Zobrazeno 1 - 10
of 2 394
pro vyhledávání: '"Vaccine candidate"'
Autor:
A. S. Kartseva, M. V. Silkina, T. A. Ivashchenko, Ya. O. Romanenko, L. V. Sayapina, V. V. Firstova
Publikováno v:
Проблемы особо опасных инфекций, Vol 0, Iss 3, Pp 15-24 (2024)
Live tularemia vaccine is one of the most effective bacterial vaccines. However, it also has high residual virulence for laboratory animals and may cause adverse reactions in individuals with compromised immune systems. The development of a safe and
Externí odkaz:
https://doaj.org/article/34c531eb01724a0a8c30342d0651fc5b
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Trichinella spiralis (T. spiralis) is a parasitic helminth that causes a globally prevalent neglected zoonotic disease, and worms at different developmental stages (muscle larvae, adult worms, newborn larvae) induce immune attack
Externí odkaz:
https://doaj.org/article/48c6199ff9674c4284f9841ac88cfea2
Autor:
Lu Liu, Peng Cai, Weifang Gu, Xingxun Duan, Shiwen Gao, Xuelian Ma, Yuhui Ma, Siyuan Ma, Guoqing Li, Xiangyu Wang, Kuojun Cai, Yanfeng Wang, Tao Cai, Hongqiong Zhao
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Rhodococcus equi (R. equi) is a zoonotic opportunistic pathogen that mainly causes fatal lung and extrapulmonary abscesses in foals and immunocompromised individuals. To date, no commercial vaccine against R. equi exists. We previously scree
Externí odkaz:
https://doaj.org/article/0f06b5e8b1d2403493feb76104731704
Autor:
Kumar Avishek, Mirza A. Beg, Kavita Vats, Avinash Kumar Singh, Ranadhir Dey, Kamaleshwar P. Singh, Rajesh Kumar Singh, Sreenivas Gannavaram, V. Ramesh, Mohmad Sadik A. Mulla, Upendra Bhatnagar, Sanjay Singh, Hira L. Nakhasi, Poonam Salotra, Angamuthu Selvapandiyan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Centrin1 gene deleted Leishmania donovani parasite (LdCen1 −/− ) was developed and extensively tested experimentally as an intracellular stage-specific attenuated and immunoprotective live parasite vaccine candidate ex vivo using human P
Externí odkaz:
https://doaj.org/article/73ff0db110c94aabb0c13d03ddf5653b
Publikováno v:
Experimental Biology and Medicine, Vol 249 (2024)
Current pneumococcal vaccines, including the pneumococcal polysaccharide (PPV23) and conjugate (PCV13) vaccines, offer protection against specific serotypes but pose risks of serotype replacement that can alter the composition of the nasopharyngeal m
Externí odkaz:
https://doaj.org/article/3d41bb798f634133bfb822f3f53f2a60
Autor:
Qiuling Fu, Xiangmin Han, Chunhua Zhu, Wenlong Jiao, Rongchang Liu, Zhao Feng, Yaping Huang, Zhen Chen, Chunhe Wan, Zhi Lai, Qizhang Liang, Shaohua Shi, Longfei Cheng, Hongmei Chen, Nansong Jiang, Jingliang Su, Guanghua Fu, Yu Huang
Publikováno v:
Poultry Science, Vol 103, Iss 10, Pp 104087- (2024)
ABSTRACT: Duck hepatitis A virus type 3 (DHAV-3) is an infectious virus that is highly fatal to ducklings and causes significant economic losses in the duck industry worldwide. Biosecurity and vaccination are required to control the pathogen. In the
Externí odkaz:
https://doaj.org/article/c576eba86dd2492aba611c7fd9712742
Autor:
Lingzhai Meng, Mengmeng Yu, Suyan Wang, Yuntong Chen, Yuanling Bao, Peng Liu, Xiaoyan Feng, Tana He, Ru Guo, Tao Zhang, Mingxue Hu, Changjun Liu, Xiaole Qi, Kai Li, Li Gao, Yanping Zhang, Hongyu Cui, Yulong Gao
Publikováno v:
Journal of Integrative Agriculture, Vol 23, Iss 5, Pp 1658-1670 (2024)
Avian metapneumovirus (aMPV) is a highly contagious pathogen that causes acute upper respiratory tract diseases in chickens and turkeys, resulting in serious economic losses. Subtype B aMPV has recently become the dominant epidemic strain in China. W
Externí odkaz:
https://doaj.org/article/7d81b6cc1613486a9b9c7e3d81c56585
Autor:
Frederick A. Saul, Brigitte Vulliez-Le Normand, Alexander Boes, Holger Spiegel, Clemens H.M. Kocken, Bart W. Faber, Graham A. Bentley
Publikováno v:
Journal of Structural Biology: X, Vol 10, Iss , Pp 100110- (2024)
Apical Membrane Antigen 1 (AMA1) plays a vital role in the invasion of the host erythrocyte by the malaria parasite, Plasmodium. It is thus an important target for vaccine and anti-malaria therapeutic strategies that block the invasion process. AMA1,
Externí odkaz:
https://doaj.org/article/e07f3fe089b443709f003b70b7311b82
Autor:
Leticia Guzman Ruiz, Alexander M. Zollner, Irene Hoxie, Elsa Arcalis, Florian Krammer, Miriam Klausberger, Alois Jungbauer, Reingard Grabherr
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Vaccination against influenza virus can reduce the risk of influenza by 40% to 60%, they rely on the production of neutralizing antibodies specific to influenza hemagglutinin (HA) ignoring the neuraminidase (NA) as an important surface target. Vaccin
Externí odkaz:
https://doaj.org/article/a94547d6027a4510829c0c1a0b699199