Zobrazeno 1 - 10
of 114
pro vyhledávání: '"VLADIMIR S. SPIEGELMAN"'
Autor:
Carson A. Wills, Xiaoming Liu, Longgui Chen, Yuanjun Zhao, Zhenqiu Liu, Vladimir S. Spiegelman, Jeffrey Sundstrom, Hong-Gang Wang
Publikováno v:
Genes and Diseases, Vol 11, Iss 4, Pp 101017- (2024)
Externí odkaz:
https://doaj.org/article/5f8937637a8f41b695486dea0b968e0c
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Neuroblastoma (NB) is the most common extracranial solid pediatric cancer, and is one of the leading causes of cancer-related deaths in children. Despite the current multi-modal treatment regimens, majority of patients with advanced-stage NBs develop
Externí odkaz:
https://doaj.org/article/a7aab62499904f378ad7022f839ed4d7
Autor:
Stephanie L. Baringer, Kondaiah Palsa, Vladimir S. Spiegelman, Ian A. Simpson, James R. Connor
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-13 (2023)
Abstract Background Apo- (iron free) and holo- (iron bound) transferrin (Tf) participate in precise regulation of brain iron uptake at endothelial cells of the blood–brain barrier. Apo-Tf indicates an iron-deficient environment and stimulates iron
Externí odkaz:
https://doaj.org/article/b95d22665c3c4e128ec7e5ea69f71b76
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Wnt/β-catenin signaling controls cell division and lineage specification during embryonic development, and is crucial for stem cells maintenance and gut tissue regeneration in adults. Aberrant activation of Wnt/β-catenin signaling is
Externí odkaz:
https://doaj.org/article/8f9bbf6a9f1e4a6bbc8f46f549056a6f
Autor:
Nicole Betson, Mohammed Hajahmed, Tsige Gebretsadek, Kenneth Ndebele, H. Anwar Ahmad, Paul B. Tchounwou, Vladimir S. Spiegelman, Felicite K. Noubissi
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 12, Pp 816-829 (2022)
Abstract Although colorectal cancer (CRC) treatment has seen a remarkable improvement in the recent years, many patients will develop metastasis due to the resistance of cancer cells to chemotherapeutics. Targeting mechanisms driving the resistance o
Externí odkaz:
https://doaj.org/article/e843205372494211a437d7ed6c4aee92
Autor:
Irina A. Elcheva, Chethana P. Gowda, Daniel Bogush, Svetlana Gornostaeva, Anna Fakhardo, Neil Sheth, Kathleen M. Kokolus, Arati Sharma, Sinisa Dovat, Yasin Uzun, Todd D. Schell, Vladimir S. Spiegelman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Insulin-like growth factor 2 mRNA-binding proteins (IGF2BP1, IGF2BP2, and IGF2BP3) are a family of RNA-binding proteins that play an essential role in the development and disease by regulating mRNA stability and translation of critical regulators of
Externí odkaz:
https://doaj.org/article/3d55f5781c1a40d1bb5c95fbf8cfd495
Publikováno v:
Cancer Reports, Vol 5, Iss 10, Pp n/a-n/a (2022)
Abstract Background Acute myeloid leukemia (AML) is a heterogeneous disease in both children and adults. Although it is well‐known that adult and pediatric AMLs are genetically distinct diseases, the driver genes for high‐risk pediatric and adult
Externí odkaz:
https://doaj.org/article/33db2c4cef61493d9c9853c256487d2d
Autor:
Tithi Roy, Samuel T. Boateng, Sergette Banang-Mbeumi, Pankaj K. Singh, Pratik Basnet, Roxane-Cherille N. Chamcheu, Federico Ladu, Isabel Chauvin, Vladimir S. Spiegelman, Ronald A. Hill, Konstantin G. Kousoulas, Bolni Marius Nagalo, Anthony L. Walker, Jean Fotie, Siva Murru, Mario Sechi, Jean Christopher Chamcheu
Publikováno v:
Data in Brief, Vol 35, Iss , Pp 106858- (2021)
This article contains supplemental datasets of the recently published related research article “Synthesis, Inverse Docking-Assisted Identification and in vitro Biological Characterization of Flavonol-based Analogs of Fisetin as c-Kit, CDK2 and mTOR
Externí odkaz:
https://doaj.org/article/8f9eb6ff82c7476a93275e6a6773652e
Autor:
Jason M. Biegel, Mayura Dhamdhere, Shuang Gao, Chethana P. Gowda, Yuka Imamura Kawasawa, Vladimir S. Spiegelman
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Gain at chromosome 17q21 in neuroblastoma is associated with a poor prognosis, independent of MYCN amplification status. Several potential proto-oncogenes have been identified in this region, one of them—insulin-like growth-factor-2 mRNA binding pr
Externí odkaz:
https://doaj.org/article/74caff8d27094cf3bbda96c572fc8679
Publikováno v:
Informatics in Medicine Unlocked, Vol 25, Iss , Pp 100701- (2021)
Although high-risk neuroblastoma (HR-NB) is clinically heterogeneous, it is treated in a similar fashion without additional risk stratification. Based on the 4 copy-number profiles with 556 HR-NB subjects and 14 potential risk factors of neuroblastom
Externí odkaz:
https://doaj.org/article/41fc59f222cd49548b73b65b8d3ae474