Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Vadim Kostousov"'
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
For decades, unfractionated heparin (hereafter, heparin) has been the primary anticoagulant used for extracorporeal membrane oxygenation (ECMO) support. More recently, however, bivalirudin, a direct thrombin inhibitor, has emerged as an alternative.
Externí odkaz:
https://doaj.org/article/832adf2705bc4173a969d6c88fcb11bb
Autor:
Galit H. Frydman, DVM, ScD, Barry M. Berger, MD, FCAP, Vadim Kostousov, MD, Karen Bruzdovski, BS, Dimitrios P. Papageorgiou, PhD, Amir Navaei, MD, Shiu-Ki Rocky Hui, MD, Jun Teruya, MD, DSc
Publikováno v:
Critical Care Explorations, Vol 4, Iss 10, p e0776 (2022)
OBJECTIVES:. Bivalirudin, an IV direct thrombin inhibitor, and unfractionated heparin (UFH) are frequently used anticoagulants in the pediatric critical care setting. An accurate, specific, point-of-care test to quantify and detect anticoagulation re
Externí odkaz:
https://doaj.org/article/1cf518411f5845ae8d4a108f8c918588
Autor:
Robert Bartlett, Deepa J. Arachichilage, Meera Chitlur, Shiu-Ki Rocky Hui, Cindy Neunert, Andrew Doyle, Andrew Retter, Beverley J Hunt, Hoong Sern Lim, Arun Saini, Thomas Renné, Vadim Kostousov, Jun Teruya
Publikováno v:
Seminars in Thrombosis and Hemostasis.
Extracorporeal membrane oxygenation (ECMO) was first started for humans in early 1970s by Robert Bartlett. Since its inception, there have been numerous challenges with extracorporeal circulation, such as coagulation and platelet activation, followed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfe43470a94747c95b163502f9ec8bb3
https://doi.org/10.1055/s-0043-1761488
https://doi.org/10.1055/s-0043-1761488
Autor:
Shiu-Ki Rocky Hui, Vadim Kostousov, Steven L. Clark, Amir A. Shamshirsaz, Hadi Erfani, Jun Teruya, Lisa Hensch, Karen Bruzdoski, Karin A. Fox
Publikováno v:
International Journal of Laboratory Hematology. 43:1216-1224
Introduction Rotational thromboelastometry (ROTEM) rapidly identifies deficits underlying coagulopathy during massive hemorrhage. Prompt coagulopathy correction is balanced with the risk of blood product overutilization, making the ability to quickly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::877f2215592fd54415d1ff35a9e4e249
https://doi.org/10.1111/ijlh.13472
https://doi.org/10.1111/ijlh.13472
Autor:
Shiu Ki Rocky Hui, Zhe Amy Fang, Karen Bruzdoski, Jun Teruya, Vadim Kostousov, Erin A. Gottlieb, David F. Vener
Publikováno v:
Transfusion. 60:2841-2848
Background Neonates have lower levels of antithrombin (AT) due to immature liver synthetic function. AT deficiency may lead to inadequate anticoagulation with heparin during cardiac surgery resulting in consumption of coagulation factors and increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b2570d20829901007a0c9703e5ea1e
https://doi.org/10.1111/trf.16082
https://doi.org/10.1111/trf.16082
Autor:
Karen Bruzdoski, Sridevi Devaraj, Jun Teruya, Lisa Hensch, Shiu-Ki Rocky Hui, Vadim Kostousov
Publikováno v:
International Journal of Laboratory Hematology. 43:139-142
Introduction Activated partial thromboplastin time (aPTT) and antifactor Xa (anti-Xa) activity are used to monitor unfractionated heparin therapy in children on extracorporeal membrane oxygenation (ECMO). Elevated C-reactive protein (CRP) can prolong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65baf7e93b50991d8fba9af8a55fee4
https://doi.org/10.1111/ijlh.13314
https://doi.org/10.1111/ijlh.13314
Publikováno v:
Thrombosis Research. 186:54-57
Introduction Bivalirudin is an alternative to heparin anticoagulation in infants and children in the setting of extracorporeal life support (ECLS). While activated partial thromboplastin time (aPTT) is widely accepted as the standard test to monitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0754bfc8cdf8693b7e4c05bb5716ec
https://doi.org/10.1016/j.thromres.2019.12.007
https://doi.org/10.1016/j.thromres.2019.12.007
Autor:
Nathan Wilken, Vadim Kostousov, Karen Bruzdoski, Sarah Elizabeth Sartain, Kristen Krum, Lisa Hensch, Jun Teruya, Shiu-Ki Rocky Hui
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f84efb3b2706d9dd2f7d9404af2db07e
https://doi.org/10.2139/ssrn.4272507
https://doi.org/10.2139/ssrn.4272507
Publikováno v:
International journal of laboratory hematologyREFERENCES. 44(3)
Unfractionated heparin is widely used as an anticoagulant for extracorporeal life support (ECLS) and usually monitored with activated partial thromboplastin time (aPTT). Due to its limitations in pediatric populations and interferences with monitorin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1972c32ea6349a96ce367cdce61308
https://pubmed.ncbi.nlm.nih.gov/34939341
https://pubmed.ncbi.nlm.nih.gov/34939341
Publikováno v:
Seminars in Thrombosis and Hemostasis. 44:020-029
Extracorporeal membrane oxygenation (ECMO) has been used for >40 years to support lung and heart failure; however, bleeding and thrombosis remain serious complications. The known etiologies of bleeding include heparin effect or overdose, coagulopathy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c4771ed4868213a02ab23ef096a06b
https://doi.org/10.1055/s-0037-1606179
https://doi.org/10.1055/s-0037-1606179