DDX5 promotes esophageal squamous cell carcinoma growth through sustaining VAV3 mRNA stability.

Autor: Shi Y; The Pathophysiology Department, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.; Tianjian Laboratory for Advanced Biomedical Sciences, Zhengzhou, Henan, China.; China-US (Henan) Hormel Cancer Institute, Zhengzhou, China.; Department of Molecule and Pathology, Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, Henan, China., Wang J; Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China., Yuan Q; The Pathophysiology Department, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.; Tianjian Laboratory for Advanced Biomedical Sciences, Zhengzhou, Henan, China.; China-US (Henan) Hormel Cancer Institute, Zhengzhou, China., Chen Y; The Pathophysiology Department, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China., Zhao M; The Pathophysiology Department, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China., Li X; The Pathophysiology Department, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China., Wang Z; The Pathophysiology Department, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China., Zhou H; The Pathophysiology Department, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China., Zhu F; The Pathophysiology Department, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China., Wei B; Department of Molecule and Pathology, Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, Henan, China., Jiang Y; The Pathophysiology Department, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.; Tianjian Laboratory for Advanced Biomedical Sciences, Zhengzhou, Henan, China.; China-US (Henan) Hormel Cancer Institute, Zhengzhou, China.; Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China.; State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou, Henan, China., Zhao J; The Pathophysiology Department, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.; State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou, Henan, China.; Provincial Cooperative Innovation Center for Cancer Chemoprevention, Zhengzhou University, Zhengzhou, Henan, China.; Cancer Chemoprevention International Collaboration Laboratory, Zhengzhou, Henan, China., Qiao Y; The Pathophysiology Department, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China. yanqiao@zzu.edu.cn., Dong Z; The Pathophysiology Department, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China. zgdong@hci-cn.org.; Tianjian Laboratory for Advanced Biomedical Sciences, Zhengzhou, Henan, China. zgdong@hci-cn.org.; China-US (Henan) Hormel Cancer Institute, Zhengzhou, China. zgdong@hci-cn.org.; State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou, Henan, China. zgdong@hci-cn.org.; Cancer Chemoprevention International Collaboration Laboratory, Zhengzhou, Henan, China. zgdong@hci-cn.org., Liu K; The Pathophysiology Department, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China. kdliu@zzu.edu.cn.; Tianjian Laboratory for Advanced Biomedical Sciences, Zhengzhou, Henan, China. kdliu@zzu.edu.cn.; China-US (Henan) Hormel Cancer Institute, Zhengzhou, China. kdliu@zzu.edu.cn.; Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China. kdliu@zzu.edu.cn.; State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou, Henan, China. kdliu@zzu.edu.cn.; Provincial Cooperative Innovation Center for Cancer Chemoprevention, Zhengzhou University, Zhengzhou, Henan, China. kdliu@zzu.edu.cn.; Cancer Chemoprevention International Collaboration Laboratory, Zhengzhou, Henan, China. kdliu@zzu.edu.cn.

Publikováno v: Oncogene [Oncogene] 2024 Oct; Vol. 43 (44), pp. 3240-3254. Date of Electronic Publication: 2024 Sep 17.

VAV2 orchestrates the interplay between regenerative proliferation and ribogenesis in both keratinocytes and oral squamous cell carcinoma.

Autor: Fernández-Parejo N; Centro de Investigación del Cáncer and Instituto de Biología Molecular del Cáncer, CSIC and Universidad de Salamanca, 37007, Salamanca, Spain.; Centro de Investigación Biomédica en Red de Cáncer, 28029, Madrid, Spain., Lorenzo-Martín LF; Centro de Investigación del Cáncer and Instituto de Biología Molecular del Cáncer, CSIC and Universidad de Salamanca, 37007, Salamanca, Spain.; Centro de Investigación Biomédica en Red de Cáncer, 28029, Madrid, Spain.; Laboratory of Stem Cell Bioengineering, École Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland., García-Pedrero JM; Centro de Investigación Biomédica en Red de Cáncer, 28029, Madrid, Spain.; Hospital Universitario Central de Asturias and Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Instituto Universitario de Oncología del Principado de Asturias, University of Oviedo, 33011, Oviedo, Spain., Rodrigo JP; Centro de Investigación Biomédica en Red de Cáncer, 28029, Madrid, Spain.; Hospital Universitario Central de Asturias and Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Instituto Universitario de Oncología del Principado de Asturias, University of Oviedo, 33011, Oviedo, Spain., Dosil M; Centro de Investigación del Cáncer and Instituto de Biología Molecular del Cáncer, CSIC and Universidad de Salamanca, 37007, Salamanca, Spain. mdosil@usal.es.; Centro de Investigación Biomédica en Red de Cáncer, 28029, Madrid, Spain. mdosil@usal.es., Bustelo XR; Centro de Investigación del Cáncer and Instituto de Biología Molecular del Cáncer, CSIC and Universidad de Salamanca, 37007, Salamanca, Spain. xbustelo@usal.es.; Centro de Investigación Biomédica en Red de Cáncer, 28029, Madrid, Spain. xbustelo@usal.es.

