Zobrazeno 1 - 10
of 71
pro vyhledávání: '"VSMC, Vascular smooth muscle cell"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Abdominal aortic aneurysms (AAAs) account for up to 8% of deaths in men aged 65 years and over and 2.2% of women. Patients with AAAs often have atherosclerosis, and intimal atherosclerosis is generally present in AAAs. Accordingly, AAAs are considere
Externí odkaz:
https://doaj.org/article/04a1a382ce59481da1c61714e2f4ba52
Autor:
Melanie A. Kimm, Vanessa Franziska Schmidt, Max L.A. Ebert, Lena Pfaff, Anne von Thaden, Moritz Wildgruber
Publikováno v:
JACC: Basic to Translational Science
Central Illustration
Highlights • Neointimal hyperplasia is the major factor contributing to restenosis after angioplasty procedures. • Multiple animal models exist to study basic and translational aspects of restenosis formation. • Animal
Highlights • Neointimal hyperplasia is the major factor contributing to restenosis after angioplasty procedures. • Multiple animal models exist to study basic and translational aspects of restenosis formation. • Animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88165634a122d3faf899cdcac81ed099
https://doi.org/10.1016/j.jacbts.2021.06.006
https://doi.org/10.1016/j.jacbts.2021.06.006
Autor:
Andrea Morelli, Valentina Valenti, Giuseppe Biondi-Zoccai, Sebastiano Sciarretta, Maurizio Forte, Leonardo Schirone, Alessandra Iaccarino, Francesco Giosuè Irace, Roberto Carnevale, Mariangela Peruzzi, Simona Bartimoccia, Fabio Miraldi, Umberto Benedetto, Antonino G.M. Marullo, Giacomo Frati, Vittoria Cammisotto, Ernesto Greco, Ruggero De Paulis, Cristina Nocella, Sonia Schiavon
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • Because autophagy and Nox2 activation were identified as possible mechanisms for preservation of vessel integrity, they could be useful biomarkers to predict risk of aneurysm rupture by detecting the presence of a
Highlights • Because autophagy and Nox2 activation were identified as possible mechanisms for preservation of vessel integrity, they could be useful biomarkers to predict risk of aneurysm rupture by detecting the presence of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3521b35a73c9daf4fe532db8bea8b67
http://europepmc.org/articles/PMC8559314
http://europepmc.org/articles/PMC8559314
Publikováno v:
JACC: Basic to Translational Science
Central Illustration
Highlights • Vascular calcification is a highly regulated, cell-mediated process that is strongly associated with CKD and confers increased risk for incident CV events. • Multiple pathways link vascular calcification wit
Highlights • Vascular calcification is a highly regulated, cell-mediated process that is strongly associated with CKD and confers increased risk for incident CV events. • Multiple pathways link vascular calcification wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e372c695df3f3abc3d2cbb7eb7aeb0
https://doi.org/10.1016/j.jacbts.2020.02.002
https://doi.org/10.1016/j.jacbts.2020.02.002
Autor:
Zhenyu Luo, Cuifu Yu, Renjie Chai, Hongbiao Huang, Yangshuo Jin, Ningning Liu, Xiaohong Xia, Tumei Hu, Bijun Du, Jielei Gu, Qiong Xu, Shiming Liu, Wenchao Ou, Xiaolin Liu
Publikováno v:
The Journal of Biological Chemistry
The underlying mechanism of neointima formation remains unclear. Ubiquitin-specific peptidase 10 (USP10) is a deubiquitinase that plays a major role in cancer development and progression. However, the function of USP10 in arterial restenosis is unkno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b3a7a44021dfe977b403f744520a584
http://europepmc.org/articles/PMC8524199
http://europepmc.org/articles/PMC8524199
Autor:
Chenfeng Mao, Peiyi Luo, Min Zhang, Mazdak Ehteramyan, Lingfang Zeng, Yi Li, Andriana Margariti, Wei Kong, Lei Huang, Yijie Gong, Alberto Smith, Yingtang Gao, Angshumonik Angbohang, Ajay M. Shah, Tong Li, Yi Fu, Wenduo Gu, Jose Morales, Yue Zhao
