Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor

Autor: Ganichkin, O.M., Vancraenenbroeck, R., Rosenblum, G., Hofmann, H., Mikhailov, A.S., Daumke, O., Noel, J.K.

Dynamin oligomerizes into helical filaments on tubular membrane templates and, through constriction, cleaves them in a GTPase-driven way. Structural observations of GTP-dependent cross-bridges between neighboring filament turns have led to the sugges

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=mdc______med::aa3644dd41a91b445bfc8aad2daeeec6
http://edoc.mdc-berlin.de/20422/1/20422.pdf

Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor.

Autor: Ganichkin OM; Crystallography, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany., Vancraenenbroeck R; Department of Chemical and Structural Biology, Weizmann Institute of Science, 76100 Rehovot, Israel., Rosenblum G; Department of Chemical and Structural Biology, Weizmann Institute of Science, 76100 Rehovot, Israel., Hofmann H; Department of Chemical and Structural Biology, Weizmann Institute of Science, 76100 Rehovot, Israel., Mikhailov AS; Department of Physical Chemistry, Fritz Haber Institute of the Max Planck Society, 14195 Berlin, Germany.; Computational Molecular Biophysics, Nano Life Science Institute, Kanazawa University, Kanazawa 920-1192, Japan., Daumke O; Crystallography, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany; jeffrey.noel@mdc-berlin.de oliver.daumke@mdc-berlin.de.; Institute for Chemistry and Biochemistry, Free University of Berlin, 14195 Berlin, Germany., Noel JK; Crystallography, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany; jeffrey.noel@mdc-berlin.de oliver.daumke@mdc-berlin.de.; Department of Physical Chemistry, Fritz Haber Institute of the Max Planck Society, 14195 Berlin, Germany.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jul 13; Vol. 118 (28).

Polymer effects modulate binding affinities in disordered proteins.

Autor: Vancraenenbroeck R; Department of Structural Biology, Weizmann Institute of Science, 76100 Rehovot, Israel., Harel YS; Department of Structural Biology, Weizmann Institute of Science, 76100 Rehovot, Israel., Zheng W; College of Integrative Sciences and Arts, Arizona State University, Mesa, AZ 85212., Hofmann H; Department of Structural Biology, Weizmann Institute of Science, 76100 Rehovot, Israel; hagen.hofmann@weizmann.ac.il.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Sep 24; Vol. 116 (39), pp. 19506-19512. Date of Electronic Publication: 2019 Sep 05.

An Overview of Epigenetic Changes in the Parkinson's Disease Brain.

Autor: Klokkaris, Anthony¹ (AUTHOR) ak735@exeter.ac.uk, Migdalska-Richards, Anna¹ (AUTHOR) a.migdalska-richards@exeter.ac.uk

Publikováno v: International Journal of Molecular Sciences. Jun2024, Vol. 25 Issue 11, p6168. 32p.

Cryo-EM analysis of homodimeric full-length LRRK2 and LRRK1 protein complexes.

Autor: Sejwal K; Center for Cellular Imaging and NanoAnalytics (C-CINA), Biozentrum, University of Basel, Basel, 4056, Switzerland., Chami M; Center for Cellular Imaging and NanoAnalytics (C-CINA), Biozentrum, University of Basel, Basel, 4056, Switzerland., Rémigy H; FEI Company, Eindhoven, The Netherlands., Vancraenenbroeck R; KU Leuven, Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, 3000, Leuven, Belgium.; Department of Structural Biology, Weizmann Institute of Science, Rehovot, 76100, Israel., Sibran W; Université de Lille, Inserm, CHU Lille, UMR-S1172 - JPArc - Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer, F-59000, Lille, France., Sütterlin R; Center for Cellular Imaging and NanoAnalytics (C-CINA), Biozentrum, University of Basel, Basel, 4056, Switzerland., Baumgartner P; Center for Cellular Imaging and NanoAnalytics (C-CINA), Biozentrum, University of Basel, Basel, 4056, Switzerland., McLeod R; Center for Cellular Imaging and NanoAnalytics (C-CINA), Biozentrum, University of Basel, Basel, 4056, Switzerland., Chartier-Harlin MC; Université de Lille, Inserm, CHU Lille, UMR-S1172 - JPArc - Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer, F-59000, Lille, France., Baekelandt V; KU Leuven, Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, 3000, Leuven, Belgium., Stahlberg H; Center for Cellular Imaging and NanoAnalytics (C-CINA), Biozentrum, University of Basel, Basel, 4056, Switzerland. henning.stahlberg@unibas.ch., Taymans JM; KU Leuven, Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, 3000, Leuven, Belgium. jean-marc.taymans@inserm.fr.; Université de Lille, Inserm, CHU Lille, UMR-S1172 - JPArc - Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer, F-59000, Lille, France. jean-marc.taymans@inserm.fr.

Publikováno v: Scientific reports [Sci Rep] 2017 Aug 17; Vol. 7 (1), pp. 8667. Date of Electronic Publication: 2017 Aug 17.