Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Vadim A. Bolshakov"'
Publikováno v:
Статистика и экономика, Vol 0, Iss 2, Pp 129-132 (2016)
The authors consider some features of use of the main criteria of decision efficiency in the stock management in terms of a risk based on the manufacturing situations such as criterion of an expectation value, criterion of a threshold level and crite
Externí odkaz:
https://doaj.org/article/cb4aad64eb794368b52aac70a0a62839
Publikováno v:
Статистика и экономика, Vol 0, Iss 6, Pp 155-158 (2016)
In the present paper is an extension of the paper «Some generalizations of the management system with the main stock» published in [1]. The analytical dependence of the random variable rate of working capital for the most common of the probability
Externí odkaz:
https://doaj.org/article/beef7c7b3d1549b9ba6a4a84b15ca538
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The natural alignment of animals into social dominance hierarchies produces adaptive, and potentially maladaptive, changes in the brain that influence health and behavior. Aggressive and submissive behaviors assumed by animals through domina
Externí odkaz:
https://doaj.org/article/0245adb2834e4742b03a941185ff8ad1
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-12 (2023)
Abstract Mutations in the Presenilin genes (PSEN1 and PSEN2) are the major cause of familial Alzheimer’s disease (AD), highlighting the importance of Presenilin (PS) in AD pathogenesis. Previous studies of PS function in the hippocampus demonstrate
Externí odkaz:
https://doaj.org/article/1ed3f9ae389046659f943b531870fe49
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-11 (2021)
Abstract Mutations in the Presenilin genes are the major genetic cause of Alzheimer's disease (AD). Presenilin (PS) is highly expressed in the hippocampus, which is particularly vulnerable in AD. Previous studies of PS function in the hippocampus, ho
Externí odkaz:
https://doaj.org/article/79d0d79c0f2146daaf3ce090d7ed30a0
Autor:
Peiyan Ni, Haneul Noh, Zhicheng Shao, Qian Zhu, Youxin Guan, Joshua J. Park, Fatima Arif, James M. Park, Chiderah Abani, Cameron Beaudreault, Joy S. Park, Elizabeth Berry, Alexander Moghadam, Patric Stanton, John N. Hutchinson, Bill Andrews, Clare Faux, John Parnevelas, Leonard M. Eisenberg, Kyungjoon Park, Vadim Y. Bolshakov, Sangmi Chung
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss , Pp 414-430 (2019)
During development, cortical interneurons (cINs) are generated from the ventral telencephalon, robustly migrate to the dorsal telencephalon, make local synaptic connections, and critically regulate brain circuitry by inhibiting other neurons. Thus, t
Externí odkaz:
https://doaj.org/article/66ad75cbb92c4f76b4426804c1f0cfa2
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-15 (2017)
Abstract Background Presenilins play a major role in the pathogenesis of Alzheimer’s disease, in which the hippocampus is particularly vulnerable. Previous studies of Presenilin function in the synapse, however, focused exclusively on the hippocamp
Externí odkaz:
https://doaj.org/article/95b5cc97636e465598c00f8c5c850297
Publikováno v:
bioRxiv
The natural alignment of animals into social dominance hierarchies produces adaptive, and potentially maladaptive, changes in the brain that influence health and behavior. Aggressive and submissive behaviors assumed by animals through dominance inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d8ac0ba39cea2a542205034ac7ada6
https://europepmc.org/articles/PMC10187259/
https://europepmc.org/articles/PMC10187259/
Autor:
Rachel A Ross, Angela Kim, Priyanka Das, Yan Li, Yong Kee Choi, Andy T Thompson, Ella Douglas, Siva Subramanian, Kat Ramos, Kathryn Callahan, Vadim Y Bolshakov, Kerry J Ressler
BackgroundMelanocortin 4 receptor (MC4R) activity in the hypothalamus is crucial for regulation of metabolism and food intake. The peptide ligands for the MC4R are associated with feeding, energy expenditure, and also with complex behaviors that orch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a0c8aa3ede3ed7c5b573e8ccf7a5503
https://doi.org/10.1101/2022.06.01.494383
https://doi.org/10.1101/2022.06.01.494383
Autor:
Jeha Jeon, Bruce M. Cohen, Maria Jose Luna, Vadim Y. Bolshakov, Jeffrey Schweitzer, Hyemyung Seo, Kwang Soo Kim, Jin Hyuk Jung, Jisun Kim, Jeffrey H. Kordower, Claudia Lopes, Melissa Feitosa, Pierre Leblanc, Kyungjoon Park, Dabin Hwang, Young Joo Cha, Martin H. Teicher, Sek Won Kong, In-Hee Lee, Sanghyeok Ko, Bob S. Carter, Bin Song, Nayeon Lee
Publikováno v:
J Clin Invest
Parkinson's disease (PD) is a neurodegenerative disorder associated with loss of striatal dopamine, secondary to degeneration of midbrain dopamine (mDA) neurons in the substantia nigra, rendering cell transplantation a promising therapeutic strategy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc0ab0bd5d8f97f6fabb2546905482c
https://doi.org/10.1172/jci130767
https://doi.org/10.1172/jci130767