Zobrazeno 1 - 10
of 41
pro vyhledávání: '"VPA, valproic acid"'
Autor:
E. Isidahome, M. San Gabriel
Publikováno v:
European Psychiatry, Vol 65, Pp S346-S346 (2022)
Introduction Valproic acid (VPA) is a valuable treatment for bipolar disorder, schizoaffective disorder, and agitation1. However, potential side-effects include sedation, headaches, tremors, ataxia, gastrointestinal issues, neural tube defect, 3 and
Externí odkaz:
https://doaj.org/article/00f4234f8c1848d39f1813cc53dceeb9
Publikováno v:
Saudi Pharmaceutical Journal, Vol 29, Iss 5, Pp 418-426 (2021)
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal : SPJ
Objectives Epilepsy is a neurological disease characterized by sudden, abnormal, and hyper- discharges in the central nervous system (CNS). Valproic acid (VPA) is commonly used as a broad-spectrum antiepileptic therapeutic. However, in many cases, pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf62cd47c94441001c4de4abad26c3f9
https://doi.org/10.1016/j.jsps.2021.04.002
https://doi.org/10.1016/j.jsps.2021.04.002
Publikováno v:
eNeurologicalSci
eNeurologicalSci, Vol 22, Iss, Pp 100298-(2021)
eNeurologicalSci, Vol 22, Iss, Pp 100298-(2021)
Background Angelman syndrome (AS) is neurodevelopmental disorder, causal gene of which is maternally expressed UBE3A. A majority of patients results from the large deletion of relevant chromosome which includes GABAA receptor subunit genes (GABARs) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93da5acf5256bb0212161d3041c4953
https://pubmed.ncbi.nlm.nih.gov/33313428
https://pubmed.ncbi.nlm.nih.gov/33313428
Publikováno v:
JACC: Basic to Translational Science
Summary Chemical modifications to nucleosomal DNA and histone tails greatly influence transcription of adjacent and distant genes, a mode of gene regulation referred to as epigenetic control. Here, the authors summarize recent findings that have illu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b359704a913de10a2dfafe083b0d4149
http://europepmc.org/articles/PMC6234501
http://europepmc.org/articles/PMC6234501
Publikováno v:
Epilepsy & Behavior Case Reports
Epilepsy and Behavior Case Reports, Vol 11, Iss, Pp 47-51 (2019)
Epilepsy and Behavior Case Reports, Vol 11, Iss, Pp 47-51 (2019)
Ictal syncope is a rare phenomenon that occurs in association with 0.002–0.4% of seizures. In the absence of other symptoms, seizures presenting with syncope may be challenging to diagnose. We report a case of a previously healthy male who develope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1ded62b63728bf6bbe55184b93a8d6
http://europepmc.org/articles/PMC6327908
http://europepmc.org/articles/PMC6327908
Publikováno v:
Practical Laboratory Medicine, Vol 10, Iss C, Pp 15-20 (2018)
Practical Laboratory Medicine
Practical Laboratory Medicine
We present a simple and fast high-performance liquid chromatography method with fluorescence detection for the determination of the antiepileptic drug perampanel in human plasma. The chromatographic separation was performed on a Kinetex PFP (100 × 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7ce060897a1c004dfcadfca9820bf3
https://doi.org/10.1016/j.plabm.2017.11.003
https://doi.org/10.1016/j.plabm.2017.11.003
Autor:
Paulína Káňovičová, Petra Čermáková, Dominika Kubalová, Lenka Bábelová, Petra Veselá, Martin Valachovič, Jakub Zahumenský, Anton Horváth, Jan Malínský, Mária Balážová
Publikováno v:
The Journal of Biological Chemistry
Barth syndrome (BTHS) is an inherited mitochondrial disorder characterized by a decrease in total cardiolipin and the accumulation of its precursor monolysocardiolipin due to the loss of the transacylase enzyme tafazzin. However, the molecular basis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde4a52087aa3b610bb0be1c6a81a9d6
https://doi.org/10.1016/j.jbc.2021.101462
https://doi.org/10.1016/j.jbc.2021.101462
Publikováno v:
Epilepsy & Behavior Reports, Vol 12, Iss, Pp-(2019)
Epilepsy & Behavior Reports
Epilepsy & Behavior Reports
Patients with mutations in the POLG-1 gene often are afflicted with drug-resistant seizures at an early age and have an increased risk of valproic acid-induced acute liver failure. Severe valproate hepatotoxicity most commonly arises in children with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd564f7a9da35d247a0315b84b9ee66
http://www.sciencedirect.com/science/article/pii/S2589986419301364
http://www.sciencedirect.com/science/article/pii/S2589986419301364
Akademický článek
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Publikováno v:
Epilepsy and Behavior Case Reports, Vol 8, Iss C, Pp 108-110 (2017)
Epilepsy & Behavior Case Reports
Epilepsy & Behavior Case Reports
Valproic acid (VPA) is a broad-spectrum antiseizure drug used for a variety of clinical conditions, such as epilepsy and mood disorders. Drug-induced hypersensitivity syndrome (DRESS) accompanied by hyponatremia, thrombocytopenia, hypoalbuminemia and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec153cf079350aefd60f1fbcd271170
https://doi.org/10.1016/j.ebcr.2017.06.003
https://doi.org/10.1016/j.ebcr.2017.06.003