Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vaclav Hejret"'
Autor:
Vaclav Hejret, Nandan Mysore Varadarajan, Eva Klimentova, Katarina Gresova, Ilektra-Chara Giassa, Stepanka Vanacova, Panagiotis Alexiou
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Argonaute proteins are instrumental in regulating RNA stability and translation. AGO2, the major mammalian Argonaute protein, is known to primarily associate with microRNAs, a family of small RNA ‘guide’ sequences, and identifies its tar
Externí odkaz:
https://doaj.org/article/f8b38a445ddc4ba58cfc3319cccb785e
Autor:
Veronika Mancikova, Michaela Pesova, Sarka Pavlova, Robert Helma, Kristyna Zavacka, Vaclav Hejret, Petr Taus, Jakub Hynst, Karla Plevova, Jitka Malcikova, Sarka Pospisilova
Publikováno v:
Molecular Oncology, Vol 17, Iss 1, Pp 82-97 (2023)
TP53 gene abnormalities represent the most important biomarker in chronic lymphocytic leukemia (CLL). Altered protein modifications could also influence p53 function, even in the wild‐type protein. We assessed the impact of p53 protein phosphorylat
Externí odkaz:
https://doaj.org/article/d23f7fd800de4b44a79aa2866eceb35e
Autor:
Veronika Mancikova, Michaela Pesova, Sarka Pavlova, Robert Helma, Kristyna Zavacka, Vaclav Hejret, Petr Taus, Jakub Hynst, Karla Plevova, Jitka Malcikova, Sarka Pospisilova
Publikováno v:
MOLECULAR ONCOLOGY
TP53 gene abnormalities represent the most important biomarker in chronic lymphocytic leukemia (CLL). Altered protein modifications could also influence p53 function, even in the wild-type protein. We assessed the impact of p53 protein phosphorylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94f83448458456a9ca3b6618bb055d3
https://doi.org/10.1002/1878-0261.13337
https://doi.org/10.1002/1878-0261.13337
Autor:
null Veronika Mancikova, null Michaela Pesova, null Sarka Pavlova, null Robert Helma, null Kristyna Zavacka, null Vaclav Hejret, null Petr Taus, null Jakub Hynst, null Karla Plevova, null Jitka Malcikova, null Sarka Pospisilova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c701c231e672495f249bb95db5df114
https://doi.org/10.1002/1878-0261.13337/v2/response1
https://doi.org/10.1002/1878-0261.13337/v2/response1
Autor:
Velina S Atanasova, Crhistian de Jesus Cardona, Vaclav Hejret, Andreas Tiefenbacher, Loan Tran, Carina Binder, Theresia Mair, Julijan Kabiljo, Janik Clement, Katharina Woeran, Barbara Neudert, Markus Hengstschläger, Markus Mitterhauser, Leonhard Müllauer, Boris Tichy, Michael Bergmann, Gabriele Schweikert, Markus Hartl, Helmut Dolznig, Gerda Egger
Patient-derived organoid (PDO) cancer models are generated from epithelial tumor cells. Although they reflect the molecular tumor characteristics, they lack the complexity of the tumor microenvironment, which is a key driver of tumorigenesis and ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7056150f57cf205623b4097a7bc3d202
https://doi.org/10.1101/2022.03.07.483214
https://doi.org/10.1101/2022.03.07.483214
Autor:
Stepanka Vanacova, Fabiana Martino, Francesca Cavalieri, Helena Durikova, Vladimír Horváth, Stefania Pagliari, André P. Gerber, Vaclav Hejret, Mary A. O’Connell, Ana Rubina Perestrelo, Waleed S. Albihlal, Frank Caruso, Nandan Mysore Varadarajan, Giancarlo Forte
Cardiac pathologies are characterized by intense remodeling of the extracellular matrix (ECM) that eventually leads to heart failure. Cardiomyocytes respond to the ensuing biomechanical stress by re-expressing fetal contractile proteins via transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e8b7b46008dd17e48737a458de92851
https://doi.org/10.1101/2021.08.27.457906
https://doi.org/10.1101/2021.08.27.457906
Autor:
Veronika Jedličková, Václav Hejret, Martin Demko, Pavel Jedlička, Marie Štefková, Hélène S. Robert
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Plant sexual reproduction is highly sensitive to elevated ambient temperatures, impacting seed development and production. We previously phenotyped this effect on three rapeseed cultivars (DH12075, Topas DH4079, and Westar). This
Externí odkaz:
https://doaj.org/article/152de98288d94656ada5b4d8b6077d75
Autor:
Velina S. Atanasova, Crhistian de Jesus Cardona, Václav Hejret, Andreas Tiefenbacher, Theresia Mair, Loan Tran, Janette Pfneissl, Kristina Draganić, Carina Binder, Julijan Kabiljo, Janik Clement, Katharina Woeran, Barbara Neudert, Sabrina Wohlhaupter, Astrid Haase, Sandra Domazet, Markus Hengstschläger, Markus Mitterhauser, Leonhard Müllauer, Boris Tichý, Michael Bergmann, Gabriele Schweikert, Markus Hartl, Helmut Dolznig, Gerda Egger
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 6, Pp 1391-1419 (2023)
Background & Aims: Patient-derived organoid cancer models are generated from epithelial tumor cells and reflect tumor characteristics. However, they lack the complexity of the tumor microenvironment, which is a key driver of tumorigenesis and therapy
Externí odkaz:
https://doaj.org/article/4731d5078fae4db69082355f0d4fbdc9