Analog and Mixed-Signal Hardware Description Language. [elektronicky zdroj]

Autor: Vachoux, A.

Externí odkaz: Kolekce e-knih KNAV (Registrovani uzivatele: plny text online 5 minut, dalsi pristup na vyzadani. Registered users: full text online 5 minutes, further access on requests.)(Registrovani uzivatele: plny text online 5 minut, dalsi pristup na vyzadani. Registered users: full text online 5 minutes, further access on requests.)

Model‐Based Quantification of Impact of Genetic Polymorphisms and Co‐Medications on Pharmacokinetics of Tamoxifen and Six Metabolites in Breast Cancer

Autor: Laurence Venat-Bouvet, Melanie White-Koning, William Jacot, Alicja Puszkiel, Jacques Robert, Etienne Chatelut, Hortense Laharie-Mineur, Thomas Filleron, Valérie Le Morvan, N. Dohollou, Marc Debled, Florence Dalenc, Chantal Bernard-Marty, Alexandre Evrard, Caroline Delmas, Fabienne Thomas, Henri Roché, Jean-Christophe Boyer, Cécile Arellano, Christelle Vachoux

Publikováno v: Clinical Pharmacology & Therapeutics. 109:1244-1255

Variations in clinical response to tamoxifen (TAM) may be related to polymorphic cytochromes P450 (CYPs) involved in forming its active metabolite endoxifen (ENDO). We developed a population pharmacokinetic (PopPK) model for tamoxifen and six metabol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0af481d2e814649f5243fccb312076c
https://doi.org/10.1002/cpt.2077

Resveratrol increases glucose induced GLP-1 secretion in mice: a mechanism which contributes to the glycemic control.

Autor: Thi-Mai Anh Dao, Aurélie Waget, Pascale Klopp, Matteo Serino, Christelle Vachoux, Laurent Pechere, Daniel J Drucker, Serge Champion, Sylvain Barthélemy, Yves Barra, Rémy Burcelin, Eric Sérée

Publikováno v: PLoS ONE, Vol 6, Iss 6, p e20700 (2011)

Resveratrol (RSV) is a potent anti-diabetic agent when used at high doses. However, the direct targets primarily responsible for the beneficial actions of RSV remain unclear. We used a formulation that increases oral bioavailability to assess the mec

Externí odkaz: https://doaj.org/article/8b96eb10e8834befa95800ee2058fc4c

Validation of a liquid chromatography–mass spectrometry method to assess the metabolism of bupropion in rat everted gut sacs

Autor: Arellano, C., Philibert, C., Vachoux, C., Woodley, J., Houin, G.

Publikováno v: In Journal of Chromatography B 2005 829(1):50-55

Factors Affecting Tamoxifen Metabolism in Patients With Breast Cancer: Preliminary Results of the French PHACS Study

Autor: Jacques Robert, Alicja Puszkiel, Alexandre Evrard, Etienne Chatelut, Florence Dalenc, Marc Debled, Fabienne Thomas, Caroline Delmas, Laurence Venat-Bouvet, Isabelle Sillet-Bach, Henri Roché, Thomas Filleron, Christelle Vachoux, Etienne Suc, Cécile Arellano, Jean-Christophe Boyer, Valérie Le Morvan, Melanie White-Koning, William Jacot

Publikováno v: Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics, American Society for Clinical Pharmacology and Therapeutics, 2019, 106 (3), pp.585-595. ⟨10.1002/cpt.1404⟩

International audience; In addition to the effect of cytochrome P450 (CYP) 2D6 genetic polymorphisms, the metabolism of tamoxifen may be impacted by other factors with possible consequences on therapeutic outcome (efficacy and toxicity). This analysi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274f222ae7ab868875ee69e1de41fb8f
https://hal.umontpellier.fr/hal-02420919