Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Vadim E Fraifeld"'
Autor:
Dmitri Toren, Hagai Yanai, Reem Abu Taha, Gabriela Bunu, Eugen Ursu, Rolf Ziesche, Robi Tacutu, Vadim E Fraifeld
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Tissue fibrosis is a major driver of pathology in aging and is involved in numerous age-related diseases. The lungs are particularly susceptible to fibrotic pathology which is currently difficult to treat. The mouse bleomycin-induced fibrosi
Externí odkaz:
https://doaj.org/article/6f385b81d7a846bd95a98ccaec205d2d
Autor:
Robi Tacutu, David E Shore, Arie Budovsky, João Pedro de Magalhães, Gary Ruvkun, Vadim E Fraifeld, Sean P Curran
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48282 (2012)
Intricate and interconnected pathways modulate longevity, but screens to identify the components of these pathways have not been saturating. Because biological processes are often executed by protein complexes and fine-tuned by regulatory factors, th
Externí odkaz:
https://doaj.org/article/235eff5c410c4ffc809e0b3280203fe9
Autor:
Roberto A. Avelar, Javier Gómez Ortega, Robi Tacutu, Eleanor J. Tyler, Dominic Bennett, Paolo Binetti, Arie Budovsky, Kasit Chatsirisupachai, Emily Johnson, Alex Murray, Samuel Shields, Daniela Tejada-Martinez, Daniel Thornton, Vadim E. Fraifeld, Cleo L. Bishop, João Pedro de Magalhães
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-22 (2020)
Abstract Background Cellular senescence, a permanent state of replicative arrest in otherwise proliferating cells, is a hallmark of aging and has been linked to aging-related diseases. Many genes play a role in cellular senescence, yet a comprehensiv
Externí odkaz:
https://doaj.org/article/7b84219b475d4993ae23863cf7f41947
Publikováno v:
Fibrosis. 1:1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ef2acdfaea0f60ef94c203b34341c79
https://doi.org/10.35534/fibrosis.2023.10002
https://doi.org/10.35534/fibrosis.2023.10002
Publikováno v:
Biogerontology. 23:425-430
The linear no-threshold (LNT) hypothesis is still the ruling concept which dictates the radiation protection health policy and regulations. However, more and more studies show that not only that low dose radiation pose no danger to our health, but al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::288dd3ed142f4a94cd2d156627431870
https://doi.org/10.1007/s10522-022-09971-0
https://doi.org/10.1007/s10522-022-09971-0
Autor:
Marco Chilosi, Fabrizio Vinante, Claudio Doglioni, Giovanni Pizzolo, Hagai Yanai, Marina Wolfson, Vadim E. Fraifeld, Claudia Parolini, Licia Montagna, Serena Pedron, Andrés J.M. Ferreri, Maria Elisabetta Zanolin, Maurilio Ponzoni, Alberto Zamò, Anna Caliò
Prognostic significance of the combined variable p16INK4a/p21CIP1/WAF1 in patients with cHL.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0acd9afd24ccc0ffeeab9720f1031226
https://doi.org/10.1158/1078-0432.22456154
https://doi.org/10.1158/1078-0432.22456154
Autor:
Marco Chilosi, Fabrizio Vinante, Claudio Doglioni, Giovanni Pizzolo, Hagai Yanai, Marina Wolfson, Vadim E. Fraifeld, Claudia Parolini, Licia Montagna, Serena Pedron, Andrés J.M. Ferreri, Maria Elisabetta Zanolin, Maurilio Ponzoni, Alberto Zamò, Anna Caliò
Table S1. Multivariate analysis for event occurrence in 132/147* patients. Table S2. Probability of EFS (95%CI) according sCD30 and p16INK4a/p21CIP1/WAF1 expression at diagnosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278bd7d7caefbb2d7afdb9b7a438cf47
https://doi.org/10.1158/1078-0432.22456148.v1
https://doi.org/10.1158/1078-0432.22456148.v1
Autor:
Marco Chilosi, Fabrizio Vinante, Claudio Doglioni, Giovanni Pizzolo, Hagai Yanai, Marina Wolfson, Vadim E. Fraifeld, Claudia Parolini, Licia Montagna, Serena Pedron, Andrés J.M. Ferreri, Maria Elisabetta Zanolin, Maurilio Ponzoni, Alberto Zamò, Anna Caliò
MARQ analysis for common gene expression signatures of Hodgkin's lymphoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7993ca6151ee60d1262cf26adf6fed
https://doi.org/10.1158/1078-0432.22456145.v1
https://doi.org/10.1158/1078-0432.22456145.v1
Autor:
Marco Chilosi, Fabrizio Vinante, Claudio Doglioni, Giovanni Pizzolo, Hagai Yanai, Marina Wolfson, Vadim E. Fraifeld, Claudia Parolini, Licia Montagna, Serena Pedron, Andrés J.M. Ferreri, Maria Elisabetta Zanolin, Maurilio Ponzoni, Alberto Zamò, Anna Caliò
Purpose: There is evidence that Hodgkin Reed-Sternberg (HRS) cells in classical Hodgkin lymphoma (cHL) could display some molecular and morphologic markers of cellular senescence (CS). We hypothesized that CS mechanisms may have potential prognostic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f53010d501c3e7ad5daf068e8f16dd5
https://doi.org/10.1158/1078-0432.c.6523220.v1
https://doi.org/10.1158/1078-0432.c.6523220.v1
Autor:
Anna Knyazer, Gabriela Bunu, Dmitri Toren, Teodora Bucaciuc Mracica, Yael Segev, Marina Wolfson, Khachik K. Muradian, Robi Tacutu, Vadim E. Fraifeld
Publikováno v:
Aging (Albany NY)
If somatic stem cells would be able to maintain their regenerative capacity over time, this might, to a great extent, resolve rejuvenation issues. Unfortunately, the pool of somatic stem cells is limited, and they undergo cell aging with a consequent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5263134f32db68b8cd9e8043d74b4db4
https://doi.org/10.18632/aging.203791
https://doi.org/10.18632/aging.203791