Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Vabren L Watts"'
Publikováno v:
Learned Publishing. 36:85-93
Autor:
Xiaolin Niu, Alicja Bielawska, Marc K. Halushka, Konrad Vandegaer, Majd AlGhatrif, Kathleen L. Gabrielson, Lili A. Barouch, Djahida Bedja, Vabren L. Watts, Karen L. Miller, Karen Fox-Talbot
Publikováno v:
Journal of Cardiovascular Translational Research. 6:436-445
Obesity is associated with increased diastolic stiffness and myocardial steatosis and dysfunction. The impact of aging on the protective effects of caloric restriction (CR) is not clear. We studied 2-month (younger) and 6-7-month (older)-old ob/ob mi
Autor:
Vidhya Sivakumaran, Oscar H. Cingolani, Konrad Vandegaer, Karen L. Miller, Carla LaShannon Ellis, Djahida Bedja, Lili A. Barouch, Nazareno Paolocci, Vabren L. Watts, David A. Kass, Jordan S Leyton-Mange, Kathleen L. Gabrielson, Xiaolin Niu
Publikováno v:
Journal of the American College of Cardiology. 59:1979-1987
Objectives The aim of this study was to determine whether activation of β3-adrenergic receptor (AR) and downstream signaling of nitric oxide synthase (NOS) isoforms protects the heart from failure and hypertrophy induced by pressure overload. Backgr
Autor:
Akinari Hinoki, Timothy A. Fields, Kunie Eguchi, Heigoro Shirai, Evangeline D. Motley, Vabren L. Watts, Hiroyuki Suzuki, Satoru Eguchi, Laura N. Stemmle
Publikováno v:
Hypertension. 53:182-188
Protease-activated receptors (PARs), such as PAR1 and PAR2, have been implicated in the regulation of endothelial NO production. We hypothesized that PAR1 and PAR2 distinctly regulate the activity of endothelial NO synthase through the selective phos
Autor:
Vabren L Watts, Fernando M Sepulveda, Oscar H Cingolani, Xiaolin Niu, Karen L Miller, Rosa Kim, Konrad Vandegaer, Lili A Barouch
Publikováno v:
Circulation Research. 111
Objective: The aim of this study is to identify the mechanisms involved in β3-adrenoreceptor (β3-AR)-dependent cardiac protection via nNOS signaling in cardiomyocytes in the setting of hypertrophy. Background: β3-AR and its downstream signaling pa
Autor:
Majd AlGhatrif, Vabren L Watts, Vidhya Sivakumaran, Xiaolin Niu, Marc Halushka, Karen L Miller, Konrad Vandegaer, Djahida Bedja, Karen Fox-Talbot, Alicja Bielawska, Nazareno Paolocci, Susan Aja, Kathleen L Gabrielson, Lili A Barouch
Publikováno v:
Circulation Research. 111
Introduction: Obesity is associated with increased myocardial steatosis, cardiac dysfunction, mitochondrial uncoupling, and increased apoptosis. Caloric restriction (CR) in older leptin deficient ob/obobese micefails to reduce cardiac steatosis and a
Autor:
Xiaolin, Niu, Vabren L, Watts, Oscar H, Cingolani, Vidhya, Sivakumaran, Jordan S, Leyton-Mange, Carla L, Ellis, Karen L, Miller, Konrad, Vandegaer, Djahida, Bedja, Kathleen L, Gabrielson, Nazareno, Paolocci, David A, Kass, Lili A, Barouch
Publikováno v:
J Am Coll Cardiol
The aim of this study was to determine whether activation of β3-adrenergic receptor (AR) and downstream signaling of nitric oxide synthase (NOS) isoforms protects the heart from failure and hypertrophy induced by pressure overload.β3-AR and its dow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9293fa7c03d34908e72c0490c81b4e6a
https://europepmc.org/articles/PMC3366593/
https://europepmc.org/articles/PMC3366593/
Publikováno v:
The FASEB Journal. 26
Publikováno v:
Circulation Research. 109
Beta3 -adrenergic receptors play a pivotal role in modulating cardiac function, though their precise role in the heart remains controversial. We have recently demonstrated alterations in Ca 2+ -dependent NOS isoforms and decreased NOS activity in lef
Autor:
Lili A. Barouch, A Phan, P P Rainer, Ronghua Yang, Jill E Larson, Karen L. Miller, Vabren L. Watts
Publikováno v:
International journal of obesity (2005). 36(6)
β3-Adrenergic receptors (β3ARs) negatively regulate β-adrenergic signaling via nitric oxide and are dependent on the adipokine leptin for normal expression in adipocytes, thus making β3AR an attractive candidate for cross-talk with leptin in the