Publikováno v:
Angbohang, A, Huang, L, Li, Y, Zhao, Y, Gong, Y, Fu, Y, Mao, C, Morales, J, Luo, P, Ehteramyan, M, Gao, Y, Margariti, A, Gu, W, Zhang, M, Smith, A, Shah, A M, Li, T, Kong, W & Zeng, L 2021, ' X-box binding protein 1-mediated COL4A1s secretion regulates communication between vascular smooth muscle and stem/progenitor cells ', The Journal of biological chemistry, vol. 296, 100541 . https://doi.org/10.1016/j.jbc.2021.100541
The Journal of Biological Chemistry
The Journal of Biological Chemistry
Vascular smooth muscle cells (VSMCs) contribute to the deposition of extracellular matrix proteins (ECMs), including Type IV collagen, in the vessel wall. ECMs coordinate communication among different cell types, but mechanisms underlying this commun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871010bbd4eea11112b2cad2ae460262
https://pure.qub.ac.uk/en/publications/xbox-binding-protein-1mediated-col4a1s-secretion-regulates-communication-between-vascular-smooth-muscle-and-stemprogenitor-cells(5b4be80d-b6c3-471b-9d4e-e23b3920a7ce).html
https://pure.qub.ac.uk/en/publications/xbox-binding-protein-1mediated-col4a1s-secretion-regulates-communication-between-vascular-smooth-muscle-and-stemprogenitor-cells(5b4be80d-b6c3-471b-9d4e-e23b3920a7ce).html
Autor:
Ebert, Max L A, Schmidt, Vanessa F, Pfaff, Lena, von Thaden, Anne, Kimm, Melanie A, Wildgruber, Moritz
Publikováno v:
JACC Basic to translational science 6(11), 900-917 (2021). doi:10.1016/j.jacbts.2021.06.006
The process of restenosis is based on the interplay of various mechanical and biological processes triggered by angioplasty-induced vascular trauma. Early arterial recoil, negative vascular remodeling, and neointimal formation therefore limit the lon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10678::dc85333e28de216e8209e7dde8278277
https://pub.dzne.de/record/163653
https://pub.dzne.de/record/163653
Publikováno v:
JACC: Basic to Translational Science
Highlights • Accelerated atherosclerosis is common when SVGs, but not arterial grafts, are used for myocardial revascularization during CABG. • This review will provide an overview of the available data on the most commonly used conduits in CABG,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fb244a8a5b6287ac0fe0975229d03f
https://pubmed.ncbi.nlm.nih.gov/33997524
https://pubmed.ncbi.nlm.nih.gov/33997524
Autor:
Mingying Xue, Yue Wu, Liangming Liu, Zisen Zhang, Xiang Xinming, Jie Zhang, Chenyang Duan, Qing-Hui Li, Kunlun Tian, Tao Li, Li Wang
Publikováno v:
Redox Biology, Vol 37, Iss, Pp 101706-(2020)
Redox Biology
Redox Biology
Vascular dysfunctions such as vascular hyporeactivity following ischemic/hypoxic injury are a major cause of death in injured patients. In this study, we showed that treatment with mitochondrial division inhibitor 1 (Mdivi-1), a selective inhibitor o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31007e7f9f465b82a01fcb6bd310837
http://www.sciencedirect.com/science/article/pii/S2213231720309113
http://www.sciencedirect.com/science/article/pii/S2213231720309113
Autor:
Gabriel Bedoya, Juan Eugenio Ochoa, Dagnovar Aristizábal, Juan E. Gallo, Oliver K. Clay, M. M. Correa, Gianfranco Parati, Helen R. Warren, Elizabeth Misas, Jaime Gallo-Villegas, Mark J. Caulfield, Juan G. McEwen
Publikováno v:
International Journal of Cardiology. Hypertension, Vol 7, Iss, Pp 100050-(2020)
International Journal of Cardiology Hypertension
International Journal of Cardiology Hypertension
Background The band 9p21.3 contains an established genomic risk zone for cardiovascular disease (CVD). Since the initial 2007 Wellcome Trust Case Control Consortium study (WTCCC), the increased CVD risk associated with 9p21.3 has been confirmed by mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b7b324eaf9723f91fda2ea87db22ea1
https://pubmed.ncbi.nlm.nih.gov/33330845
https://pubmed.ncbi.nlm.nih.gov/33330845