Zobrazeno 1 - 5
of 5
pro vyhledávání: '"VDP::Mathematics and natural scienses: 400::Chemistry: 440::Pharmaceutical chemistry: 448"'
Autor:
Hymonti Dey, Danijela Simonovic, Ingrid Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke, Trude Anderssen, Morten B. Strøm, Tor Haug
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 13844
We have synthesised short analogues of the marine antimicrobial peptide Turgencin A from the colonial Arctic ascidian Synoicum turgens. In this study, we focused on a central, cationic 12-residue Cys-Cys loop region within the sequence. Modified (try
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e0f86fb7635e0ad6aaccbb6c576b18
https://pubmed.ncbi.nlm.nih.gov/36430320
https://pubmed.ncbi.nlm.nih.gov/36430320
Autor:
Zhu, Bangfu, Parsons, Tom A, Stensen, Wenche, Mjøen Svendsen, John S, Fugelli, Anders, Hodge, James J L
Publikováno v:
Zhu, B, Parsons, T A, Stensen, W, Mjøen Svendsen, J S, Fugelli, A & Hodge, J J L 2022, ' DYRK1a inhibitor mediated rescue of Drosophila models of Alzheimer’s disease-Down Syndrome phenotypes ', Frontiers in Pharmacology, vol. 13, 881385 . https://doi.org/10.3389/fphar.2022.881385
Alzheimer’s disease (AD) is the most common neurodegenerative disease which is becoming increasingly prevalent due to ageing populations resulting in huge social, economic, and health costs to the community. Despite the pathological processing of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2fe4e1bd0be601c5d280db3add76d49
https://hdl.handle.net/10037/26607
https://hdl.handle.net/10037/26607
Autor:
Manuel K. Langer, Ataur Rahman, Hymonti Dey, Trude Anderssen, Francesco Zilioli, Tor Haug, Hans-Matti Blencke, Klara Stensvåg, Morten B. Strøm, Annette Bayer
Publikováno v:
European Journal of Medicinal Chemistry. 241:114632
An amphipathic barbiturate mimic of the marine eusynstyelamides is reported as a promising class of antimicrobial agents. We hereby report a detailed analysis of the structure-activity relationship for cationic amphipathic N,N′ -dialkylated-5,5-dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9160fcfce483db116bf350bd267febfa
https://doi.org/10.1016/j.ejmech.2022.114632
https://doi.org/10.1016/j.ejmech.2022.114632
Autor:
Dominik Ausbacher, Johanna U. Ericson Sollid, Terkel Hansen, Marianne Hagensen Paulsen, Annette Bayer, Tor Haug, Magnus Engqvist, Morten B. Strøm, Trude Anderssen, Jeanette Hammer Andersen
Source at https://doi.org/10.1016/j.ejmech.2019.111671. The rapid emergence and spread of multi-resistant bacteria have created an urgent need for new antimicrobial agents. We report here a series of amphipathic α,α-disubstituted β-amino amide der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e52239e41a7ff50a8b7b5706d8fdef1
https://hdl.handle.net/10037/16259
https://hdl.handle.net/10037/16259
Publikováno v:
Future Medicinal Chemistry. 7:1261-1283
Accepted manuscript version. Published version available at http://dx.doi.org/10.4155/fmc.15.64 Over the last five years, X-ray structures of CXC chemokine receptor 4 (CXCR4) in complex with three different ligands (the small-molecule antagonist IT1t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6f7a7e75531ff2cd17b662f6f6db908
https://doi.org/10.4155/fmc.15.64
https://doi.org/10.4155/fmc.15.64