Publikováno v: Scientific reports [Sci Rep] 2024 Feb 19; Vol. 14 (1), pp. 4060. Date of Electronic Publication: 2024 Feb 19.

Hub metastatic gene signature and risk score of breast cancer patients with small tumor sizes using WGCNA.

Autor: Chang YT; School of Public Health, National Defense Medical Center, Taipei City, Taiwan., Hong ZJ; Division of General Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Chenggong Rd., Neihu Dist., Taipei City, 114202, Taiwan., Tsai HH; Division of General Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Chenggong Rd., Neihu Dist., Taipei City, 114202, Taiwan., Feng AC; Division of General Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Chenggong Rd., Neihu Dist., Taipei City, 114202, Taiwan., Huang TY; School of Public Health, National Defense Medical Center, Taipei City, Taiwan., Yu JC; Division of General Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Chenggong Rd., Neihu Dist., Taipei City, 114202, Taiwan., Hsu KF; Division of General Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Chenggong Rd., Neihu Dist., Taipei City, 114202, Taiwan., Huang CC; Department of Surgery, Taipei Veterans General Hospital, No.201, Sec. 2, Shipai Rd., Beitou District, Taipei City, 11217, Taiwan.; Comprehensive Breast Health Center, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Rd., Beitou District, Taipei City, 11217, Taiwan.; Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, No. 17, Xuzhou Rd., Taipei City, 100, Taiwan., Lin WZ; AIoT Center, Tri-Service General Hospital, Taipei City, Taiwan., Chu CM; School of Public Health, National Defense Medical Center, Taipei City, Taiwan., Liang CM; Division of General Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Chenggong Rd., Neihu Dist., Taipei City, 114202, Taiwan., Liao GS; Division of General Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Chenggong Rd., Neihu Dist., Taipei City, 114202, Taiwan. liaogs20371@gmail.com.

Publikováno v: Breast cancer (Tokyo, Japan) [Breast Cancer] 2024 Nov; Vol. 31 (6), pp. 1114-1129. Date of Electronic Publication: 2024 Aug 27.

VAV3 in human cancers: Mechanism and clinical implication.

Autor: Al-Hawary SIS; Departemnt of Business Administration, Business School, Al-Bayt University, P.O.BOX 130040, Mafraq 25113, Jordan., Alsalamy A; College of Engineering, Imam Ja'afar Al-Sadiq University, Al-Muthanna 66002, Iraq., Gupta R; Institute of Pharmaceutical Research, GLA University, District-Mathura, U.P., 281406, India., Alsaab HO; Department of Pharmaceutics and Pharmaceutical Technology, Taif University, Taif 21944, Saudi Arabia., Hjazi A; Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia., Edilboyev U; Department of Engineering Graphics and Design Theory, Tashkent Institute of Irrigation and Agricultural Mechanization Engineers, National Research University, Tashkent, Uzbekistan., Ramadan MF; College of Dentistry, Al-Ayen University, Thi-Qar, Iraq ‏., Hussien BM; Medical Laboratory Technology Department, College of Medical Technology, The Islamic University, Najaf, Iraq., Ahmed M; Medical Technical College, Al-Farahidi University, Baghdad, Iraq., Hosseini-Fard SR; Biochemistry Department, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: Rhoseinifard@razi.tums.ac.ir.

Publikováno v: Pathology, research and practice [Pathol Res Pract] 2023 Aug; Vol. 248, pp. 154681. Date of Electronic Publication: 2023 Jul 13.

The fusion oncogene VAV1-MYO1F triggers aberrant T-cell receptor signaling in vivo and drives peripheral T-cell lymphoma in mice.

Autor: Morrish E; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), Technical University of Munich, Munich, Germany.; German Cancer Consortium (DKTK), partner site Munich, Munich, Germany., Wartewig T; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), Technical University of Munich, Munich, Germany.; Center of Molecular and Cellular Oncology, Yale School of Medicine, Yale University, New Haven, CT, USA., Kratzert A; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), Technical University of Munich, Munich, Germany., Rosenbaum M; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), Technical University of Munich, Munich, Germany., Steiger K; German Cancer Consortium (DKTK), partner site Munich, Munich, Germany.; Comparative Experimental Pathology, Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany., Ruland J; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), Technical University of Munich, Munich, Germany.; German Cancer Consortium (DKTK), partner site Munich, Munich, Germany.; German Center for Infection Research (DZIF), partner site Munich, Munich, Germany.

Publikováno v: European journal of immunology [Eur J Immunol] 2023 Mar; Vol. 53 (3), pp. e2250147. Date of Electronic Publication: 2023 Feb 15.