Zobrazeno 1 - 10
of 102
pro vyhledávání: '"VICTORIA SALEM"'
Autor:
Sine Yaganoglu, Konstantinos Kalyviotis, Christina Vagena-Pantoula, Dörthe Jülich, Benjamin M. Gaub, Maaike Welling, Tatiana Lopes, Dariusz Lachowski, See Swee Tang, Armando Del Rio Hernandez, Victoria Salem, Daniel J. Müller, Scott A. Holley, Julien Vermot, Jian Shi, Nordine Helassa, Katalin Török, Periklis Pantazis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Mechanosensing is a ubiquitous process to translate external mechanical stimuli into biological responses. Piezo1 ion channels are directly gated by mechanical forces and play an essential role in cellular mechanotransduction. However, reado
Externí odkaz:
https://doaj.org/article/adac07eb63d84e5c8bfe4ee63390fede
The vagus nerve mediates the physiological but not pharmacological effects of PYY3-36 on food intake
Autor:
Aldara Martin Alonso, Simon C. Cork, Phyllis Phuah, Benjamin Hansen, Mariana Norton, Sijing Cheng, Xiang Xu, Kinga Suba, Yue Ma, Georgina KC. Dowsett, John A. Tadross, Brian YH. Lam, Giles SH. Yeo, Herbert Herzog, Stephen R. Bloom, Myrtha Arnold, Walter Distaso, Kevin G. Murphy, Victoria Salem
Publikováno v:
Molecular Metabolism, Vol 81, Iss , Pp 101895- (2024)
Peptide YY (PYY3-36) is a post-prandially released gut hormone with potent appetite-reducing activity, the mechanism of action of which is not fully understood. Unravelling how this system physiologically regulates food intake may help unlock its the
Externí odkaz:
https://doaj.org/article/8ca434c5412d4079a5b6bb6f4eff13e9
Autor:
Adam T. Misky, Ronak J. Shah, Chee Yeen Fung, Amir H. Sam, Karim Meeran, Martyn Kingsbury, Victoria Salem
Publikováno v:
BMC Medical Education, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Many prominent UK medical organisations have identified a need for more generalist clinicians to address the complex requirements of an aging society. We sought to clarify attitudes towards “Specialists” and “Generalists”
Externí odkaz:
https://doaj.org/article/a46696f6c79d4f398d6d6d868ce4a4c2
Autor:
Sine Yaganoglu, Konstantinos Kalyviotis, Christina Vagena-Pantoula, Dörthe Jülich, Benjamin M. Gaub, Maaike Welling, Tatiana Lopes, Dariusz Lachowski, See Swee Tang, Armando Del Rio Hernandez, Victoria Salem, Daniel J. Müller, Scott A. Holley, Julien Vermot, Jian Shi, Nordine Helassa, Katalin Török, Periklis Pantazis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/2714c698aa9d44da9cfa19f45f7f95b0
Autor:
Elina Akalestou, Kinga Suba, Livia Lopez-Noriega, Eleni Georgiadou, Pauline Chabosseau, Alasdair Gallie, Asger Wretlind, Cristina Quigley, Isabelle Leclerc, Victoria Salem, Guy A. Rutter
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Bariatric surgery procedures reduce weight and improve metabolic diseases. Here the authors investigate the effects of Vertical Sleeve Gastrectomy (VSG) on beta-cell function in mice using in vivo Ca2 + imaging and show that VSG increases beta-cell f
Externí odkaz:
https://doaj.org/article/8883f2819a32466d8fcddbfc90b52f1e
Publikováno v:
BMJ Open, Vol 12, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/10cff02dd07c464e99412f97b7255d11
Autor:
Daniel S. de Jesus, Tracy C.S. Mak, Yi-Fang Wang, Yorrick von Ohlen, Ying Bai, Eva Kane, Pauline Chabosseau, Catherine M. Chahrour, Walter Distaso, Victoria Salem, Alejandra Tomas, Markus Stoffel, Guy A. Rutter, Mathieu Latreille
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101248- (2021)
Objective: β-cell dedifferentiation has been revealed as a pathological mechanism underlying pancreatic dysfunction in diabetes. We previously showed that increased miR-7 levels trigger β-cell dedifferentiation and diabetes. We used β-cell-specifi
Externí odkaz:
https://doaj.org/article/cfea644ebc5740e49c2574551207d2ef
Autor:
Angela Kim, Jakob G Knudsen, Joseph C Madara, Anna Benrick, Thomas G Hill, Lina Abdul Kadir, Joely A Kellard, Lisa Mellander, Caroline Miranda, Haopeng Lin, Timothy James, Kinga Suba, Aliya F Spigelman, Yanling Wu, Patrick E MacDonald, Ingrid Wernstedt Asterholm, Tore Magnussen, Mikkel Christensen, Tina Vilsbøll, Victoria Salem, Filip K Knop, Patrik Rorsman, Bradford B Lowell, Linford JB Briant
Publikováno v:
eLife, Vol 10 (2021)
Insulin-induced hypoglycemia is a major treatment barrier in type-1 diabetes (T1D). Accordingly, it is important that we understand the mechanisms regulating the circulating levels of glucagon. Varying glucose over the range of concentrations that oc
Externí odkaz:
https://doaj.org/article/706e44ec35864e4a845aaa9f2824dfba
Autor:
Neil E Hill, Nick S Oliver, Wei Yang, Christine Shi, Shivani Misra, Chioma Izzi-Engbeaya, Walter Distaso, Anjali Amin, Oluwagbemiga Idowu, Julia S Kenkre, Ronak J Shah, Evelina Woin, Nael Alavi, Hala Bedri, Niamh Brady, Sophie Blackburn, Martina Leczycka, Sanya Patel, Elizaveta Sokol, Edward Toke-Bjolgerud, Ambreen Qayum, Mariana Abdel-Malek, David C D Hope, Vasiliki Bravis, Tricia M Tan, Victoria Salem
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
Introduction Patients with diabetes mellitus admitted to hospital with COVID-19 have poorer outcomes. However, the drivers of poorer outcomes are not fully elucidated. We performed detailed characterization of patients with COVID-19 to determine the
Externí odkaz:
https://doaj.org/article/7eb1ab04c8e4484f83b7fe832907e545
Autor:
Colby E. Witt, Sergio Mena, Lauren E. Honan, Lauren Batey, Victoria Salem, Yangguang Ou, Parastoo Hashemi
Publikováno v:
Cells, Vol 11, Iss 10, p 1719 (2022)
Serotonin is an important neurotransmitter that plays a major role in many aspects of neuroscience. Fast-scan cyclic voltammetry measures fast in vivo serotonin dynamics using carbon fiber microelectrodes. More recently, fast-scan controlled-adsorpti
Externí odkaz:
https://doaj.org/article/069915c1c8f948ff88871f98cf6c6ba0