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FcRn mediated IgG transport by retinal pigment epithelium cells

Autor: Korthagen Nicoline M, van Bilsen Kiki, Dik Willem A, Bastiaans Jeroen, Kolijn Marion, Kuijpers Robert W, van Hagen Martin

Publikováno v: Journal of Translational Medicine, Vol 10, Iss Suppl 3, p P2 (2012)

Externí odkaz: https://doaj.org/article/afbf4a95a6844a0781c2e811105f9106

Chloroquine and Hydroxychloroquine Increase Retinal Pigment Epithelial Layer Permeability

Autor: Korthagen, Nicoline, Bastiaans, Jeroen, van Meurs, Johan, van Bilsen, Kiki, van Hagen, P.M., Dik, Wim

Publikováno v: Journal of Biochemical and Molecular Toxicology, 29(7), 299-304. John Wiley & Sons Inc.

Antimalarials chloroquine (CQ) and hydroxychloroquine (HCQ) are widely used as antiinflammatory drugs, but side effects include retinopathy and vision loss. The objective of this study was to examine the effect of CQ and HCQ on the barrier integrity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::4b797bc39a67ed616d8c62e5be957e7c
https://pure.eur.nl/en/publications/a6a0ba5a-44d0-4bb4-95bb-d2c5c784713d

Retinal pigment epithelial cells display specific transcriptional responses upon TNF-α stimulation

Autor: Korthagen, Nicoline M, van Bilsen, Kiki, Swagemakers, Sigrid M A, van de Peppel, Jeroen, Bastiaans, Jeroen, van der Spek, Peter J, van Hagen, P Martin, Dik, Willem A, Regenerative Medicine, Stem Cells & Cancer, dES RMSC

Publikováno v: British Journal of Ophthalmology, 99, 700. BMJ Publishing Group
British Journal of Ophthalmology, 99(5), 700-704. BMJ Publishing Group

Background/aims Tumour necrosis factor-alpha (TNF-alpha) is a key mediator of ocular inflammation and its interaction with the retinal pigment epithelium (RPE) may be a driving force in vitreoretinal disorders such as age-related macular degeneration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac996b56aecb1235ea85d53d83bce22
https://doi.org/10.1136/bjophthalmol-2014-306309

Chloroquine and Hydroxychloroquine Increase Retinal Pigment Epithelial Layer Permeability.

Autor: Korthagen NM; Department of Immunology, Erasmus MC, University Medical Center, P.O. Box 2060, 3000, CB, Rotterdam, The Netherlands., Bastiaans J; Department of Immunology, Erasmus MC, University Medical Center, P.O. Box 2060, 3000, CB, Rotterdam, The Netherlands., van Meurs JC; The Rotterdam Eye Hospital, P.O. Box 70030, 3000, LM, Rotterdam, The Netherlands.; Department of Ophthalmology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands., van Bilsen K; Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands., van Hagen PM; Department of Immunology, Erasmus MC, University Medical Center, P.O. Box 2060, 3000, CB, Rotterdam, The Netherlands.; The Rotterdam Eye Hospital, P.O. Box 70030, 3000, LM, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands., Dik WA; Department of Immunology, Erasmus MC, University Medical Center, P.O. Box 2060, 3000, CB, Rotterdam, The Netherlands.

Publikováno v: Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2015 Jul; Vol. 29 (7), pp. 299-304. Date of Electronic Publication: 2015 Mar 09.