Zobrazeno 1 - 10
of 2 121
pro vyhledávání: '"VSMC"'
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 54, Iss , Pp 101500- (2024)
Abdominal aortic aneurysms (AAAs) are characterized by permanent dilatation of the abdominal aorta, which is accompanied by inflammation, degradation of the extracellular matrix (ECM) and disruption of vascular smooth muscle cell (VSMC) homeostasis.
Externí odkaz:
https://doaj.org/article/69b16c7fbc2745cb90c09aa571e188b7
Autor:
T. Lomonaco, E. Persiani, D. Biagini, I. Gisone, E. Ceccherini, A. Cecchettini, A. Corti, S. Ghimenti, F. Di Francesco, V. Castelvetro, F. Vozzi
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 282, Iss , Pp 116695- (2024)
Microplastics (MPs) are recognized as a major environmental problem due to their ubiquitous presence in ecosystems and bioaccumulation in food chains. Not only humans are continuously exposed to these pollutants through ingestion and inhalation, but
Externí odkaz:
https://doaj.org/article/fc4d21b5f0ac4abaa4834dce4360a259
Autor:
Wenjing Yang, Chunqing Lu, Fang Chu, Keming Bu, Hao Ma, Qiaoyu Wang, Zhe Jiao, Sheng Wang, Xiyue Yang, Yanhui Gao, Dianjun Sun, Hongna Sun
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 281, Iss , Pp 116681- (2024)
Fluoride exposure has been implicated as a potential risk factor for hypertension, but the underlying mechanisms remain unclear. This study investigated the role of the RhoA/ROCK signaling pathway in fluoride-induced hypertension. Male Wistar rats we
Externí odkaz:
https://doaj.org/article/7d4d3aa7039f43c5bcd50ab8d4a0775e
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116858- (2024)
The roles and mechanisms of A-kinase anchoring protein 1 (AKAP1) in vascular smooth muscle cell (VSMC) phenotypic modulation and neointima formation are currently unknown. AKAP1 is a mitochondrial PKA-anchored protein and maintains mitochondrial home
Externí odkaz:
https://doaj.org/article/6db61bcd05c9499fb0f325d13604a17a
Publikováno v:
Translation, Vol 12, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/519fe6d90b40481ca62fc0c5413b67e1
Publikováno v:
Open Medicine, Vol 18, Iss 1, Pp 1-11 (2023)
This study aims to investigate the impact of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) on vascular calcification in rats. The rationale behind studying ENPP1’s role in vascular calcification lies in its potential to modulate calcif
Externí odkaz:
https://doaj.org/article/c0d0d14519f546979c71328bac7faa50
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
BackgroundCarotid artery atherosclerosis is a major cause of ischemic stroke, and ischemic stroke is the leading cause of morbidity and mortality worldwide. Unfortunately, the reason for the build-up of atherosclerosis plaque is unknown. The miRNA-29
Externí odkaz:
https://doaj.org/article/2e8fe9c2ce784e939ee9388875d3d675
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-19 (2023)
Abstract Background Macrophage-like transformation of vascular smooth muscle cells (VSMCs) is a risk factor of atherosclerosis (AS) progression. Transcription factor homeobox A1 (HOXA1) plays functional roles in differentiation and development. This
Externí odkaz:
https://doaj.org/article/c57bca6c1f874556bf3f6b6f4aa6e9b0
Publikováno v:
Thoracic Cancer, Vol 14, Iss 22, Pp 2158-2167 (2023)
Abstract Background Vascular smooth muscle cells (VSMCs) are the predominant cell type of the aortic middle layer, the abnormal number or function of which has been demonstrated to have a role in thoracic aortic aneurysm (TAA). Here, this study aimed
Externí odkaz:
https://doaj.org/article/96bc6925473e477fa2ce6fb52e2b2f08