DYRK1a Inhibitor Mediated Rescue of Drosophila Models of Alzheimer’s Disease-Down Syndrome Phenotypes

Autor: Zhu, Bangfu, Parsons, Tom A, Stensen, Wenche, Mjøen Svendsen, John S, Fugelli, Anders, Hodge, James J L

Publikováno v: Zhu, B, Parsons, T A, Stensen, W, Mjøen Svendsen, J S, Fugelli, A & Hodge, J J L 2022, ' DYRK1a inhibitor mediated rescue of Drosophila models of Alzheimer’s disease-Down Syndrome phenotypes ', Frontiers in Pharmacology, vol. 13, 881385 . https://doi.org/10.3389/fphar.2022.881385

Alzheimer’s disease (AD) is the most common neurodegenerative disease which is becoming increasingly prevalent due to ageing populations resulting in huge social, economic, and health costs to the community. Despite the pathological processing of g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2fe4e1bd0be601c5d280db3add76d49
https://hdl.handle.net/10037/26607

Six versus 2 weeks treatment with doxycycline in European Lyme neuroborreliosis: a multicentre, noninferiority, double-blinded, randomised and placebocontrolled trial

Autor: Anne Marit Solheim, Åslaug Rudjord Lorentzen, Audun Olav Dahlberg, Heidi Øyen Flemmen, Synne Brune, Kristine Johanne Nordstrøm Forselv, Are Hugo Pripp, Margrete Halvorsen Bø, Randi Eikeland, Harald Reiso, Åse Mygland, Unn Ljøstad

Publikováno v: Journal of Neurology, Neurosurgery and Psychiatry

BackgroundThere is limited evidence regarding optimal duration of antibiotic treatment in neuroborreliosis. We aimed to compare efficacy and safety of oral doxycycline for 2 and 6 weeks in European Lyme neuroborreliosis (LNB).MethodsThe trial had a r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e88f68ced156a2ec112205392d98af
https://hdl.handle.net/11250/3017836

Aspects on Recanalisation Therapies for Acute Ischaemic Stroke. Long-term survival after thrombolytic treatment with alteplase, endovascular thrombectomy for acute ischaemic stroke and recanalisation therapies for wake-up stroke

Autor: Roaldsen, Melinda Berg

Stroke is a leading cause of death and disability worldwide. Approximately 85% of strokes are ischaemic strokes caused by blockage of a brain artery. Recanalisation therapies with thrombolysis (injection of drugs that dissolve the blood clot) and thr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::93bcda3da014147ce2e5b286294d775e
https://hdl.handle.net/10037/23590

Enhancement of cranial nerves in Lyme neuroborreliosis: incidence and correlation with clinical symptoms and prognosis

Autor: Elisabeth S. Lindland, Anne Marit Solheim, Muhammad Nazeer Dareez, Randi Eikeland, Unn Ljøstad, Åse Mygland, Harald Reiso, Åslaug R. Lorentzen, Hanne F. Harbo, Mona K. Beyer

Publikováno v: 2323–2333
Neuroradiology

Purpose Symptoms of cranial neuritis are a common presentation of Lyme neuroborreliosis (LNB). Imaging studies are scarce and report contradictory low prevalence of enhancement compared to clinical studies of cranial neuropathy. We hypothesized that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ea6b1d5098d7cdff3247f481649ca6
https://hdl.handle.net/11250/3042565

The Effect of Smoking on Long-term Gray Matter Atrophy and Clinical Disability in Patients with Relapsing-Remitting Multiple Sclerosis

Autor: Ingrid Anne Lie, Kristin Wesnes, Silje S. Kvistad, Iman Brouwer, Stig Wergeland, Trygve Holmøy, Rune Midgard, Alla Bru, Astrid Edland, Randi Eikeland, Sonia Gosal, Hanne F. Harbo, Grethe Kleveland, Yvonne S. Sørenes, Nina Øksendal, Frederik Barkhof, Hugo Vrenken, Kjell-Morten Myhr, Lars Bø, Øivind Torkildsen

Publikováno v: e200008
Neurology, Neuroimmunology and Neuroinflammation
Neurology: Neuroimmunology and neuroinflammation
Lie, I A, Wesnes, K, Kvistad, S S, Brouwer, I, Wergeland, S, Holmøy, T, Midgard, R, Bru, A, Edland, A, Eikeland, R, Gosal, S, Harbo, H F, Kleveland, G, Sørenes, Y S, Øksendal, N, Barkhof, F, Vrenken, H, Myhr, K-M, Bø, L & Torkildsen, Ø 2022, ' The Effect of Smoking on Long-term Gray Matter Atrophy and Clinical Disability in Patients with Relapsing-Remitting Multiple Sclerosis ', Neurology(R) neuroimmunology & neuroinflammation, vol. 9, no. 5 . https://doi.org/10.1212/NXI.0000000000200008
Neurology(R) neuroimmunology & neuroinflammation, 9(5). Lippincott Williams and Wilkins

Background and ObjectivesThe relationship between smoking, long-term brain atrophy, and clinical disability in patients with multiple sclerosis (MS) is unclear. Here, we assessed long-term effects of smoking by evaluating MRI and clinical outcome mea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d41627f04e3c1648d98ff97e2549d1
http://hdl.handle.net/10852/98913