Zobrazeno 1 - 10
of 2 855
pro vyhledávání: '"VAUGHAN G."'
Autor:
Vaughan G. Macefield, Lyndon J. Smith, Lucy Norcliffe‐Kaufmann, Jose‐Alberto Palma, Horacio Kaufmann
Publikováno v:
Experimental Physiology, Vol 109, Iss 1, Pp 27-34 (2024)
Abstract Hereditary sensory and autonomic neuropathy type III (HSAN III), also known as familial dysautonomia or Riley–Day syndrome, results from an autosomal recessive genetic mutation that causes a selective loss of specific sensory neurones, lea
Externí odkaz:
https://doaj.org/article/3375a4a16cd24be5a407d03b8f674a64
Autor:
Lewis S. Crawford, Noemi Meylakh, Paul M. Macey, Vaughan G. Macefield, Kevin A. Keay, Luke A. Henderson
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract The neural circuits that regulate placebo analgesia responsivity are unknown, although engagement of brainstem pain modulatory regions is likely critical. Here we show in 47 participants that differences are present in neural circuit connect
Externí odkaz:
https://doaj.org/article/db2dd864c8a144beaac1bb757b618a6a
Autor:
Radhagayathri Udhayakumar, Saifur Rahman, Dilpreet Buxi, Vaughan G. Macefield, Tye Dawood, Nicholas Mellor, Chandan Karmakar
Publikováno v:
Royal Society Open Science, Vol 10, Iss 8 (2023)
The onset of stress triggers sympathetic arousal (SA), which causes detectable changes to physiological parameters such as heart rate, blood pressure, dilation of the pupils and sweat release. The objective quantification of SA has tremendous potenti
Externí odkaz:
https://doaj.org/article/0f42439767ea4bfcabca3045c7ba0e58
Autor:
Tiffani J. Mungoven, Kasia K. Marciszewski, Vaughan G. Macefield, Paul M. Macey, Luke A. Henderson, Noemi Meylakh
Publikováno v:
The Journal of Headache and Pain, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract Background The precise underlying mechanisms of migraine remain unknown. Although we have previously shown acute orofacial pain evoked changes within the brainstem of individuals with migraine, we do not know if these brainstem alterations a
Externí odkaz:
https://doaj.org/article/623e4d8b13da47e1bcc273c918489154
Autor:
Jens Spiesshoefer, Alberto Giannoni, Chiara Borrelli, Paolo Sciarrone, Imke Husstedt, Michele Emdin, Claudio Passino, Florian Kahles, Tye Dawood, Binaya Regmi, Matthew Naughton, Michael Dreher, Matthias Boentert, Vaughan G. Macefield
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Background: Periodic breathing (PB) is a cyclical breathing pattern composed of alternating periods of hyperventilation (hyperpnea, HP) and central apnea (CA). Differences in PB phenotypes mainly reside in HP length. Given that respiration modulates
Externí odkaz:
https://doaj.org/article/66f384cc5f554867bca9346211933dfe
Publikováno v:
Frontiers in Pain Research, Vol 3 (2022)
The pathophysiology of migraine remains to be elucidated. We have recently shown that interictal migraineurs exhibit reduced fractional anisotropy (FA) in the root entry zone of the trigeminal nerve when compared to controls, but it is not known if t
Externí odkaz:
https://doaj.org/article/5fbf5dc0f7424538a0c18dfe2a415961
Autor:
Tiffani J. Mungoven, Noemi Meylakh, Kasia K. Marciszewski, Vaughan G. Macefield, Paul M. Macey, Luke A. Henderson
Publikováno v:
The Journal of Headache and Pain, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background There is histological evidence of microstructural changes in the zygomaticotemporal branch of the trigeminal nerve in migraineurs. This raises the possibility that altered trigeminal nerve properties contribute to migraine pathoph
Externí odkaz:
https://doaj.org/article/49614d9ea05041989b8612b17dc8fe06
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
We previously demonstrated that muscle sympathetic nerve activity (MSNA) increases to contracting muscle as well as to non-contracting muscle, but this was only assessed during isometric exercise at ∼10% of maximum voluntary contraction (MVC). Give
Externí odkaz:
https://doaj.org/article/e6fcfbc46758435faa9e5a88cbb7ef80
Autor:
Kim L. Powell, Zining Liu, Claire L. Curl, Antonia J.A. Raaijmakers, Pragati Sharma, Emma L. Braine, Flavia M. Gomes, Shobi Sivathamboo, Vaughan G. Macefield, Pablo M. Casillas-Espinosa, Nigel C. Jones, Lea M. Delbridge, Terence J. O’Brien
Publikováno v:
Neurobiology of Disease, Vol 159, Iss , Pp 105505- (2021)
Objective: This study aimed to prospectively examine cardiac structure and function in the kainic acid-induced post-status epilepticus (post-KA SE) model of chronic acquired temporal lobe epilepsy (TLE), specifically to examine for changes between th
Externí odkaz:
https://doaj.org/article/2f278a222be74d4a903bacd65e7a477e
Autor:
Gregory D. Rankin, Mikael Kabéle, Rachael Brown, Vaughan G. Macefield, Thomas Sandström, Jenny A. Bosson
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 10 (2021)
Background Diesel exhaust (DE) emissions are a major contributor to ambient air pollution and are strongly associated with cardiovascular morbidity and mortality. Exposure to traffic‐related particulate matter is linked with acute adverse cardiovas
Externí odkaz:
https://doaj.org/article/37f7f598bed1479b9be84f90f61702e6