Zobrazeno 1 - 10
of 24
pro vyhledávání: '"VI. Genomic variation, diseases and drugs"'
Publikováno v:
Europe PubMed Central
Nucleic Acids Research
Nucleic acids research
Nucleic Acids Research
Nucleic acids research
DNA copy number aberrations (CNAs) can be found in the majority of cancer genomes, and are crucial for understanding the potential mechanisms underlying tumor initiation and progression. Since the first release in 2001, the Progenetix project (http:/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c393995e40c1cfd2c575dbf05ce9f81
http://doc.rero.ch/record/295697/files/gkt1108.pdf
http://doc.rero.ch/record/295697/files/gkt1108.pdf
Autor:
Mathias Dunkel, Robert Preissner, Janette Nickel, Saskia Preissner, Sarah C. Preissner, Michael F. Hoffmann
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research 42 (1): D1113-D1117.
Nucleic Acids Research 42 (1): D1113-D1117.
As the number of prescribed drugs is constantly rising, drug-drug interactions are an important issue. The simultaneous administration of several drugs can cause severe adverse effects based on interactions with the same metabolizing enzyme(s). The T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ba9467705b30a85e39354abbe1fb10
https://doi.org/10.1093/nar/gkt1246
https://doi.org/10.1093/nar/gkt1246
Autor:
Teri A. Manolio, Paul Flicek, Tony Burdett, Alan Klemm, Peggy Hall, Lucia A. Hindorff, Danielle Welter, Joannella Morales, Heather Junkins, Helen Parkinson, Jacqueline A. L. MacArthur
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research; Vol 42
Nucleic Acids Research; Vol 42
The National Human Genome Research Institute (NHGRI) Catalog of Published Genome-Wide Association Studies (GWAS) Catalog provides a publicly available manually curated collection of published GWAS assaying at least 100 000 single-nucleotide polymorph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab62cc39b3efc9513e51d93ff4744e0e
https://doi.org/10.1093/nar/gkt1229
https://doi.org/10.1093/nar/gkt1229
Publikováno v:
Nucleic Acids Research
Antiviral peptides (AVPs) have exhibited huge potential in inhibiting viruses by targeting various stages of their life cycle. Therefore, we have developed AVPdb, available online at http://crdd.osdd.net/servers/avpdb, to provide a dedicated resource
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1329048946b0099f9a48dff93047070a
Publikováno v:
Nucleic Acids Research
In recent years, human regulatory SNPs (rSNPs) have been widely studied. Here, we present database rSNPBase, freely available at http://rsnp.psych.ac.cn/, to provide curated rSNPs that analyses the regulatory features of all SNPs in the human genome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2436df59947815d8d06af51b4331f2f
https://doi.org/10.1093/nar/gkt1167
https://doi.org/10.1093/nar/gkt1167
Publikováno v:
Nucleic Acids Research
Pain is more than an unpleasant sensory experience associated with actual or potential tissue damage: it is the most common reason for physician consultation and often dramatically affects quality of life. The management of pain is often difficult an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b267b36abef1edfe0e329807a761269f
https://doi.org/10.1093/nar/gkt1176
https://doi.org/10.1093/nar/gkt1176
Autor:
Andrew Taylor, Eduardo Berrocal, T. Conrad Gilliam, Sandhya Balasubramanian, Dinanath Sulakhe, Bingqing Xie, Jinbo Xu, Natalia Maltsev, Utpal J. Dave, Daniela Börnigen, Sheng Wang, Bo Feng
Publikováno v:
Nucleic Acids Research
We have developed Lynx (http://lynx.ci.uchicago.edu)—a web-based database and a knowledge extraction engine, supporting annotation and analysis of experimental data and generation of weighted hypotheses on molecular mechanisms contributing to human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5af15753a1de72d691fb50f9d1d885
https://doi.org/10.1093/nar/gkt1166
https://doi.org/10.1093/nar/gkt1166
Autor:
Faiza Hanif Waghu, Susan Idicula-Thomas, Ram Shankar Barai, Lijin Gopi, Bilal Nizami, Pranay Ramteke
Publikováno v:
Nucleic Acids Research
Antimicrobial peptides (AMPs) are gaining importance as anti-infective agents. Here we describe the updated Collection of Antimicrobial Peptide (CAMP) database, available online at http://www.camp.bicnirrh.res.in/. The 3D structures of peptides are k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ab5fb6a7006a2bf23284e5b5f6a9b6
https://doi.org/10.1093/nar/gkt1157
https://doi.org/10.1093/nar/gkt1157
Autor:
Joanna L. Sharman, John A. Peters, Wenyuan Yu, Nc-Iuphar, Anthony P. Davenport, John C. McGrath, Stephen P.H. Alexander, Anthony J. Harmar, Christopher Southan, Michael Spedding, Elena Faccenda, Helen E. Benson, Adam J. Pawson, Peter Buneman
Publikováno v:
Nucleic Acids Research
Pawson, A J, Sharman, J L, Benson, H E, Faccenda, E, Alexander, S P H, Buneman, P O, Davenport, A P, McGrath, J C, Peters, J A, Southan, C, Spedding, M & Yu, W & Harmar, A J 2013, ' The IUPHAR/BPS Guide to PHARMACOLOGY : an expert-driven knowledgebase of drug targets and their ligands ', Nucleic Acids Research . https://doi.org/10.1093/nar/gkt1143
Pawson, A J, Sharman, J L, Benson, H E, Faccenda, E, Alexander, S P H, Buneman, P O, Davenport, A P, McGrath, J C, Peters, J A, Southan, C, Spedding, M & Yu, W & Harmar, A J 2013, ' The IUPHAR/BPS Guide to PHARMACOLOGY : an expert-driven knowledgebase of drug targets and their ligands ', Nucleic Acids Research . https://doi.org/10.1093/nar/gkt1143
The International Union of Basic and Clinical Pharmacology/British Pharmacological Society (IUPHAR/BPS) Guide to PHARMACOLOGY (http://www.guidetopharmacology.org) is a new open access resource providing pharmacological, chemical, genetic, functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8979786227441ddd37f01d37a060b168
https://doi.org/10.1093/nar/gkt1143
https://doi.org/10.1093/nar/gkt1143
Autor:
Guy Georges, Terry Baker, Angelika Fuchs, Charlotte M. Deane, Jiye Shi, Jinwoo Leem, James Dunbar, Konrad Krawczyk
Publikováno v:
Nucleic Acids Research
Structural antibody database (SAbDab; http://opig.stats.ox.ac.uk/webapps/sabdab) is an online resource containing all the publicly available antibody structures annotated and presented in a consistent fashion. The data are annotated with several prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9152c14fc1af3744419fb95a2ea7b542
https://doi.org/10.1093/nar/gkt1043
https://doi.org/10.1093/nar/gkt1043