is a promising target for pharmacological stimulation of anti-tumor immunity. Mobilan is an innovative gene therapy agent consisting of a non-replicating bicistronic ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b97b7a612b83cc01d6bc1b645c6fec
https://pubmed.ncbi.nlm.nih.gov/32292576
https://pubmed.ncbi.nlm.nih.gov/32292576
Autor:
Elena A. Komarova, Ellen Karasik, Bryan Gillard, Anatoly S. Gleiberman, M Bapardekar-Nair, Oleg V. Kurnasov, Semra Aygun-Sunar, Christopher Johnson, Vadim L. Mett, Andrei L. Osterman, Andrei V. Gudkov, Carl Morrison, Ivan A. Bespalov, Ilya Toshkov, Craig M. Brackett, Kellee F. Greene, Barbara A. Foster, Patricia Stanhope-Baker, Michael T. Moser
Publikováno v:
Oncogene
Toll-like receptor 5 (TLR5) is considered an attractive target for anticancer immunotherapy. TLR5 agonists, bacterial flagellin and engineered flagellin derivatives, have been shown to have potent antitumor and metastasis-suppressive effects in multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f554da51ebc5120ef78dfc73b88db3e8
https://doi.org/10.1038/onc.2017.346
https://doi.org/10.1038/onc.2017.346
Autor:
Michelle Wrobel, Semra Aygun-Sunar, Andrei L. Osterman, Christelle M. Roux, Anatoli S. Gleiberman, David Frescas, Marina P. Antoch, Evguenia Strom, Peter Krasnov, Olga B. Chernova, Vadim L. Mett, Andrei V. Gudkov, Oleg V. Kurnasov, Lauren P. Virtuoso
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(9)
Studying the phenomenon of cellular senescence has been hindered by the lack of senescence-specific markers. As such, detection of proteins informally associated with senescence accompanies the use of senescence-associated β-galactosidase as a colle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7fb2e57ba54c957b546ae47ff9948c
https://pubmed.ncbi.nlm.nih.gov/28193858
https://pubmed.ncbi.nlm.nih.gov/28193858
Autor:
Lyudmila G. Burdelya, Ilia Toshkov, Alan D. Hutson, Anurag K. Singh, Anatoli S. Gleiberman, Vadim L. Mett, Andrei V. Gudkov
Publikováno v:
Radiation Research. 187:570
Radiation treatment of head and neck cancer frequently causes severe collateral damage to normal tissues including mouth mucosa, salivary glands and skin. This toxicity limits the radiation dose that can be delivered and affects the patient’s quali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295f1350b6e39af6fdb02cc92d465f5d
https://doi.org/10.1667/rr14514.1
https://doi.org/10.1667/rr14514.1
Publikováno v:
Protein & Peptide Letters. 7:175-182
Abstract: A single chain antibody mimic (MScFvlOE7) was constructed, using a phage display recombinant antibody system, from RNA isolated from the splenocytes of mice immunised with monoclonal antibody MAblOC12 which recognises the furan ring of DOTH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cec87802a0234e3d87ab8e83e270110
https://doi.org/10.2174/092986650703221206122640
https://doi.org/10.2174/092986650703221206122640
Publikováno v:
Protein & Peptide Letters. 3:95-100
Abstract: Using hybridoma 7Fl which secretes antibodies specific tor aspartate aminotransferase-P2 (AAT-P2) as the source of RNA, a single chain antibody has been constructed using a phage display recombinant antibody system. The molecule produced in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae934779c3b8d1cb14eea8af06ce897f
https://doi.org/10.2174/092986650203220614105328
https://doi.org/10.2174/092986650203220614105328
Autor:
Ilya M. Chumakov, Vadim L. Mett, Lev L. Kisselev, Eugene R. Zabarovsky, Vladimir S. Prassolov
Publikováno v:
Gene. 17(1)
A recombinant plasmid, pI26, has been constructed by cloning into pBR322 a transforming gene of murine sarcoma virus (a Moloney strain, clone 124, MSV) synthesized by detergent-treated virions. From this plasmid a XbaI-HindIII fragment has been isola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac04a7f4e253f943f0cebfa4903f964
https://pubmed.ncbi.nlm.nih.gov/6281133
https://pubmed.ncbi.nlm.nih.gov/6281133