Zobrazeno 1 - 10
of 34
pro vyhledávání: '"VIVIANA DE ROSA"'
Autor:
Jelena Dimitrov, Maurizio Maddalena, Cristina Terlizzi, Giovanna G. Altobelli, Sara Pellegrino, Tayyaba Mehmood, Viviana De Rosa, Francesca Iommelli, Silvana Del Vecchio
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionNeutrophil extracellular traps (NETs) are complex structures released by activated neutrophils that may modulate different steps of the metastatic cascade. The aim of our study was to investigate how NETs can modulate the adhesion propert
Externí odkaz:
https://doaj.org/article/6b86c4d85e2b472fa071fc82e8e5fd13
Autor:
Caterina De Rosa, Viviana De Rosa, Concetta Tuccillo, Virginia Tirino, Luisa Amato, Federica Papaccio, Davide Ciardiello, Stefania Napolitano, Giulia Martini, Fortunato Ciardiello, Floriana Morgillo, Francesca Iommelli, Carminia Maria Della Corte
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Osimertinib is a third-generation tyrosine kinase inhibitor clinically approved for first-line treatment of EGFR-mutant non-small cell lung cancer (NSCLC) patients. Although an impressive drug response is initially observed, in most of tumor
Externí odkaz:
https://doaj.org/article/7d656ea1f95540b390fad3f80f70a223
Autor:
Cristina Terlizzi, Viviana De Rosa, Francesca Iommelli, Antonio Pezone, Giovanna G. Altobelli, Maurizio Maddalena, Jelena Dimitrov, Caterina De Rosa, Carminia Maria Della Corte, Vittorio Enrico Avvedimento, Silvana Del Vecchio
Publikováno v:
Cancer & Metabolism, Vol 11, Iss 1, Pp 1-11 (2023)
Abstract Background ATM is a multifunctional serine/threonine kinase that in addition to its well-established role in DNA repair mechanisms is involved in a number of signaling pathways including regulation of oxidative stress response and metabolic
Externí odkaz:
https://doaj.org/article/e83d3991835d4c898a45587c3d859097
Autor:
Hamid Heydari Sheikhhossein, Francesca Iommelli, Natalia Di Pietro, Maria Cristina Curia, Adriano Piattelli, Rosanna Palumbo, Giovanni N. Roviello, Viviana De Rosa
Publikováno v:
Vaccines, Vol 12, Iss 5, p 519 (2024)
Cancer remains one of the main causes of death in the world due to its increasing incidence and treatment difficulties. Although significant progress has been made in this field, innovative approaches are needed to reduce tumor incidence, progression
Externí odkaz:
https://doaj.org/article/2a7525af2fbc4e9495b2bbc3753537d4
Autor:
Caterina De Rosa, Francesca Iommelli, Viviana De Rosa, Giuseppe Ercolano, Federica Sodano, Concetta Tuccillo, Luisa Amato, Virginia Tirino, Annalisa Ariano, Flora Cimmino, Gaetano di Guida, Gennaro Filosa, Alessandra di Liello, Davide Ciardiello, Erika Martinelli, Teresa Troiani, Stefania Napolitano, Giulia Martini, Fortunato Ciardiello, Federica Papaccio, Floriana Morgillo, Carminia Maria Della Corte
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 809 (2024)
Background: Lung cancer (LC), including both non-small (NSCLC) and small (SCLC) subtypes, is currently treated with a combination of chemo- and immunotherapy. However, predictive biomarkers to identify high-risk patients are needed. Here, we explore
Externí odkaz:
https://doaj.org/article/1b66bc9fe5414c49811d29401c6e567b
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 2, Iss 1, Pp 36-47 (2021)
The occurrence of phenotype switch from an epithelial to a mesenchymal cell state during the activation of the epithelial mesenchymal transition (EMT) program in cancer cells has been closely associated with the generation of invasive tumor cells tha
Externí odkaz:
https://doaj.org/article/ab3bf58d6b614ec6979258a052eafc00
Autor:
Marcello Monti, Francesca Iommelli, Viviana De Rosa, Maria Vincenza Carriero, Roberta Miceli, Rosa Camerlingo, Giovanni Di Minno, Silvana Del Vecchio
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171362 (2017)
Neutrophil extracellular traps (NETs), originally recognized as a host defense mechanism, were reported to promote thrombosis and metastatic dissemination of cancer cells. Here we tested the role of integrins α5β1 and ανβ3 in the adhesion of can
Externí odkaz:
https://doaj.org/article/944a5bb624384373a76bf31c39b94e50
Autor:
Silvana Del Vecchio, Rosa Fonti, Mariarosaria Panico, Marcello Monti, Cristina Terlizzi, Viviana De Rosa, Francesca Iommelli
Supplementary Table 1. Levels of IP3R3 and signaling mediators by densitometric analysis of western blots. The optical density of each band was normalized to the same parameter derived from the corresponding tubulin control using ImageJ software and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d70f7e6c1854b70908db464f5b15ef4
https://doi.org/10.1158/1078-0432.22470858
https://doi.org/10.1158/1078-0432.22470858
Autor:
Silvana Del Vecchio, Rosa Fonti, Mariarosaria Panico, Marcello Monti, Cristina Terlizzi, Viviana De Rosa, Francesca Iommelli
Purpose: Our aim was to test whether imaging with 18F-fluorothymidine (18F-FLT) PET/CT was able to detect the combined effects of EGFR and MET inhibitors in oncogene-driven non–small cell lung cancer (NSCLC) and to elucidate the mechanisms underlyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10df72e707e22e31c154a229a1c9b83b
https://doi.org/10.1158/1078-0432.c.6527706
https://doi.org/10.1158/1078-0432.c.6527706
Autor:
Silvana Del Vecchio, Rosa Fonti, Mariarosaria Panico, Marcello Monti, Cristina Terlizzi, Viviana De Rosa, Francesca Iommelli
Supplementary Figure S1. Toxicity of combined treatment with erlotinib and crizotinib in H820 cells. Cell toxicity was determined by MTS assay in H820 cells treated with increasing doses of erlotinib and crizotinib used alone or in combination at 1:1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612871ef3f5a72575765e47562bb96c0
https://doi.org/10.1158/1078-0432.22470864
https://doi.org/10.1158/1078-0432.22470864