Zobrazeno 1 - 10
of 33
pro vyhledávání: '"VCAM = vascular cell adhesion molecule"'
Autor:
Michael Baboudjian, Bastien Gondran-Tellier, Romain Boissier, Patricia Ancel, Juline Marjollet, Luc Lyonnet, Pauline François, Florence Sabatier, Eric Lechevallier, Anne Dutour, Pascale Paul
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundWe aimed to evaluate whether donor-related inflammatory markers found in kidney transplant preservation fluid can associate with early development of kidney allograft dysfunction.MethodsOur prospective study enrolled 74 consecutive donated
Externí odkaz:
https://doaj.org/article/1f4bd09580e0403eb5e5fc0903c60afc
Autor:
Caifang Gao, Peng Liu, Hongguo Chen, Xu Wu, Xudong Tang, Yitao Wang, Chi Teng Vong, Shengpeng Wang
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2798-2818 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2798-2818 (2021)
Inflammatory bowel disease (IBD) is a chronic intestinal disease with painful clinical manifestations and high risks of cancerization. With no curative therapy for IBD at present, the development of effective therapeutics is highly advocated. Drug de
Akademický článek
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Autor:
Barry Halliwell, Irwin K. Cheah
Publikováno v:
Redox Biology, Vol 42, Iss, Pp 101868-(2021)
Redox Biology
Redox Biology
There has been a recent surge of interest in the unique low molecular weight dietary thiol/thione, ergothioneine. This compound can accumulate at high levels in the body from diet and may play important physiological roles in human health and develop
Publikováno v:
Advanced Drug Delivery Reviews
Advanced Drug Delivery Reviews, Elsevier, 2020, 157, pp.161-178. ⟨10.1016/j.addr.2020.07.010⟩
Advanced Drug Delivery Reviews, Elsevier, 2020, 157, pp.161-178. ⟨10.1016/j.addr.2020.07.010⟩
Inflammation, a common feature of many diseases, is an essential immune response that enables survival and maintains tissue homeostasis. However, in some conditions, the inflammatory process becomes detrimental, contributing to the pathogenesis of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c0b83d8ad1c4e5e69f43542fb2ec71
https://hal.archives-ouvertes.fr/hal-03493936
https://hal.archives-ouvertes.fr/hal-03493936
Publikováno v:
Journal of Advanced Research
Graphical abstract
Introduction Recently, Nrf2/HO-1 has received extensive attention as the main regulatory pathway of intracellular defense against oxidative stress and is considered an ideal target for alleviating endothelial cell (EC) injury.
Introduction Recently, Nrf2/HO-1 has received extensive attention as the main regulatory pathway of intracellular defense against oxidative stress and is considered an ideal target for alleviating endothelial cell (EC) injury.
Autor:
Kikkie Poels, Venkatesh Mani, Myrthe E. Reiche, Mandy M. T. van Leent, Stephan Huveneers, Audrey E Kaufman, Hubert Tissot, Yohana C. Toner, Esther Lutgens, Menno P.J. de Winther, Celine Boutros, Zahi A. Fayad, Tsveta S. Malinova, Pascal J. H. Kusters, Aurélien Marabelle, Séverine Roy, Tom Seijkens, Caroline Robert, Willem J. M. Mulder, Anu E. Meerwaldt
Publikováno v:
JACC: CardioOncology
JACC: CardioOncology, 2(4), 599-610. Elsevier
JACC: CardioOncology, 2(4), 599-610. Elsevier Inc.
JACC: CardioOncology, 2(4), 599-610. Elsevier
JACC: CardioOncology, 2(4), 599-610. Elsevier Inc.
Background Immunotherapy has revolutionized cancer treatment. However, immune checkpoint inhibitors (ICIs) that target PD-1 (programmed cell death protein-1) and/or CTLA-4 (cytotoxic T lymphocyte-associated antigen-4) are commonly associated with acu
Autor:
Kwong Man Ng, Jamie Morton, Joanne T.M. Tan, Laura Z. Vanags, Anisyah Ridiandries, David S. Celermajer, Tania Tsatralis, Shisan Bao, Chung-Wah Siu, Martin K.C. Ng, Christina A. Bursill
Publikováno v:
JACC: Basic to Translational Science, Vol 3, Iss 2, Pp 187-199 (2018)
JACC: Basic to Translational Science
JACC: Basic to Translational Science
Visual Abstract
Highlights • The atheroprotective effects of apoA-I are dependent on the plaque stage from which apoA-I is infused. • The atheroprotective effects of apoA-I infusions are also impaired in older mice with a greater disease mil
Highlights • The atheroprotective effects of apoA-I are dependent on the plaque stage from which apoA-I is infused. • The atheroprotective effects of apoA-I infusions are also impaired in older mice with a greater disease mil
Autor:
Shyam S. Bansal, Bindiya Patel, Sumanth D. Prabhu, Tariq Hamid, Matthias Mack, Gregg Rokosh, Mohamed Ameen Ismahil
Publikováno v:
JACC: Basic to Translational Science, Vol 3, Iss 2, Pp 230-244 (2018)
JACC: Basic to Translational Science
JACC: Basic to Translational Science
Visual Abstract
Highlights • Hypothesis: CCR2+ monocyte-derived cardiac macrophages are required for adverse LV remodeling, cardiac T-cell expansion, and the transition to HF following pressure overload. • The imposition of pressure overload
Highlights • Hypothesis: CCR2+ monocyte-derived cardiac macrophages are required for adverse LV remodeling, cardiac T-cell expansion, and the transition to HF following pressure overload. • The imposition of pressure overload
Autor:
Mia, Ståhle, Johanna M U, Silvola, Sanna, Hellberg, Margreet, de Vries, Paul H A, Quax, Jeffrey, Kroon, Petteri, Rinne, Alwin, de Jong, Heidi, Liljenbäck, Nina, Savisto, Anna, Wickman, Erik S G, Stroes, Seppo, Ylä-Herttuala, Pekka, Saukko, Tommy, Abrahamsson, Knut, Pettersson, Juhani, Knuuti, Anne, Roivainen, Antti, Saraste
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • Phosphorylcholine is a pro-inflammatory epitope in atherogenic oxidized phospholipids. • This study investigated effects of a novel monoclonal IgG1 antibody against PC on vascular function and atherosclerotic inf
Highlights • Phosphorylcholine is a pro-inflammatory epitope in atherogenic oxidized phospholipids. • This study investigated effects of a novel monoclonal IgG1 antibody against PC on vascular function and atherosclerotic inf