Resveratrol attenuates NF-κB-binding activity but not cytokine production in mechanically ventilated mice

Autor: Van Der Wal, S. E.I., Vaneker, M., Kox, M., Braak, G., Van Hees, H. W.H., Van Den Brink, I. A., Van De Pol, F. M., Heunks, L. M., Van Der Hoeven, J. G., Joosten, L. A.B., Vissers, K. C.P., Scheffer, G. J.

Publikováno v: Acta Anaesthesiologica Scandinavica, 58(4), 487-494. Blackwell Munksgaard
Van Der Wal, S E I, Vaneker, M, Kox, M, Braak, G, Van Hees, H W H, Van Den Brink, I A, Van De Pol, F M, Heunks, L M, Van Der Hoeven, J G, Joosten, L A B, Vissers, K C P & Scheffer, G J 2014, ' Resveratrol attenuates NF-κB-binding activity but not cytokine production in mechanically ventilated mice ', Acta Anaesthesiologica Scandinavica, vol. 58, no. 4, pp. 487-494 . https://doi.org/10.1111/aas.12276

Background Mechanical ventilation (MV) can result in inflammation and subsequent lung injury. Toll-like receptor (TLR)4 and NF-κB are proposed to play a crucial role in the MV-induced inflammatory response. Resveratrol (RVT) exhibits anti-inflammato

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