Zobrazeno 1 - 10
of 3 345
pro vyhledávání: '"VIRUS ENTRY"'
Autor:
Shiau‐Chi Chen, Neng‐Jie Zeng, Grace Y. Liu, Hsien‐Chu Wang, Tzu‐Ying Lin, Yi‐Ling Tai, Chiao‐Yun Chen, Yin Fang, Yi‐Chien Chuang, Ching‐Lin Kao, Hsuan Cheng, Bing‐Huang Wu, Pin‐Chiao Sun, Odvogmed Bayansan, Yu‐Ting Chiu, Chi‐Hsuan Shih, Wen‐Hong Chung, Jia‐Bin Yang, Lily Hui‐Ching Wang, Po‐Han Chiang, Chun‐Hao Chen, Oliver I. Wagner, Yi‐Ching Wang, Yu‐Chun Lin
Publikováno v:
Advanced Science, Vol 11, Iss 45, Pp n/a-n/a (2024)
Abstract Intracellular trafficking, an extremely complex network, dynamically orchestrates nearly all cellular activities. A versatile method that enables the manipulation of target transport pathways with high spatiotemporal accuracy in vitro and in
Externí odkaz:
https://doaj.org/article/f32706deda0442d0979c0a167f5bdc18
Autor:
Yuhan Li, Xianwen Zhang, Wanbo Tai, Xinyu Zhuang, Huicheng Shi, Shumin Liao, Xinyang Yu, Rui Mei, Xingzhao Chen, Yanhong Huang, Yubin Liu, Jianying Liu, Yang Liu, Yibin Zhu, Penghua Wang, Mingyao Tian, Guocan Yu, Liang Li, Gong Cheng
Publikováno v:
EBioMedicine, Vol 110, Iss , Pp 105437- (2024)
Summary: Background: Global dissemination of SARS-CoV-2 Omicron sublineages has provided a sufficient opportunity for natural selection, thus enabling beneficial mutations to emerge. Characterisation of these mutations uncovers the underlying machine
Externí odkaz:
https://doaj.org/article/30828ee07f364a019c79b0ea962e961b
Autor:
Puspangana Singh, Purba Pahari, Srija Mukherjee, Sharmistha Karmakar, Markus Hoffmann, Taraknath Mandal, Dibyendu Kumar Das
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike is the fusion machine for host cell entry. Still, the mechanism by which spike protein interacts with the target lipid membrane to facilitate membrane fusion during entry is
Externí odkaz:
https://doaj.org/article/3f8d6371e091477c8713e7f953d20985
Publikováno v:
Virus Research, Vol 347, Iss , Pp 199433- (2024)
The process of viruses entering host cells is complex, involving multiple aspects of the molecular organization of the cell membrane, viral proteins, the interaction of receptor molecules, and cellular signaling. Most viruses depend on endocytosis fo
Externí odkaz:
https://doaj.org/article/e9ec8868c5c44f3e9d1a218272ce01a9
Autor:
Emma Brown, Gemma Swinscoe, Daniella A Lefteri, Ravi Singh, Amy Moran, Rebecca F Thompson, Daniel Maskell, Hannah Beaumont, Matthew J Bentham, Claire Donald, Alain Kohl, Andrew Macdonald, Neil Ranson, Richard Foster, Clive S McKimmie, Antreas C Kalli, Stephen Griffin
Publikováno v:
eLife, Vol 13 (2024)
Flaviviruses, including Zika virus (ZIKV), are a significant global health concern, yet no licensed antivirals exist to treat disease. The small membrane (M) protein plays well-defined roles during viral egress and remains within virion membranes fol
Externí odkaz:
https://doaj.org/article/2ea2a660429141029618f43cf5ee6d6c
Autor:
Huazhang Zhu, Dawei Wang, Zuodong Ye, Lihong Huang, Wenjie Wei, Kui Ming Chan, Rongxin Zhang, Liang Zhang, Jianbo Yue
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Many viruses enter host cells by hijacking endosomal trafficking. CapZ, a canonical actin capping protein, participates in endosomal trafficking, yet its precise role in endocytosis and virus infection remains elusive. Results Her
Externí odkaz:
https://doaj.org/article/8e664f916c61404889caad51f17ef210
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 539-547 (2023)
Angiotensin-converting enzyme 2 (ACE2) and several proteins have been identified as entry factors for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, whether long noncoding RNAs are involved in SARS-CoV-2 entry remains unknown.
Externí odkaz:
https://doaj.org/article/17862fb8531b40cd94a72b51b04f4f21
Autor:
Martin Jungbauer-Groznica, Konstantin Wiese, Irmgard Fischer, Jan Markus, Tsung-Hsien Chang, Irene Gösler, Heinrich Kowalski, Dieter Blaas, Antonio Real-Hohn
Publikováno v:
Virus Research, Vol 342, Iss , Pp 199338- (2024)
The role of aichivirus A1 (AiV-A1) in acute gastroenteritis remains controversial and in vitro data illustrating its pathogenesis in suitable human models are scarce. Here, we demonstrate that AiV-A1 isolate A846/88 replicates in ApoA1- (absorptive)
Externí odkaz:
https://doaj.org/article/fa7826ffa0a042d996655968b0666c2e
Autor:
Xavier Bonner, Amy Sondgeroth, Amelia McCue, Nathan Nicely, Ashutosh Tripathy, Ean Spielvogel, Matthew Moeser, Ruian Ke, Karin Leiderman, Sarah B. Joseph, Ronald Swanstrom
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTHuman immunodeficiency virus type 1 typically requires a high density of CD4 for efficient entry as a mechanism to target CD4+ T cells (T-tropic), with CCR5 being used most often as the coreceptor. When target T cells are limiting, the virus
Externí odkaz:
https://doaj.org/article/02047abda3bb4f598e57b531a3a08f9d