Synthesis, Physicochemical and Biological Study of Gallium-68- and Lutetium-177-Labeled VEGF-A165/NRP-1 Complex Inhibitors Based on Peptide A7R and Branched Peptidomimetic

Autor: Katarzyna Masłowska, Ewa Witkowska, Dagmara Tymecka, Paweł Krzysztof Halik, Aleksandra Misicka, Ewa Gniazdowska

Publikováno v: Pharmaceutics, Vol 14, Iss 1, p 100 (2022)

Neuropilin-1 (NRP-1) is a surface receptor found on many types of cancer cells. The overexpression of NRP-1 and its interaction with vascular endothelial growth factor-165 (VEGF165) are associated with tumor growth and metastasis. Therefore, compound

Externí odkaz: https://doaj.org/article/677ba72fd4974c24977a5c43d2f12ad6

Synthesis, Physicochemical and Biological Study of Gallium-68- and Lutetium-177-Labeled VEGF-A 165 /NRP-1 Complex Inhibitors Based on Peptide A7R and Branched Peptidomimetic.

Autor: Masłowska K; Centre of Radiochemistry and Nuclear Chemistry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland., Witkowska E; Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland., Tymecka D; Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland., Halik PK; Centre of Radiochemistry and Nuclear Chemistry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland., Misicka A; Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland., Gniazdowska E; Centre of Radiochemistry and Nuclear Chemistry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland.

Publikováno v: Pharmaceutics [Pharmaceutics] 2022 Jan 01; Vol. 14 (1). Date of Electronic Publication: 2022 Jan 01.